AutismKB 2.0

Annotation Detail for TESC


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Basic Information Top
Gene Symbol:TESC ( CHP3,FLJ20607,TSC )
Gene Full Name: tescalcin
Band: 12q24.22
Quick LinksEntrez ID:54997; OMIM: 611585; Uniprot ID:TESC_HUMAN; ENSEMBL ID: ENSG00000088992; HGNC ID: 26065
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus18 / 56401231
neonate0 / 310970 
infant0 / 236200 
juvenile2 / 5555635
adult46 / 193912123
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor6 / 11424652
esophageal tumor0 / 172900 
gastrointestinal tumor10 / 11936983
germ cell tumor0 / 2638450 
glioma2 / 10688318
head and neck tumor5 / 13630236
kidney tumor0 / 689590 
leukemia8 / 9584283
liver tumor1 / 9635910
lung tumor17 / 103127164
lymphoma5 / 7175569
non-neoplasia0 / 972500 
normal56 / 336030716
ovarian tumor3 / 7668239
pancreatic tumor5 / 10461647
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer1 / 1026809
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites4 / 4001599
bladder0 / 297570 
blood4 / 12347832
bone1 / 7165513
bone marrow0 / 488010 
brain8 / 11009897
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye3 / 21105414
heart4 / 8962644
intestine14 / 23447259
kidney0 / 2117770 
larynx0 / 241450 
liver1 / 2077434
lung25 / 33697474
lymph5 / 44270112
lymph node1 / 9161010
mammary gland0 / 1532710 
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary2 / 10205119
pancreas6 / 21481227
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland2 / 16585120
placenta3 / 28082510
prostate7 / 18934536
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach10 / 96619103
testis9 / 33044227
thymus0 / 811310 
thyroid5 / 47473105
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus1 / 2328784
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 218872_at
Cell line Expression level Expression bar
721_B_lymphoblasts12.2
Adipocyte8.45
AdrenalCortex13.35
Adrenalgland12.5
Amygdala13.35
Appendix7.45
AtrioventricularNode6.8
BDCA4+_DentriticCells9.5
Bonemarrow55.4
BronchialEpithelialCells6.75
CD105+_Endothelial246.05
CD14+_Monocytes123.15
CD19+_BCells(neg._sel.)12.1
CD33+_Myeloid113.4
CD34+48.8
CD4+_Tcells8.35
CD56+_NKCells44.45
CD71+_EarlyErythroid414.25
CD8+_Tcells8.7
CardiacMyocytes6.6
Caudatenucleus42.4
Cerebellum7
CerebellumPeduncles10.2
CiliaryGanglion6.8
CingulateCortex9.4
Colorectaladenocarcinoma5.15
DorsalRootGanglion5.65
FetalThyroid8.85
Fetalbrain8.15
Fetalliver20.65
Fetallung8.45
GlobusPallidus6.65
Heart37.3
Hypothalamus6.85
Kidney7.45
Leukemia_chronicMyelogenousK-56242.35
Leukemia_promyelocytic-HL-6010.45
Leukemialymphoblastic(MOLT-4)36.15
Liver10.1
Lung12.45
Lymphnode7.6
Lymphoma_burkitts(Daudi)11.6
Lymphoma_burkitts(Raji)66.35
MedullaOblongata18.45
OccipitalLobe8.05
OlfactoryBulb4.5
Ovary6.15
Pancreas37.15
PancreaticIslet26.2
ParietalLobe9.85
Pituitary10.75
Placenta9.3
Pons15.7
PrefrontalCortex11.35
Prostate27.05
Salivarygland33.45
SkeletalMuscle11
Skin4.3
SmoothMuscle8.1
Spinalcord8.5
SubthalamicNucleus7.95
SuperiorCervicalGanglion11.85
TemporalLobe33.1
Testis13.9
TestisGermCell10.8
TestisIntersitial9.15
TestisLeydigCell18.35
TestisSeminiferousTubule10.4
Thalamus8.5
Thymus7.15
Thyroid12.6
Tongue8.9
Tonsil8.55
Trachea9.3
TrigeminalGanglion13.7
Uterus5.9
UterusCorpus8.05
WholeBlood21.4
Wholebrain17.7
colon6.05
pineal_day10.26
pineal_night8.62
retina7.95
small_intestine6
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_5903_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.24 ± 0.81
Basal Forebrain6.96 ± 0.48
Basal Part of Pons8.19 ± 0.31
Cerebellar Cortex6.46 ± 0.44
Cerebellar Nuclei7.43 ± 0.9
Claustrum7.9 ± 0.44
Epithalamus6.62 ± 0.58
Frontal Lobe7.55 ± 0.6
Globus Pallidus6.34 ± 0.99
Hypothalamus6.73 ± 0.49
Insula7.13 ± 0.49
Limbic Lobe7.49 ± 0.99
Mesencephalon6.85 ± 0.61
Myelencephalon7.24 ± 0.88
Occipital Lobe6.46 ± 0.76
Parietal Lobe7.35 ± 0.63
Pontine Tegmentum7.14 ± 0.58
Striatum9 ± 0.51
Subthalamus7.15 ± 0.58
Temporal Lobe7.25 ± 0.53
Thalamus6.6 ± 0.52
White Matter5.22 ± 0.54
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
TescCBCerebellum84.42
100
TescCTXCerebral cortex70.9
78.26
TescHIPHippocampal region67.02
100
TescHPFHippocampal formation62.45
95.67
TescHYHypothalamus6.41
6.35
TescLSXLateral septal complex17.25
16.01
TescMBMidbrain19.73
25.41
TescMYMedulla42.12
68.25
TescOLFOlfactory bulb61.54
75.1
TescPPons30.82
47.2
TescPALPallidum21.38
25.43
TescRHPRetrohippocampal region55.27
68.61
TescsAMYStriatum-like amygdalar nuclei33.73
30.53
TescSTRStriatum100
100
TescSTRdStriatum dorsal region100
100
TescSTRvStriatum ventral region100
100
TescTHThalamus14.66
18.84
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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