AutismKB 2.0

Annotation Detail for NOL8


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Basic Information Top
Gene Symbol:NOL8 ( C9orf34,DKFZp686P12242,FLJ20736,Nop132,bA62C3.3,bA62C3.4 )
Gene Full Name: nucleolar protein 8
Band: 9q22.31
Quick LinksEntrez ID:55035; OMIM: 611534; Uniprot ID:NOL8_HUMAN; ENSEMBL ID: ENSG00000198000; HGNC ID: 23387
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body6 / 7076184
blastocyst1 / 6231916
fetus16 / 56401228
neonate1 / 3109732
infant3 / 23620127
juvenile3 / 5555653
adult98 / 193912150
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor4 / 9417842
cervical tumor1 / 3436629
chondrosarcoma7 / 8282384
colorectal tumor7 / 11424661
esophageal tumor0 / 172900 
gastrointestinal tumor4 / 11936933
germ cell tumor15 / 26384556
glioma1 / 1068839
head and neck tumor9 / 13630266
kidney tumor2 / 6895929
leukemia7 / 9584273
liver tumor3 / 9635931
lung tumor2 / 10312719
lymphoma0 / 717550 
non-neoplasia6 / 9725061
normal114 / 336030733
ovarian tumor2 / 7668226
pancreatic tumor3 / 10461628
primitive neuroectodermal tumor of the CNS6 / 12568047
prostate cancer4 / 10268038
retinoblastoma3 / 4635664
skin tumor1 / 1249498
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor8 / 9025788
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites2 / 4001549
bladder0 / 297570 
blood3 / 12347824
bone2 / 7165527
bone marrow0 / 488010 
brain26 / 110098923
cervix1 / 4817120
connective tissue11 / 14925573
ear0 / 162120 
embryonic tissue10 / 21572246
esophagus0 / 202090 
eye8 / 21105437
heart3 / 8962633
intestine10 / 23447242
kidney7 / 21177733
larynx0 / 241450 
liver7 / 20774333
lung7 / 33697420
lymph0 / 442700 
lymph node10 / 91610109
mammary gland5 / 15327132
mouth7 / 67052104
muscle4 / 10771537
nerve1 / 1576863
ovary3 / 10205129
pancreas3 / 21481213
parathyroid2 / 2053997
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta11 / 28082539
prostate6 / 18934531
salivary gland0 / 201550 
skin9 / 21057442
spleen1 / 5395218
stomach3 / 9661931
testis23 / 33044269
thymus1 / 8113112
thyroid4 / 4747384
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus13 / 23287855
vascular4 / 5178077
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 218244_at
Cell line Expression level Expression bar
721_B_lymphoblasts109.3
Adipocyte7.15
AdrenalCortex6.4
Adrenalgland5.65
Amygdala6.85
Appendix7.75
AtrioventricularNode8.95
BDCA4+_DentriticCells73.25
Bonemarrow7.15
BronchialEpithelialCells6.9
CD105+_Endothelial48.5
CD14+_Monocytes16.1
CD19+_BCells(neg._sel.)44.15
CD33+_Myeloid17.1
CD34+162.25
CD4+_Tcells83.55
CD56+_NKCells49.5
CD71+_EarlyErythroid12.9
CD8+_Tcells108.3
CardiacMyocytes9.45
Caudatenucleus5.8
Cerebellum5.2
CerebellumPeduncles7.15
CiliaryGanglion5.35
CingulateCortex6.9
Colorectaladenocarcinoma19.2
DorsalRootGanglion5.1
FetalThyroid7.75
Fetalbrain6.65
Fetalliver6
Fetallung6.1
GlobusPallidus4.8
Heart9.25
Hypothalamus10.15
Kidney5.25
Leukemia_chronicMyelogenousK-56239.15
Leukemia_promyelocytic-HL-6039.65
Leukemialymphoblastic(MOLT-4)44.3
Liver7.2
Lung6
Lymphnode38.95
Lymphoma_burkitts(Daudi)32.4
Lymphoma_burkitts(Raji)10.55
MedullaOblongata6.1
OccipitalLobe6.15
OlfactoryBulb6.25
Ovary5.05
Pancreas8.1
PancreaticIslet14.5
ParietalLobe7.6
Pituitary8
Placenta6.15
Pons6.2
PrefrontalCortex9.25
Prostate7.65
Salivarygland5.75
SkeletalMuscle9.25
Skin6.15
SmoothMuscle7.6
Spinalcord7.25
SubthalamicNucleus6.45
SuperiorCervicalGanglion8.1
TemporalLobe6.25
Testis5.45
TestisGermCell5.5
TestisIntersitial5.8
TestisLeydigCell6.9
TestisSeminiferousTubule5.6
Thalamus7
Thymus5.1
Thyroid14.35
Tongue6.85
Tonsil14.85
Trachea5.65
TrigeminalGanglion7.25
Uterus13.75
UterusCorpus6.7
WholeBlood14.45
Wholebrain5.3
colon5.35
pineal_day10.18
pineal_night10.32
retina6.775
small_intestine5.05
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P71591
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala9.53 ± 0.25
Basal Forebrain9.51 ± 0.25
Basal Part of Pons9.24 ± 0.27
Cerebellar Cortex9.22 ± 0.12
Cerebellar Nuclei9.43 ± 0.19
Claustrum9.68 ± 0.27
Epithalamus9.41 ± 0.32
Frontal Lobe9.28 ± 0.25
Globus Pallidus9.98 ± 0.16
Hypothalamus9.34 ± 0.22
Insula9.29 ± 0.19
Limbic Lobe9.43 ± 0.3
Mesencephalon9.5 ± 0.25
Myelencephalon9.41 ± 0.26
Occipital Lobe9.55 ± 0.26
Parietal Lobe9.4 ± 0.26
Pontine Tegmentum9.41 ± 0.26
Striatum9.76 ± 0.24
Subthalamus9.43 ± 0.22
Temporal Lobe9.31 ± 0.22
Thalamus9.41 ± 0.2
White Matter10.4 ± 0.29
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Nol8STRdStriatum dorsal region8.99
5.87
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00073599 13 866 878 LMDLQSHFGTDDR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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