Annotation Detail for PHIP
Basic Information Top
| Gene Symbol: | PHIP ( DCAF14,FLJ20705,FLJ45918,MGC90216,WDR11,ndrp ) |
|---|---|
| Gene Full Name: | pleckstrin homology domain interacting protein |
| Band: | 6q14.1 |
| Quick Links | Entrez ID:55023; OMIM: 612870; Uniprot ID:PHIP_HUMAN; ENSEMBL ID: ENSG00000146247; HGNC ID: 15673 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.606356
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 8 / 70761 | 113 |  |
| blastocyst | 8 / 62319 | 128 | |
| fetus | 59 / 564012 | 104 | |
| neonate | 1 / 31097 | 32 |  |
| infant | 2 / 23620 | 84 | |
| juvenile | 5 / 55556 | 89 | |
| adult | 124 / 1939121 | 63 | |
| embryoid body | 0 / 70761 | 0 | |
| blastocyst | 0 / 62319 | 0 | |
| fetus | 4 / 564012 | 7 |  |
| neonate | 0 / 31097 | 0 | |
| infant | 0 / 23620 | 0 | |
| juvenile | 0 / 55556 | 0 | |
| adult | 4 / 1939121 | 2 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 1 / 12794 | 78 | |
| bladder carcinoma | 1 / 17475 | 57 | |
| breast (mammary gland) tumor | 10 / 94178 | 106 | |
| cervical tumor | 1 / 34366 | 29 | |
| chondrosarcoma | 3 / 82823 | 36 | |
| colorectal tumor | 5 / 114246 | 43 | |
| esophageal tumor | 0 / 17290 | 0 | |
| gastrointestinal tumor | 9 / 119369 | 75 | |
| germ cell tumor | 15 / 263845 | 56 | |
| glioma | 2 / 106883 | 18 | |
| head and neck tumor | 9 / 136302 | 66 | |
| kidney tumor | 3 / 68959 | 43 | |
| leukemia | 10 / 95842 | 104 | |
| liver tumor | 7 / 96359 | 72 | |
| lung tumor | 2 / 103127 | 19 | |
| lymphoma | 1 / 71755 | 13 | |
| non-neoplasia | 3 / 97250 | 30 | |
| normal | 242 / 3360307 | 72 | |
| ovarian tumor | 12 / 76682 | 156 | |
| pancreatic tumor | 4 / 104616 | 38 | |
| primitive neuroectodermal tumor of the CNS | 3 / 125680 | 23 | |
| prostate cancer | 4 / 102680 | 38 | |
| retinoblastoma | 4 / 46356 | 86 | |
| skin tumor | 8 / 124949 | 64 | |
| soft tissue/muscle tissue tumor | 7 / 125191 | 55 | |
| uterine tumor | 7 / 90257 | 77 | |
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 0 / 17475 | 0 | |
| breast (mammary gland) tumor | 0 / 94178 | 0 | |
| cervical tumor | 0 / 34366 | 0 | |
| chondrosarcoma | 0 / 82823 | 0 | |
| colorectal tumor | 0 / 114246 | 0 | |
| esophageal tumor | 0 / 17290 | 0 | |
| gastrointestinal tumor | 0 / 119369 | 0 | |
| germ cell tumor | 0 / 263845 | 0 | |
| glioma | 0 / 106883 | 0 | |
| head and neck tumor | 1 / 136302 | 7 | |
| kidney tumor | 0 / 68959 | 0 | |
| leukemia | 0 / 95842 | 0 | |
| liver tumor | 0 / 96359 | 0 | |
| lung tumor | 0 / 103127 | 0 | |
| lymphoma | 0 / 71755 | 0 | |
| non-neoplasia | 0 / 97250 | 0 | |
| normal | 11 / 3360307 | 3 | |
| ovarian tumor | 0 / 76682 | 0 | |
| pancreatic tumor | 0 / 104616 | 0 | |
| primitive neuroectodermal tumor of the CNS | 0 / 125680 | 0 | |
| prostate cancer | 0 / 102680 | 0 | |
| retinoblastoma | 0 / 46356 | 0 | |
| skin tumor | 0 / 124949 | 0 | |
| soft tissue/muscle tissue tumor | 0 / 125191 | 0 | |
| uterine tumor | 0 / 90257 | 0 |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 2 / 13106 | 152 | |
| adrenal gland | 3 / 33197 | 90 | |
| ascites | 5 / 40015 | 124 | |
| bladder | 4 / 29757 | 134 | |
| blood | 6 / 123478 | 48 | |
| bone | 2 / 71655 | 27 | |
| bone marrow | 5 / 48801 | 102 | |
| brain | 42 / 1100989 | 38 | |
| cervix | 1 / 48171 | 20 | |
| connective tissue | 5 / 149255 | 33 | |
| ear | 16 / 16212 | 986 |  |
| embryonic tissue | 27 / 215722 | 125 | |
| esophagus | 0 / 20209 | 0 | |
| eye | 19 / 211054 | 90 | |
| heart | 0 / 89626 | 0 | |
| intestine | 17 / 234472 | 72 | |
| kidney | 15 / 211777 | 70 | |
| larynx | 1 / 24145 | 41 | |
| liver | 24 / 207743 | 115 | |
| lung | 23 / 336974 | 68 | |
| lymph | 1 / 44270 | 22 | |
| lymph node | 11 / 91610 | 120 | |
| mammary gland | 21 / 153271 | 137 | |
| mouth | 6 / 67052 | 89 | |
| muscle | 15 / 107715 | 139 | |
| nerve | 2 / 15768 | 126 | |
| ovary | 12 / 102051 | 117 | |
| pancreas | 13 / 214812 | 60 | |
| parathyroid | 3 / 20539 | 146 | |
| pharynx | 2 / 41328 | 48 | |
| pituitary gland | 1 / 16585 | 60 | |
| placenta | 18 / 280825 | 64 | |
| prostate | 11 / 189345 | 58 | |
| salivary gland | 1 / 20155 | 49 | |
| skin | 9 / 210574 | 42 | |
| spleen | 4 / 53952 | 74 | |
| stomach | 0 / 96619 | 0 | |
| testis | 11 / 330442 | 33 | |
| thymus | 10 / 81131 | 123 | |
| thyroid | 4 / 47473 | 84 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 0 / 52413 | 0 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 17 / 232878 | 72 | |
| vascular | 2 / 51780 | 38 | |
| adipose tissue | 0 / 13106 | 0 | |
| adrenal gland | 0 / 33197 | 0 | |
| ascites | 0 / 40015 | 0 | |
| bladder | 0 / 29757 | 0 | |
| blood | 0 / 123478 | 0 | |
| bone | 0 / 71655 | 0 | |
| bone marrow | 0 / 48801 | 0 | |
| brain | 5 / 1100989 | 4 | |
| cervix | 0 / 48171 | 0 | |
| connective tissue | 0 / 149255 | 0 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 0 / 215722 | 0 | |
| esophagus | 0 / 20209 | 0 | |
| eye | 0 / 211054 | 0 | |
| heart | 0 / 89626 | 0 | |
| intestine | 0 / 234472 | 0 | |
| kidney | 1 / 211777 | 4 | |
| larynx | 0 / 24145 | 0 | |
| liver | 0 / 207743 | 0 | |
| lung | 0 / 336974 | 0 | |
| lymph | 0 / 44270 | 0 | |
| lymph node | 0 / 91610 | 0 | |
| mammary gland | 0 / 153271 | 0 | |
| mouth | 0 / 67052 | 0 | |
| muscle | 3 / 107715 | 27 | |
| nerve | 0 / 15768 | 0 | |
| ovary | 0 / 102051 | 0 | |
| pancreas | 0 / 214812 | 0 | |
| parathyroid | 0 / 20539 | 0 | |
| pharynx | 0 / 41328 | 0 | |
| pituitary gland | 1 / 16585 | 60 | |
| placenta | 0 / 280825 | 0 | |
| prostate | 0 / 189345 | 0 | |
| salivary gland | 0 / 20155 | 0 | |
| skin | 0 / 210574 | 0 | |
| spleen | 0 / 53952 | 0 | |
| stomach | 0 / 96619 | 0 | |
| testis | 0 / 330442 | 0 | |
| thymus | 0 / 81131 | 0 | |
| thyroid | 0 / 47473 | 0 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 0 / 52413 | 0 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 0 / 232878 | 0 | |
| vascular | 0 / 51780 | 0 |
- Microarray Platform: GeneAtlas U133A, gcrma
- Affymatrix Probe ID: 212542_s_at
| Cell line | Expression level | Expression bar |
|---|---|---|
| ||
| 721_B_lymphoblasts | 49.8 | |
| Adipocyte | 8.6 | |
| AdrenalCortex | 9.65 | |
| Adrenalgland | 7.35 | |
| Amygdala | 8.7 | |
| Appendix | 14.9 | |
| AtrioventricularNode | 10.7 | |
| BDCA4+_DentriticCells | 44.15 | |
| Bonemarrow | 9.1 | |
| BronchialEpithelialCells | 8.35 | |
| CD105+_Endothelial | 24.7 | |
| CD14+_Monocytes | 41.6 | |
| CD19+_BCells(neg._sel.) | 70.25 | |
| CD33+_Myeloid | 110.55 | |
| CD34+ | 94.05 | |
| CD4+_Tcells | 87 | |
| CD56+_NKCells | 36.7 | |
| CD71+_EarlyErythroid | 28.75 | |
| CD8+_Tcells | 63.6 | |
| CardiacMyocytes | 22.3 | |
| Caudatenucleus | 6.6 | |
| Cerebellum | 6.9 | |
| CerebellumPeduncles | 12.7 | |
| CiliaryGanglion | 8.55 | |
| CingulateCortex | 10.45 | |
| Colorectaladenocarcinoma | 8.8 | |
| DorsalRootGanglion | 9.35 | |
| FetalThyroid | 10.75 | |
| Fetalbrain | 8.75 | |
| Fetalliver | 9.15 | |
| Fetallung | 10.05 | |
| GlobusPallidus | 7.7 | |
| Heart | 12.85 | |
| Hypothalamus | 8.95 | |
| Kidney | 7.35 | |
| Leukemia_chronicMyelogenousK-562 | 8.25 | |
| Leukemia_promyelocytic-HL-60 | 9.25 | |
| Leukemialymphoblastic(MOLT-4) | 10.15 | |
| Liver | 13.35 | |
| Lung | 7.65 | |
| Lymphnode | 6.55 | |
| Lymphoma_burkitts(Daudi) | 25.8 | |
| Lymphoma_burkitts(Raji) | 15.45 | |
| MedullaOblongata | 9.5 | |
| OccipitalLobe | 13.7 | |
| OlfactoryBulb | 12.8 | |
| Ovary | 10.8 | |
| Pancreas | 8.75 | |
| PancreaticIslet | 18 | |
| ParietalLobe | 12.9 | |
| Pituitary | 42.95 | |
| Placenta | 7.35 | |
| Pons | 9.1 | |
| PrefrontalCortex | 29.65 | |
| Prostate | 9.5 | |
| Salivarygland | 7.95 | |
| SkeletalMuscle | 15.45 | |
| Skin | 8.6 | |
| SmoothMuscle | 9.85 | |
| Spinalcord | 8.3 | |
| SubthalamicNucleus | 9.9 | |
| SuperiorCervicalGanglion | 14.8 | |
| TemporalLobe | 10.35 | |
| Testis | 6.15 | |
| TestisGermCell | 20.45 | |
| TestisIntersitial | 12.25 | |
| TestisLeydigCell | 9.65 | |
| TestisSeminiferousTubule | 11.35 | |
| Thalamus | 8.45 | |
| Thymus | 5.7 | |
| Thyroid | 10.75 | |
| Tongue | 10.45 | |
| Tonsil | 12.55 | |
| Trachea | 17.35 | |
| TrigeminalGanglion | 10.5 | |
| Uterus | 30.95 | |
| UterusCorpus | 12.45 | |
| WholeBlood | 16.2 | |
| Wholebrain | 6.05 | |
| colon | 7.9 | |
| pineal_day | 94.82 | |
| pineal_night | 60.24 | |
| retina | 11.45 | |
| small_intestine | 7.25 | |
- Probe name: A_24_P630039
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 4.7 ± 0.57 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 4.72 ± 0.39 | |
| Basal Part of Pons | 4.54 ± 0.41 | |
| Cerebellar Cortex | 5 ± 0.21 | |
| Cerebellar Nuclei | 4.41 ± 0.45 | |
| Claustrum | 4.23 ± 0.66 | |
| Epithalamus | 5.02 ± 0.47 | |
| Frontal Lobe | 4.42 ± 0.5 | |
| Globus Pallidus | 4.69 ± 0.53 | |
| Hypothalamus | 4.56 ± 0.48 | |
| Insula | 4.53 ± 0.5 | |
| Limbic Lobe | 4.34 ± 0.51 | |
| Mesencephalon | 4.63 ± 0.41 | |
| Myelencephalon | 4.54 ± 0.51 | |
| Occipital Lobe | 4.75 ± 0.38 | |
| Parietal Lobe | 4.56 ± 0.47 | |
| Pontine Tegmentum | 4.44 ± 0.46 | |
| Striatum | 4.23 ± 0.51 | |
| Subthalamus | 4.12 ± 0.22 | |
| Temporal Lobe | 4.43 ± 0.49 | |
| Thalamus | 4.42 ± 0.54 | |
| White Matter | 5.51 ± 0.29 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Phip | CB | Cerebellum | 0 | |
| 0 | | |||
| Phip | CTX | Cerebral cortex | 0 | |
| 0 | | |||
| Phip | HIP | Hippocampal region | 0 | |
| 0 | | |||
| Phip | HPF | Hippocampal formation | 0 | |
| 0 | | |||
| Phip | HY | Hypothalamus | 0 | |
| 0 | | |||
| Phip | LSX | Lateral septal complex | 0 | |
| 0 | | |||
| Phip | MB | Midbrain | 0 | |
| 0 | | |||
| Phip | MY | Medulla | 0 | |
| 0 | | |||
| Phip | OLF | Olfactory bulb | 0 | |
| 0 | | |||
| Phip | P | Pons | 0 | |
| 0 | | |||
| Phip | PAL | Pallidum | 0 | |
| 0 | | |||
| Phip | RHP | Retrohippocampal region | 0 | |
| 0 | | |||
| Phip | sAMY | Striatum-like amygdalar nuclei | 0 | |
| 0 | | |||
| Phip | STR | Striatum | 0 | |
| 0 | | |||
| Phip | STRd | Striatum dorsal region | 0 | |
| 0 | | |||
| Phip | STRv | Striatum ventral region | 0 | |
| 0 | | |||
| Phip | TH | Thalamus | 0 | |
| 0 | |
| Peptide Name | Peptide Lengh | Peptide Start | Peptide End | Peptide Sequence | Source |
|---|---|---|---|---|---|
| PAp00067427 | 16 | 22 | 37 | FLEDGPCQQAAQVLIR | Peptide Atlas |