AutismKB 2.0

Annotation Detail for DET1


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:DET1 ( FLJ10103,MGC126156,MGC126157 )
Gene Full Name: de-etiolated homolog 1 (Arabidopsis)
Band: 15q26.1
Quick LinksEntrez ID:55070; OMIM: 608727; Uniprot ID:DET1_HUMAN; ENSEMBL ID: ENSG00000140543; HGNC ID: 25477
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst1 / 6231916
fetus10 / 56401217
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult26 / 193912113
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor3 / 26384511
glioma0 / 1068830 
head and neck tumor2 / 13630214
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor4 / 10312738
lymphoma1 / 7175513
non-neoplasia1 / 9725010
normal60 / 336030717
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS5 / 12568039
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood1 / 1234788
bone0 / 716550 
bone marrow0 / 488010 
brain14 / 110098912
cervix0 / 481710 
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue5 / 21572223
esophagus0 / 202090 
eye2 / 2110549
heart1 / 8962611
intestine2 / 2344728
kidney3 / 21177714
larynx2 / 2414582
liver0 / 2077430 
lung8 / 33697423
lymph1 / 4427022
lymph node3 / 9161032
mammary gland1 / 1532716
mouth0 / 670520 
muscle1 / 1077159
nerve0 / 157680 
ovary0 / 1020510 
pancreas4 / 21481218
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta4 / 28082514
prostate7 / 18934536
salivary gland0 / 201550 
skin1 / 2105744
spleen2 / 5395237
stomach0 / 966190 
testis4 / 33044212
thymus1 / 8113112
thyroid0 / 474730 
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus3 / 23287812
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 219641_at
Cell line Expression level Expression bar
721_B_lymphoblasts4.05
Adipocyte3.15
AdrenalCortex3.3
Adrenalgland2.65
Amygdala3.4
Appendix3.2
AtrioventricularNode2.4
BDCA4+_DentriticCells3.6
Bonemarrow3.15
BronchialEpithelialCells3.15
CD105+_Endothelial3.25
CD14+_Monocytes3.4
CD19+_BCells(neg._sel.)3.45
CD33+_Myeloid4.15
CD34+4.1
CD4+_Tcells3.55
CD56+_NKCells3.85
CD71+_EarlyErythroid3
CD8+_Tcells3.15
CardiacMyocytes4
Caudatenucleus2.85
Cerebellum2.6
CerebellumPeduncles3.6
CiliaryGanglion2.2
CingulateCortex3.25
Colorectaladenocarcinoma3.15
DorsalRootGanglion2.4
FetalThyroid3.1
Fetalbrain3.25
Fetalliver2.7
Fetallung2.7
GlobusPallidus2.3
Heart4
Hypothalamus3.45
Kidney2.55
Leukemia_chronicMyelogenousK-5622.85
Leukemia_promyelocytic-HL-602.8
Leukemialymphoblastic(MOLT-4)2.55
Liver4.15
Lung3.55
Lymphnode2.8
Lymphoma_burkitts(Daudi)4.05
Lymphoma_burkitts(Raji)4.4
MedullaOblongata2.95
OccipitalLobe2.9
OlfactoryBulb2.5
Ovary2.1
Pancreas2.55
PancreaticIslet3.4
ParietalLobe3.35
Pituitary3.7
Placenta3.35
Pons3
PrefrontalCortex4.1
Prostate3.8
Salivarygland2.5
SkeletalMuscle3.55
Skin2.4
SmoothMuscle3.6
Spinalcord3.4
SubthalamicNucleus2.85
SuperiorCervicalGanglion3.55
TemporalLobe2.9
Testis2.8
TestisGermCell2.7
TestisIntersitial2.65
TestisLeydigCell3.15
TestisSeminiferousTubule2.75
Thalamus3.2
Thymus2.6
Thyroid4.05
Tongue3.05
Tonsil3.15
Trachea2.7
TrigeminalGanglion3.15
Uterus3.1
UterusCorpus2.85
WholeBlood3.55
Wholebrain2.75
colon3.2
pineal_day4.04
pineal_night3.9
retina3.875
small_intestine3.1
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_9592_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.4 ± 0.73
Basal Forebrain3.24 ± 0.68
Basal Part of Pons3.64 ± 0.57
Cerebellar Cortex3.81 ± 0.45
Cerebellar Nuclei3.58 ± 0.51
Claustrum3.13 ± 0.68
Epithalamus3.64 ± 0.6
Frontal Lobe3.59 ± 0.48
Globus Pallidus3.22 ± 0.65
Hypothalamus3.27 ± 0.42
Insula3.73 ± 0.24
Limbic Lobe3.41 ± 0.61
Mesencephalon3.5 ± 0.6
Myelencephalon3.53 ± 0.59
Occipital Lobe3.39 ± 0.59
Parietal Lobe3.4 ± 0.67
Pontine Tegmentum3.45 ± 0.54
Striatum3.14 ± 0.68
Subthalamus3.78 ± 0.75
Temporal Lobe3.54 ± 0.57
Thalamus3.41 ± 0.54
White Matter4.03 ± 0.28
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Det1CBCerebellum0
0
Det1CTXCerebral cortex0
0
Det1HIPHippocampal region0
0
Det1HPFHippocampal formation0
0
Det1HYHypothalamus0
0
Det1LSXLateral septal complex0
0
Det1MBMidbrain0
0
Det1MYMedulla0
0
Det1OLFOlfactory bulb0
0
Det1PPons0
0
Det1PALPallidum0
0
Det1RHPRetrohippocampal region0
0
Det1sAMYStriatum-like amygdalar nuclei0
0
Det1STRStriatum0
0
Det1STRdStriatum dorsal region0
0
Det1STRvStriatum ventral region0
0
Det1THThalamus0
0
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved