AutismKB 2.0

Annotation Detail for ULK4


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Basic Information Top
Gene Symbol:ULK4 ( DKFZp434E1822,FAM7C1,FLJ20574,REC01035 )
Gene Full Name: unc-51-like kinase 4 (C. elegans)
Band: 3p22.1
Quick LinksEntrez ID:54986; OMIM: NA; Uniprot ID:ULK4_HUMAN; ENSEMBL ID: ENSG00000168038; HGNC ID: 15784
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst0 / 623190 
fetus14 / 56401224
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult42 / 193912121
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor2 / 11424617
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor5 / 26384518
glioma0 / 1068830 
head and neck tumor1 / 1363027
kidney tumor0 / 689590 
leukemia2 / 9584220
liver tumor1 / 9635910
lung tumor1 / 1031279
lymphoma1 / 7175513
non-neoplasia0 / 972500 
normal84 / 336030724
ovarian tumor2 / 7668226
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor6 / 12494948
soft tissue/muscle tissue tumor7 / 12519155
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood1 / 1234788
bone1 / 7165513
bone marrow3 / 4880161
brain12 / 110098910
cervix0 / 481710 
connective tissue7 / 14925546
ear0 / 162120 
embryonic tissue4 / 21572218
esophagus0 / 202090 
eye0 / 2110540 
heart1 / 8962611
intestine2 / 2344728
kidney5 / 21177723
larynx0 / 241450 
liver3 / 20774314
lung5 / 33697414
lymph1 / 4427022
lymph node4 / 9161043
mammary gland2 / 15327113
mouth1 / 6705214
muscle1 / 1077159
nerve0 / 157680 
ovary2 / 10205119
pancreas2 / 2148129
parathyroid0 / 205390 
pharynx2 / 4132848
pituitary gland0 / 165850 
placenta2 / 2808257
prostate4 / 18934521
salivary gland0 / 201550 
skin8 / 21057437
spleen2 / 5395237
stomach2 / 9661920
testis38 / 330442114
thymus1 / 8113112
thyroid0 / 474730 
tonsil0 / 169990 
trachea4 / 5241376
umbilical cord0 / 136800 
uterus9 / 23287838
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 220958_at
Cell line Expression level Expression bar
721_B_lymphoblasts4.6
Adipocyte3.6
AdrenalCortex3.85
Adrenalgland3.15
Amygdala3.85
Appendix4.05
AtrioventricularNode4.45
BDCA4+_DentriticCells4.05
Bonemarrow3.75
BronchialEpithelialCells3.6
CD105+_Endothelial3.75
CD14+_Monocytes3.85
CD19+_BCells(neg._sel.)3.9
CD33+_Myeloid4.7
CD34+4.55
CD4+_Tcells4
CD56+_NKCells4.3
CD71+_EarlyErythroid3.45
CD8+_Tcells3.55
CardiacMyocytes5.05
Caudatenucleus3.45
Cerebellum3
CerebellumPeduncles5.6
CiliaryGanglion3.3
CingulateCortex3.75
Colorectaladenocarcinoma3.7
DorsalRootGanglion3.7
FetalThyroid3.6
Fetalbrain3.7
Fetalliver3.2
Fetallung3.05
GlobusPallidus2.85
Heart5.05
Hypothalamus4.05
Kidney3
Leukemia_chronicMyelogenousK-5623.35
Leukemia_promyelocytic-HL-603.2
Leukemialymphoblastic(MOLT-4)2.9
Liver5
Lung4
Lymphnode3.15
Lymphoma_burkitts(Daudi)4.7
Lymphoma_burkitts(Raji)5.25
MedullaOblongata3.6
OccipitalLobe3.25
OlfactoryBulb2.95
Ovary2.75
Pancreas3
PancreaticIslet3.95
ParietalLobe4
Pituitary4.25
Placenta3.8
Pons3.65
PrefrontalCortex4.55
Prostate4.3
Salivarygland2.95
SkeletalMuscle5.35
Skin3.15
SmoothMuscle4.15
Spinalcord3.95
SubthalamicNucleus3.4
SuperiorCervicalGanglion4.3
TemporalLobe3.4
Testis3.25
TestisGermCell3.05
TestisIntersitial4.2
TestisLeydigCell4
TestisSeminiferousTubule3.35
Thalamus3.75
Thymus2.9
Thyroid4.6
Tongue3.7
Tonsil3.55
Trachea3.05
TrigeminalGanglion4.25
Uterus3.05
UterusCorpus3.5
WholeBlood4
Wholebrain3.15
colon3.7
pineal_day4.52
pineal_night4.46
retina4.9
small_intestine3.5
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P254680
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.3 ± 0.8
Basal Forebrain2.56 ± 0.44
Basal Part of Pons2.52 ± 0.41
Cerebellar Cortex2.55 ± 0.65
Cerebellar Nuclei2.98 ± 0.72
Claustrum3.27 ± 0.7
Epithalamus4.61 ± 1.15
Frontal Lobe2.95 ± 0.81
Globus Pallidus2.59 ± 0.42
Hypothalamus2.8 ± 0.62
Insula3.11 ± 0.7
Limbic Lobe3.05 ± 0.67
Mesencephalon3.1 ± 0.81
Myelencephalon2.99 ± 0.8
Occipital Lobe2.96 ± 0.81
Parietal Lobe2.91 ± 0.74
Pontine Tegmentum2.96 ± 0.66
Striatum3.17 ± 1
Subthalamus2.84 ± 0.59
Temporal Lobe2.97 ± 0.77
Thalamus2.73 ± 0.63
White Matter2.49 ± 0.41
Mouse Brain ISH
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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