AutismKB 2.0

Annotation Detail for TRMT12


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Basic Information Top
Gene Symbol:TRMT12 ( FLJ20772,TRM12,TYW2 )
Gene Full Name: tRNA methyltransferase 12 homolog (S. cerevisiae)
Band: 8q24.13
Quick LinksEntrez ID:55039; OMIM: 611244; Uniprot ID:TYW2_HUMAN; ENSEMBL ID: ENSG00000183665; HGNC ID: 26091
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst3 / 6231948
fetus17 / 56401230
neonate1 / 3109732
infant2 / 2362084
juvenile1 / 5555617
adult29 / 193912114
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor4 / 9417842
cervical tumor2 / 3436658
chondrosarcoma0 / 828230 
colorectal tumor3 / 11424626
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor4 / 26384515
glioma2 / 10688318
head and neck tumor1 / 1363027
kidney tumor4 / 6895958
leukemia1 / 9584210
liver tumor5 / 9635951
lung tumor1 / 1031279
lymphoma4 / 7175555
non-neoplasia0 / 972500 
normal75 / 336030722
ovarian tumor5 / 7668265
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS5 / 12568039
prostate cancer2 / 10268019
retinoblastoma0 / 463560 
skin tumor5 / 12494940
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor3 / 9025733
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites1 / 4001524
bladder0 / 297570 
blood3 / 12347824
bone0 / 716550 
bone marrow0 / 488010 
brain27 / 110098924
cervix2 / 4817141
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue7 / 21572232
esophagus0 / 202090 
eye3 / 21105414
heart0 / 896260 
intestine6 / 23447225
kidney12 / 21177756
larynx1 / 2414541
liver5 / 20774324
lung5 / 33697414
lymph0 / 442700 
lymph node1 / 9161010
mammary gland5 / 15327132
mouth0 / 670520 
muscle3 / 10771527
nerve0 / 157680 
ovary6 / 10205158
pancreas4 / 21481218
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta5 / 28082517
prostate5 / 18934526
salivary gland0 / 201550 
skin6 / 21057428
spleen2 / 5395237
stomach1 / 9661910
testis4 / 33044212
thymus1 / 8113112
thyroid0 / 474730 
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus8 / 23287834
vascular3 / 5178057
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 219299_at
Cell line Expression level Expression bar
721_B_lymphoblasts6.9
Adipocyte5.3
AdrenalCortex5.75
Adrenalgland4.1
Amygdala5.65
Appendix5.3
AtrioventricularNode4
BDCA4+_DentriticCells9.25
Bonemarrow5.2
BronchialEpithelialCells5.6
CD105+_Endothelial20.35
CD14+_Monocytes18.85
CD19+_BCells(neg._sel.)19.65
CD33+_Myeloid7.15
CD34+22.4
CD4+_Tcells6.8
CD56+_NKCells13.55
CD71+_EarlyErythroid5.05
CD8+_Tcells6.85
CardiacMyocytes6.95
Caudatenucleus4.8
Cerebellum4.3
CerebellumPeduncles5.55
CiliaryGanglion3.8
CingulateCortex5.45
Colorectaladenocarcinoma6.4
DorsalRootGanglion4.3
FetalThyroid5.2
Fetalbrain5.4
Fetalliver4.55
Fetallung4.4
GlobusPallidus3.85
Heart7.05
Hypothalamus5.8
Kidney4.2
Leukemia_chronicMyelogenousK-5624.85
Leukemia_promyelocytic-HL-604.75
Leukemialymphoblastic(MOLT-4)4.3
Liver6.9
Lung6
Lymphnode4.5
Lymphoma_burkitts(Daudi)6.45
Lymphoma_burkitts(Raji)7.5
MedullaOblongata4.85
OccipitalLobe4.85
OlfactoryBulb3.8
Ovary4.5
Pancreas4.25
PancreaticIslet5.7
ParietalLobe5.55
Pituitary6.25
Placenta5.3
Pons5.05
PrefrontalCortex6.65
Prostate6.15
Salivarygland4.6
SkeletalMuscle6.05
Skin4.25
SmoothMuscle6.05
Spinalcord5.7
SubthalamicNucleus4.9
SuperiorCervicalGanglion6.6
TemporalLobe4.8
Testis4.7
TestisGermCell4.45
TestisIntersitial4.6
TestisLeydigCell5.25
TestisSeminiferousTubule4.6
Thalamus5.45
Thymus4.25
Thyroid7.65
Tongue4.9
Tonsil5.2
Trachea4.15
TrigeminalGanglion6.35
Uterus4.6
UterusCorpus4.7
WholeBlood5.9
Wholebrain4.65
colon5.4
pineal_day10.1
pineal_night6.9
retina9.1
small_intestine5.85
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_12855_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.39 ± 0.52
Basal Forebrain5.16 ± 0.35
Basal Part of Pons5.34 ± 0.41
Cerebellar Cortex5.53 ± 0.27
Cerebellar Nuclei4.66 ± 0.45
Claustrum5.47 ± 0.59
Epithalamus5.81 ± 0.57
Frontal Lobe5.37 ± 0.46
Globus Pallidus4.8 ± 0.37
Hypothalamus5.26 ± 0.36
Insula5.36 ± 0.31
Limbic Lobe5.51 ± 0.35
Mesencephalon5.17 ± 0.48
Myelencephalon5.35 ± 0.42
Occipital Lobe5.17 ± 0.39
Parietal Lobe5.4 ± 0.47
Pontine Tegmentum5.4 ± 0.49
Striatum5.05 ± 0.45
Subthalamus5.45 ± 0.06
Temporal Lobe5.44 ± 0.35
Thalamus5.24 ± 0.44
White Matter5.12 ± 0.12
Mouse Brain ISH
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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