AutismKB 2.0

Annotation Detail for ADPRHL2


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Basic Information Top
Gene Symbol:ADPRHL2 ( ARH3,FLJ20446 )
Gene Full Name: ADP-ribosylhydrolase like 2
Band: 1p34.3
Quick LinksEntrez ID:54936; OMIM: 610624; Uniprot ID:ARHL2_HUMAN; ENSEMBL ID: ENSG00000116863; HGNC ID: 21304
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body4 / 7076156
blastocyst0 / 623190 
fetus27 / 56401247
neonate3 / 3109796
infant0 / 236200 
juvenile7 / 55556125
adult112 / 193912157
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor3 / 9417831
cervical tumor2 / 3436658
chondrosarcoma7 / 8282384
colorectal tumor7 / 11424661
esophageal tumor0 / 172900 
gastrointestinal tumor9 / 11936975
germ cell tumor5 / 26384518
glioma9 / 10688384
head and neck tumor5 / 13630236
kidney tumor4 / 6895958
leukemia10 / 95842104
liver tumor2 / 9635920
lung tumor6 / 10312758
lymphoma17 / 71755236
non-neoplasia3 / 9725030
normal162 / 336030748
ovarian tumor2 / 7668226
pancreatic tumor10 / 10461695
primitive neuroectodermal tumor of the CNS10 / 12568079
prostate cancer1 / 1026809
retinoblastoma1 / 4635621
skin tumor13 / 124949104
soft tissue/muscle tissue tumor8 / 12519163
uterine tumor7 / 9025777
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland1 / 3319730
ascites4 / 4001599
bladder0 / 297570 
blood11 / 12347889
bone2 / 7165527
bone marrow1 / 4880120
brain57 / 110098951
cervix8 / 48171166
connective tissue6 / 14925540
ear0 / 162120 
embryonic tissue10 / 21572246
esophagus0 / 202090 
eye13 / 21105461
heart8 / 8962689
intestine15 / 23447263
kidney9 / 21177742
larynx0 / 241450 
liver7 / 20774333
lung16 / 33697447
lymph3 / 4427067
lymph node3 / 9161032
mammary gland5 / 15327132
mouth2 / 6705229
muscle2 / 10771518
nerve2 / 15768126
ovary7 / 10205168
pancreas13 / 21481260
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland1 / 1658560
placenta12 / 28082542
prostate1 / 1893455
salivary gland0 / 201550 
skin18 / 21057485
spleen1 / 5395218
stomach6 / 9661962
testis8 / 33044224
thymus3 / 8113136
thyroid5 / 47473105
tonsil2 / 16999117
trachea0 / 524130 
umbilical cord3 / 13680219
uterus17 / 23287872
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_11416_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.31 ± 0.69
Basal Forebrain4.7 ± 0.3
Basal Part of Pons5.04 ± 0.42
Cerebellar Cortex4.89 ± 0.52
Cerebellar Nuclei4.61 ± 0.42
Claustrum4.25 ± 1.15
Epithalamus5.36 ± 0.93
Frontal Lobe4.75 ± 0.61
Globus Pallidus4.61 ± 0.36
Hypothalamus4.55 ± 0.7
Insula4.75 ± 0.52
Limbic Lobe4.42 ± 0.67
Mesencephalon4.57 ± 0.67
Myelencephalon4.62 ± 0.65
Occipital Lobe3.96 ± 0.68
Parietal Lobe4.46 ± 0.66
Pontine Tegmentum4.53 ± 0.63
Striatum4.18 ± 0.5
Subthalamus4.09 ± 0.33
Temporal Lobe4.75 ± 0.62
Thalamus4.51 ± 0.53
White Matter5.78 ± 0.63
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Adprhl2CBCerebellum14.02
13.03
Adprhl2CTXCerebral cortex25.65
17.05
Adprhl2HIPHippocampal region21.8
22.22
Adprhl2HPFHippocampal formation24.16
21.59
Adprhl2HYHypothalamus6.52
4.71
Adprhl2LSXLateral septal complex9.53
6.26
Adprhl2MBMidbrain9.78
8.08
Adprhl2MYMedulla8.54
9.13
Adprhl2OLFOlfactory bulb35.28
28.15
Adprhl2PPons10.94
10.67
Adprhl2PALPallidum9.35
7.45
Adprhl2RHPRetrohippocampal region28.73
21.26
Adprhl2sAMYStriatum-like amygdalar nuclei6.7
4.34
Adprhl2STRStriatum11.53
7.51
Adprhl2STRdStriatum dorsal region10.2
6.69
Adprhl2STRvStriatum ventral region18.92
11.72
Adprhl2THThalamus17.17
12.92
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
ARHL2_HUMAN_156 16 156 171 VAGISLAYSSVQDVQK PRIDE
ARHL2_HUMAN_2 17 2 18 AAAAMAAAAGGGAGAAR PRIDE
ARHL2_HUMAN_53 16 53 68 HVQSLEPDPGTPGSER PRIDE
PAp00001333 9 132 140 CRDVFEPAR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018