AutismKB 2.0

Annotation Detail for SARS2


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Basic Information Top
Gene Symbol:SARS2 ( FLJ20450,SARS,SARSM,SERS,SYS,SerRS,SerRSmt,mtSerRS )
Gene Full Name: seryl-tRNA synthetase 2, mitochondrial
Band: 19q13.2
Quick LinksEntrez ID:54938; OMIM: 612804; Uniprot ID:SYSM_HUMAN; ENSEMBL ID: ENSG00000104835; HGNC ID: 17697
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst1 / 6231916
fetus14 / 56401224
neonate0 / 310970 
infant0 / 236200 
juvenile5 / 5555689
adult71 / 193912136
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor9 / 9417895
cervical tumor2 / 3436658
chondrosarcoma3 / 8282336
colorectal tumor2 / 11424617
esophageal tumor2 / 17290115
gastrointestinal tumor7 / 11936958
germ cell tumor4 / 26384515
glioma10 / 10688393
head and neck tumor1 / 1363027
kidney tumor1 / 6895914
leukemia12 / 95842125
liver tumor4 / 9635941
lung tumor6 / 10312758
lymphoma1 / 7175513
non-neoplasia1 / 9725010
normal99 / 336030729
ovarian tumor9 / 76682117
pancreatic tumor13 / 104616124
primitive neuroectodermal tumor of the CNS19 / 125680151
prostate cancer2 / 10268019
retinoblastoma3 / 4635664
skin tumor8 / 12494964
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor4 / 9025744
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites4 / 4001599
bladder0 / 297570 
blood14 / 123478113
bone3 / 7165541
bone marrow2 / 4880140
brain50 / 110098945
cervix4 / 4817183
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue2 / 2157229
esophagus2 / 2020998
eye6 / 21105428
heart1 / 8962611
intestine11 / 23447246
kidney6 / 21177728
larynx0 / 241450 
liver6 / 20774328
lung9 / 33697426
lymph1 / 4427022
lymph node2 / 9161021
mammary gland10 / 15327165
mouth1 / 6705214
muscle4 / 10771537
nerve0 / 157680 
ovary10 / 10205197
pancreas14 / 21481265
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta10 / 28082535
prostate2 / 18934510
salivary gland1 / 2015549
skin9 / 21057442
spleen5 / 5395292
stomach1 / 9661910
testis4 / 33044212
thymus3 / 8113136
thyroid1 / 4747321
tonsil3 / 16999176
trachea2 / 5241338
umbilical cord0 / 136800 
uterus4 / 23287817
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 218702_at
Cell line Expression level Expression bar
721_B_lymphoblasts9.75
Adipocyte4.45
AdrenalCortex4.7
Adrenalgland4
Amygdala4.7
Appendix4.65
AtrioventricularNode3.5
BDCA4+_DentriticCells5
Bonemarrow4.55
BronchialEpithelialCells4.5
CD105+_Endothelial4.6
CD14+_Monocytes4.85
CD19+_BCells(neg._sel.)4.9
CD33+_Myeloid5.75
CD34+8.15
CD4+_Tcells5.6
CD56+_NKCells5.45
CD71+_EarlyErythroid4.15
CD8+_Tcells4.65
CardiacMyocytes5.5
Caudatenucleus4.05
Cerebellum3.65
CerebellumPeduncles5.15
CiliaryGanglion3.25
CingulateCortex4.65
Colorectaladenocarcinoma4.6
DorsalRootGanglion3.5
FetalThyroid5.4
Fetalbrain4.45
Fetalliver3.9
Fetallung3.7
GlobusPallidus3.35
Heart7.95
Hypothalamus4.95
Kidney3.7
Leukemia_chronicMyelogenousK-5624.15
Leukemia_promyelocytic-HL-605.3
Leukemialymphoblastic(MOLT-4)3.65
Liver6.2
Lung5
Lymphnode3.95
Lymphoma_burkitts(Daudi)6.35
Lymphoma_burkitts(Raji)9.35
MedullaOblongata4.1
OccipitalLobe4.05
OlfactoryBulb3.6
Ovary3
Pancreas3.65
PancreaticIslet4.8
ParietalLobe4.8
Pituitary5.3
Placenta4.6
Pons4.55
PrefrontalCortex5.6
Prostate5.25
Salivarygland3.6
SkeletalMuscle5.5
Skin4.45
SmoothMuscle5.1
Spinalcord4.8
SubthalamicNucleus4.15
SuperiorCervicalGanglion5.6
TemporalLobe4.1
Testis3.85
TestisGermCell3.75
TestisIntersitial3.8
TestisLeydigCell4.4
TestisSeminiferousTubule3.9
Thalamus4.65
Thymus3.6
Thyroid7
Tongue4.4
Tonsil4.4
Trachea3.75
TrigeminalGanglion4.4
Uterus3.65
UterusCorpus4.15
WholeBlood4.95
Wholebrain3.85
colon4.55
pineal_day5.62
pineal_night5.52
retina5.475
small_intestine4.35
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_12549_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.4 ± 0.41
Basal Forebrain4.23 ± 0.22
Basal Part of Pons4.24 ± 0.36
Cerebellar Cortex4.11 ± 0.51
Cerebellar Nuclei4.26 ± 0.42
Claustrum4.78 ± 0.69
Epithalamus3.85 ± 0.44
Frontal Lobe4.17 ± 0.46
Globus Pallidus4.25 ± 0.34
Hypothalamus4.11 ± 0.36
Insula4.15 ± 0.41
Limbic Lobe4.37 ± 0.47
Mesencephalon4.19 ± 0.55
Myelencephalon4.23 ± 0.52
Occipital Lobe4.26 ± 0.54
Parietal Lobe4.38 ± 0.52
Pontine Tegmentum4.29 ± 0.51
Striatum4.18 ± 0.46
Subthalamus4.15 ± 0.39
Temporal Lobe4.29 ± 0.46
Thalamus4.13 ± 0.56
White Matter3.99 ± 0.58
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Sars2CBCerebellum44.38
70.15
Sars2CTXCerebral cortex75.17
63.63
Sars2HIPHippocampal region47.69
66.52
Sars2HPFHippocampal formation53.31
62.11
Sars2HYHypothalamus12.9
11.5
Sars2LSXLateral septal complex21.37
17.38
Sars2MBMidbrain15.49
14.72
Sars2MYMedulla37.43
43.23
Sars2OLFOlfactory bulb75.85
75.43
Sars2PPons25.32
28.92
Sars2PALPallidum30.03
33.55
Sars2RHPRetrohippocampal region64.01
56.12
Sars2sAMYStriatum-like amygdalar nuclei64.41
61.76
Sars2STRStriatum50.24
41.93
Sars2STRdStriatum dorsal region51.17
41.96
Sars2STRvStriatum ventral region48.95
38.64
Sars2THThalamus45.25
49.41
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00063643 16 119 134 ALLANQDSGEVQQDPK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018