AutismKB 2.0

Annotation Detail for EXD3


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Basic Information Top
Gene Symbol:EXD3 ( FLJ20433,FLJ30442,MGC131904,MGC74981,mut-7 )
Gene Full Name: exonuclease 3'-5' domain containing 3
Band: 9q34.3
Quick LinksEntrez ID:54932; OMIM: NA; Uniprot ID:MUT7_HUMAN; ENSEMBL ID: ENSG00000187609; HGNC ID: 26023
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst2 / 6231932
fetus12 / 56401221
neonate0 / 310970 
infant1 / 2362042
juvenile0 / 555560 
adult22 / 193912111
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma4 / 8282348
colorectal tumor2 / 11424617
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor3 / 26384511
glioma2 / 10688318
head and neck tumor0 / 1363020 
kidney tumor1 / 6895914
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor4 / 10312738
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal54 / 336030716
ovarian tumor0 / 766820 
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS7 / 12568055
prostate cancer2 / 10268019
retinoblastoma0 / 463560 
skin tumor1 / 1249498
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone4 / 7165555
bone marrow0 / 488010 
brain26 / 110098923
cervix0 / 481710 
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue3 / 21572213
esophagus0 / 202090 
eye2 / 2110549
heart0 / 896260 
intestine3 / 23447212
kidney1 / 2117774
larynx0 / 241450 
liver0 / 2077430 
lung6 / 33697417
lymph0 / 442700 
lymph node0 / 916100 
mammary gland1 / 1532716
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary2 / 10205119
pancreas1 / 2148124
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta12 / 28082542
prostate3 / 18934515
salivary gland0 / 201550 
skin2 / 2105749
spleen6 / 53952111
stomach0 / 966190 
testis4 / 33044212
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus3 / 23287812
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_12031_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.12 ± 0.78
Basal Forebrain2.84 ± 0.68
Basal Part of Pons3 ± 0.55
Cerebellar Cortex3.52 ± 0.6
Cerebellar Nuclei3.13 ± 0.61
Claustrum3.38 ± 0.73
Epithalamus3.1 ± 0.72
Frontal Lobe3.09 ± 0.68
Globus Pallidus3.06 ± 0.48
Hypothalamus3.06 ± 0.62
Insula3.44 ± 0.57
Limbic Lobe3.11 ± 0.56
Mesencephalon3.08 ± 0.69
Myelencephalon3.15 ± 0.65
Occipital Lobe3.05 ± 0.65
Parietal Lobe3.09 ± 0.72
Pontine Tegmentum3.06 ± 0.68
Striatum2.71 ± 0.63
Subthalamus3.11 ± 0.93
Temporal Lobe3.21 ± 0.62
Thalamus3.05 ± 0.73
White Matter3.24 ± 0.86
Mouse Brain ISH
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018