AutismKB 2.0

Annotation Detail for MOSC2


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Basic Information Top
Gene Symbol:MOSC2 ( FLJ20605,RP11-270A6.1 )
Gene Full Name: MOCO sulphurase C-terminal domain containing 2
Band: 1q41
Quick LinksEntrez ID:54996; OMIM: NA; Uniprot ID:MOSC2_HUMAN; ENSEMBL ID: ENSG00000117791; HGNC ID:
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus13 / 56401223
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult48 / 193912124
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor2 / 9417821
cervical tumor1 / 3436629
chondrosarcoma0 / 828230 
colorectal tumor3 / 11424626
esophageal tumor0 / 172900 
gastrointestinal tumor2 / 11936916
germ cell tumor4 / 26384515
glioma3 / 10688328
head and neck tumor0 / 1363020 
kidney tumor2 / 6895929
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia1 / 9725010
normal88 / 336030726
ovarian tumor0 / 766820 
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland0 / 331970 
ascites1 / 4001524
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain11 / 11009899
cervix1 / 4817120
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye1 / 2110544
heart0 / 896260 
intestine5 / 23447221
kidney32 / 211777151
larynx0 / 241450 
liver3 / 20774314
lung5 / 33697414
lymph0 / 442700 
lymph node0 / 916100 
mammary gland2 / 15327113
mouth0 / 670520 
muscle1 / 1077159
nerve0 / 157680 
ovary2 / 10205119
pancreas2 / 2148129
parathyroid8 / 20539389
pharynx12 / 41328290
pituitary gland0 / 165850 
placenta2 / 2808257
prostate6 / 18934531
salivary gland0 / 201550 
skin0 / 2105740 
spleen3 / 5395255
stomach2 / 9661920
testis4 / 33044212
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus1 / 2328784
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 221636_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts17.85
Adipocyte32.6
AdrenalCortex10.65
Adrenalgland15.95
Amygdala26.4
Appendix11.55
AtrioventricularNode8.4
BDCA4+_DentriticCells6.6
Bonemarrow10
BronchialEpithelialCells8.75
CD105+_Endothelial10.1
CD14+_Monocytes7.6
CD19+_BCells(neg._sel.)16.95
CD33+_Myeloid10.9
CD34+10.9
CD4+_Tcells9.7
CD56+_NKCells11.65
CD71+_EarlyErythroid9.55
CD8+_Tcells9.05
CardiacMyocytes14.95
Caudatenucleus9.55
Cerebellum8.75
CerebellumPeduncles11.3
CiliaryGanglion7.7
CingulateCortex12.45
Colorectaladenocarcinoma10.85
DorsalRootGanglion15.95
FetalThyroid25.3
Fetalbrain12.8
Fetalliver39.55
Fetallung39.3
GlobusPallidus7.65
Heart15
Hypothalamus17.25
Kidney197.7
Leukemia_chronicMyelogenousK-56213.7
Leukemia_promyelocytic-HL-609.05
Leukemialymphoblastic(MOLT-4)5.85
Liver193.4
Lung26.1
Lymphnode10.1
Lymphoma_burkitts(Daudi)12.85
Lymphoma_burkitts(Raji)11.35
MedullaOblongata10.1
OccipitalLobe9.7
OlfactoryBulb8.35
Ovary7.45
Pancreas7.9
PancreaticIslet11.45
ParietalLobe10.9
Pituitary13.05
Placenta12.6
Pons10.4
PrefrontalCortex12.8
Prostate13.85
Salivarygland23.6
SkeletalMuscle12.85
Skin10.45
SmoothMuscle7.75
Spinalcord11.1
SubthalamicNucleus9.5
SuperiorCervicalGanglion13.2
TemporalLobe9.95
Testis9.35
TestisGermCell11.3
TestisIntersitial10.25
TestisLeydigCell10.9
TestisSeminiferousTubule15.7
Thalamus10.5
Thymus7.85
Thyroid185.5
Tongue10.25
Tonsil9.85
Trachea15.05
TrigeminalGanglion19.35
Uterus9
UterusCorpus12.7
WholeBlood9.05
Wholebrain9.55
colon29.75
pineal_day18.68
pineal_night21.3
retina17.25
small_intestine105.25
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_7179_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.04 ± 0.38
Basal Forebrain4.88 ± 0.42
Basal Part of Pons4.02 ± 0.35
Cerebellar Cortex4.29 ± 0.37
Cerebellar Nuclei4.29 ± 0.34
Claustrum4.95 ± 0.73
Epithalamus5.22 ± 0.32
Frontal Lobe4.82 ± 0.47
Globus Pallidus5.62 ± 0.18
Hypothalamus4.8 ± 0.67
Insula4.77 ± 0.42
Limbic Lobe4.72 ± 0.47
Mesencephalon4.95 ± 0.54
Myelencephalon4.8 ± 0.53
Occipital Lobe4.9 ± 0.39
Parietal Lobe4.78 ± 0.49
Pontine Tegmentum4.96 ± 0.43
Striatum5.11 ± 0.36
Subthalamus4.53 ± 0.32
Temporal Lobe4.73 ± 0.44
Thalamus5.05 ± 0.51
White Matter3.56 ± 0.59
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Mosc2CBCerebellum0.07
0.33
Mosc2CTXCerebral cortex2
1.75
Mosc2HIPHippocampal region0.9
0.82
Mosc2HPFHippocampal formation0.55
0.48
Mosc2HYHypothalamus0.03
0.09
Mosc2LSXLateral septal complex0.55
0.54
Mosc2MBMidbrain0.07
0.25
Mosc2MYMedulla0
0
Mosc2OLFOlfactory bulb2
2.34
Mosc2PPons0
0
Mosc2PALPallidum0.03
0.02
Mosc2RHPRetrohippocampal region0.06
0.1
Mosc2sAMYStriatum-like amygdalar nuclei0.03
0
Mosc2STRStriatum0.25
0.26
Mosc2STRdStriatum dorsal region0.3
0.3
Mosc2STRvStriatum ventral region0.06
0.04
Mosc2THThalamus0.03
0.01
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00001080 15 272 286 CILTTVDPDTGVIDR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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