AutismKB 2.0

Annotation Detail for ZNF434


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Basic Information Top
Gene Symbol:ZNF434 ( FLJ20417,FLJ31901,MGC4179 )
Gene Full Name: zinc finger protein 434
Band: 16p13.3
Quick LinksEntrez ID:54925; OMIM: NA; Uniprot ID:ZN434_HUMAN; ENSEMBL ID: ENSG00000140987; HGNC ID:
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst2 / 6231932
fetus21 / 56401237
neonate0 / 310970 
infant0 / 236200 
juvenile2 / 5555635
adult42 / 193912121
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor6 / 9417863
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor2 / 11424617
esophageal tumor0 / 172900 
gastrointestinal tumor5 / 11936941
germ cell tumor6 / 26384522
glioma6 / 10688356
head and neck tumor2 / 13630214
kidney tumor5 / 6895972
leukemia3 / 9584231
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia6 / 9725061
normal73 / 336030721
ovarian tumor1 / 7668213
pancreatic tumor3 / 10461628
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer2 / 10268019
retinoblastoma1 / 4635621
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites1 / 4001524
bladder0 / 297570 
blood4 / 12347832
bone0 / 716550 
bone marrow0 / 488010 
brain24 / 110098921
cervix0 / 481710 
connective tissue5 / 14925533
ear0 / 162120 
embryonic tissue10 / 21572246
esophagus0 / 202090 
eye4 / 21105418
heart2 / 8962622
intestine3 / 23447212
kidney7 / 21177733
larynx0 / 241450 
liver2 / 2077439
lung10 / 33697429
lymph0 / 442700 
lymph node1 / 9161010
mammary gland6 / 15327139
mouth2 / 6705229
muscle2 / 10771518
nerve0 / 157680 
ovary1 / 1020519
pancreas7 / 21481232
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta2 / 2808257
prostate3 / 18934515
salivary gland0 / 201550 
skin4 / 21057418
spleen0 / 539520 
stomach4 / 9661941
testis14 / 33044242
thymus2 / 8113124
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus4 / 23287817
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 218937_at
Cell line Expression level Expression bar
721_B_lymphoblasts6.1
Adipocyte4.2
AdrenalCortex4.45
Adrenalgland4.75
Amygdala4.45
Appendix4.55
AtrioventricularNode3.3
BDCA4+_DentriticCells5.1
Bonemarrow4.3
BronchialEpithelialCells4.2
CD105+_Endothelial4.35
CD14+_Monocytes4.6
CD19+_BCells(neg._sel.)6.05
CD33+_Myeloid5.35
CD34+6.7
CD4+_Tcells5.75
CD56+_NKCells6.3
CD71+_EarlyErythroid4.5
CD8+_Tcells4.25
CardiacMyocytes5.4
Caudatenucleus3.8
Cerebellum4.1
CerebellumPeduncles4.95
CiliaryGanglion3.05
CingulateCortex4.45
Colorectaladenocarcinoma4.3
DorsalRootGanglion3.25
FetalThyroid4.25
Fetalbrain4.65
Fetalliver3.7
Fetallung3.4
GlobusPallidus3.15
Heart5.4
Hypothalamus4.8
Kidney3.5
Leukemia_chronicMyelogenousK-5623.9
Leukemia_promyelocytic-HL-603.8
Leukemialymphoblastic(MOLT-4)4
Liver5.9
Lung4.65
Lymphnode3.7
Lymphoma_burkitts(Daudi)5.55
Lymphoma_burkitts(Raji)5.85
MedullaOblongata3.85
OccipitalLobe3.95
OlfactoryBulb3.35
Ovary2.85
Pancreas3.4
PancreaticIslet4.6
ParietalLobe4.5
Pituitary5.25
Placenta4.4
Pons4
PrefrontalCortex5.3
Prostate5.05
Salivarygland3.6
SkeletalMuscle5.15
Skin3.3
SmoothMuscle4.95
Spinalcord4.55
SubthalamicNucleus3.9
SuperiorCervicalGanglion4.8
TemporalLobe3.85
Testis4.8
TestisGermCell3.5
TestisIntersitial4
TestisLeydigCell4.15
TestisSeminiferousTubule3.65
Thalamus4.35
Thymus3.4
Thyroid5.35
Tongue4.2
Tonsil4.15
Trachea3.6
TrigeminalGanglion4.2
Uterus3.6
UterusCorpus4.4
WholeBlood4.8
Wholebrain3.7
colon4.3
pineal_day5.24
pineal_night5.28
retina5.175
small_intestine4.1
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P218282
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.78 ± 0.56
Basal Forebrain3.85 ± 0.51
Basal Part of Pons3.9 ± 0.58
Cerebellar Cortex3.93 ± 0.57
Cerebellar Nuclei3.84 ± 0.54
Claustrum3.57 ± 0.58
Epithalamus3.94 ± 0.72
Frontal Lobe3.84 ± 0.56
Globus Pallidus4.34 ± 0.36
Hypothalamus3.61 ± 0.4
Insula3.71 ± 0.56
Limbic Lobe3.61 ± 0.48
Mesencephalon3.98 ± 0.59
Myelencephalon3.81 ± 0.55
Occipital Lobe3.86 ± 0.49
Parietal Lobe3.76 ± 0.56
Pontine Tegmentum3.85 ± 0.53
Striatum3.95 ± 0.53
Subthalamus3.56 ± 0.77
Temporal Lobe3.77 ± 0.56
Thalamus4 ± 0.52
White Matter4.97 ± 0.39
Mouse Brain ISH
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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