AutismKB 2.0

Annotation Detail for PARP16


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Basic Information Top
Gene Symbol:PARP16 ( C15orf30,FLJ20509,FLJ25281,pART15 )
Gene Full Name: poly (ADP-ribose) polymerase family, member 16
Band: 15q22.31
Quick LinksEntrez ID:54956; OMIM: NA; Uniprot ID:PAR16_HUMAN; ENSEMBL ID: ENSG00000138617; HGNC ID: 26040
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst1 / 6231916
fetus31 / 56401254
neonate0 / 310970 
infant1 / 2362042
juvenile1 / 5555617
adult38 / 193912119
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor2 / 9417821
cervical tumor1 / 3436629
chondrosarcoma1 / 8282312
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor7 / 11936958
germ cell tumor6 / 26384522
glioma2 / 10688318
head and neck tumor3 / 13630222
kidney tumor1 / 6895914
leukemia2 / 9584220
liver tumor0 / 963590 
lung tumor1 / 1031279
lymphoma1 / 7175513
non-neoplasia1 / 9725010
normal86 / 336030725
ovarian tumor0 / 766820 
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS7 / 12568055
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor1 / 1249498
soft tissue/muscle tissue tumor3 / 12519123
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland1 / 3319730
ascites2 / 4001549
bladder0 / 297570 
blood5 / 12347840
bone0 / 716550 
bone marrow0 / 488010 
brain23 / 110098920
cervix1 / 4817120
connective tissue4 / 14925526
ear0 / 162120 
embryonic tissue1 / 2157224
esophagus0 / 202090 
eye6 / 21105428
heart2 / 8962622
intestine4 / 23447217
kidney6 / 21177728
larynx0 / 241450 
liver1 / 2077434
lung5 / 33697414
lymph0 / 442700 
lymph node6 / 9161065
mammary gland8 / 15327152
mouth3 / 6705244
muscle0 / 1077150 
nerve0 / 157680 
ovary1 / 1020519
pancreas2 / 2148129
parathyroid1 / 2053948
pharynx2 / 4132848
pituitary gland0 / 165850 
placenta3 / 28082510
prostate3 / 18934515
salivary gland0 / 201550 
skin4 / 21057418
spleen0 / 539520 
stomach4 / 9661941
testis7 / 33044221
thymus3 / 8113136
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus4 / 23287817
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 219034_at
Cell line Expression level Expression bar
721_B_lymphoblasts5.95
Adipocyte4.65
AdrenalCortex5.35
Adrenalgland4
Amygdala4.85
Appendix5.8
AtrioventricularNode6.35
BDCA4+_DentriticCells5.1
Bonemarrow5.05
BronchialEpithelialCells4.45
CD105+_Endothelial6.05
CD14+_Monocytes5
CD19+_BCells(neg._sel.)5.4
CD33+_Myeloid6.05
CD34+6.45
CD4+_Tcells6.5
CD56+_NKCells5.9
CD71+_EarlyErythroid4.65
CD8+_Tcells5.8
CardiacMyocytes5.75
Caudatenucleus4.2
Cerebellum3.85
CerebellumPeduncles5.25
CiliaryGanglion4.65
CingulateCortex4.85
Colorectaladenocarcinoma4.75
DorsalRootGanglion5.1
FetalThyroid4.6
Fetalbrain4.75
Fetalliver4.25
Fetallung3.9
GlobusPallidus3.45
Heart5.8
Hypothalamus5.05
Kidney3.75
Leukemia_chronicMyelogenousK-5624.3
Leukemia_promyelocytic-HL-604.15
Leukemialymphoblastic(MOLT-4)4.85
Liver6.1
Lung5.25
Lymphnode4.3
Lymphoma_burkitts(Daudi)6.1
Lymphoma_burkitts(Raji)5.95
MedullaOblongata4.35
OccipitalLobe4.25
OlfactoryBulb3.7
Ovary3.2
Pancreas3.8
PancreaticIslet5.05
ParietalLobe4.9
Pituitary5.6
Placenta4.8
Pons4.5
PrefrontalCortex5.8
Prostate5.6
Salivarygland4.55
SkeletalMuscle5.65
Skin5.6
SmoothMuscle5.3
Spinalcord5.2
SubthalamicNucleus4.65
SuperiorCervicalGanglion5.95
TemporalLobe4.3
Testis4.5
TestisGermCell4
TestisIntersitial4
TestisLeydigCell4.7
TestisSeminiferousTubule4.1
Thalamus4.8
Thymus3.8
Thyroid5.85
Tongue4.6
Tonsil4.55
Trachea3.95
TrigeminalGanglion4.95
Uterus3.9
UterusCorpus4.15
WholeBlood5.2
Wholebrain3.85
colon4.75
pineal_day5.8
pineal_night5.72
retina5.975
small_intestine4.6
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_8118_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.07 ± 1.01
Basal Forebrain2.99 ± 0.29
Basal Part of Pons2.44 ± 0.69
Cerebellar Cortex2.98 ± 0.49
Cerebellar Nuclei2.72 ± 0.59
Claustrum3.31 ± 0.73
Epithalamus2.69 ± 0.87
Frontal Lobe2.54 ± 0.79
Globus Pallidus3.13 ± 0.72
Hypothalamus2.52 ± 0.65
Insula2.74 ± 0.72
Limbic Lobe2.8 ± 0.71
Mesencephalon2.93 ± 0.79
Myelencephalon2.76 ± 0.74
Occipital Lobe2.78 ± 0.75
Parietal Lobe2.7 ± 0.71
Pontine Tegmentum2.73 ± 0.71
Striatum2.75 ± 0.98
Subthalamus2.68 ± 0.61
Temporal Lobe2.72 ± 0.75
Thalamus2.67 ± 0.7
White Matter2.89 ± 0.8
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Parp16CBCerebellum0.76
0.92
Parp16CTXCerebral cortex0.57
0.5
Parp16HIPHippocampal region0.79
0.84
Parp16HPFHippocampal formation0.61
0.59
Parp16HYHypothalamus0.05
0.05
Parp16LSXLateral septal complex0.05
0
Parp16MBMidbrain0.7
0.65
Parp16MYMedulla5.18
6.52
Parp16OLFOlfactory bulb1.41
1.17
Parp16PPons1.2
1.23
Parp16PALPallidum0.47
0.42
Parp16RHPRetrohippocampal region0.29
0.19
Parp16sAMYStriatum-like amygdalar nuclei0.45
0.27
Parp16STRStriatum0.4
0.41
Parp16STRdStriatum dorsal region0.42
0.53
Parp16STRvStriatum ventral region0.39
0.22
Parp16THThalamus0.61
0.71
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00041676 27 111 137 LTGAPHTPVPAPDFLFEIEYFDPANAK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018