AutismKB 2.0

Annotation Detail for RNF31


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Basic Information Top
Gene Symbol:RNF31 ( FLJ10111,FLJ23501,HOIP,MGC19975,ZIBRA )
Gene Full Name: ring finger protein 31
Band: 14q12
Quick LinksEntrez ID:55072; OMIM: 612487; Uniprot ID:RNF31_HUMAN; ENSEMBL ID: ENSG00000092098; HGNC ID: 16031
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body4 / 7076156
blastocyst2 / 6231932
fetus24 / 56401242
neonate1 / 3109732
infant0 / 236200 
juvenile0 / 555560 
adult148 / 193912176
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor16 / 94178169
cervical tumor1 / 3436629
chondrosarcoma2 / 8282324
colorectal tumor3 / 11424626
esophageal tumor0 / 172900 
gastrointestinal tumor5 / 11936941
germ cell tumor10 / 26384537
glioma11 / 106883102
head and neck tumor12 / 13630288
kidney tumor1 / 6895914
leukemia7 / 9584273
liver tumor4 / 9635941
lung tumor17 / 103127164
lymphoma3 / 7175541
non-neoplasia7 / 9725071
normal162 / 336030748
ovarian tumor28 / 76682365
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS6 / 12568047
prostate cancer1 / 1026809
retinoblastoma1 / 4635621
skin tumor14 / 124949112
soft tissue/muscle tissue tumor7 / 12519155
uterine tumor3 / 9025733
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland1 / 3319730
ascites3 / 4001574
bladder0 / 297570 
blood7 / 12347856
bone1 / 7165513
bone marrow18 / 48801368
brain65 / 110098959
cervix5 / 48171103
connective tissue6 / 14925540
ear0 / 162120 
embryonic tissue11 / 21572250
esophagus0 / 202090 
eye10 / 21105447
heart0 / 896260 
intestine9 / 23447238
kidney3 / 21177714
larynx0 / 241450 
liver6 / 20774328
lung35 / 336974103
lymph0 / 442700 
lymph node4 / 9161043
mammary gland19 / 153271123
mouth10 / 67052149
muscle9 / 10771583
nerve3 / 15768190
ovary29 / 102051284
pancreas9 / 21481241
parathyroid0 / 205390 
pharynx2 / 4132848
pituitary gland0 / 165850 
placenta15 / 28082553
prostate2 / 18934510
salivary gland0 / 201550 
skin20 / 21057494
spleen1 / 5395218
stomach2 / 9661920
testis24 / 33044272
thymus20 / 81131246
thyroid2 / 4747342
tonsil0 / 169990 
trachea4 / 5241376
umbilical cord2 / 13680146
uterus15 / 23287864
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 220788_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts28.05
Adipocyte15.85
AdrenalCortex19.6
Adrenalgland19.3
Amygdala16.4
Appendix18.1
AtrioventricularNode14.8
BDCA4+_DentriticCells30.2
Bonemarrow16.85
BronchialEpithelialCells16
CD105+_Endothelial15.65
CD14+_Monocytes20.75
CD19+_BCells(neg._sel.)15.55
CD33+_Myeloid21
CD34+20.6
CD4+_Tcells25.35
CD56+_NKCells32.35
CD71+_EarlyErythroid13.9
CD8+_Tcells28
CardiacMyocytes22.35
Caudatenucleus15.05
Cerebellum13.95
CerebellumPeduncles19.9
CiliaryGanglion13.25
CingulateCortex17
Colorectaladenocarcinoma18.95
DorsalRootGanglion13.45
FetalThyroid18.15
Fetalbrain16.65
Fetalliver14.1
Fetallung12.3
GlobusPallidus12.8
Heart37.15
Hypothalamus16.55
Kidney17.35
Leukemia_chronicMyelogenousK-56214.3
Leukemia_promyelocytic-HL-6014.55
Leukemialymphoblastic(MOLT-4)13.65
Liver25.9
Lung27.65
Lymphnode15.1
Lymphoma_burkitts(Daudi)22.35
Lymphoma_burkitts(Raji)27.65
MedullaOblongata14.9
OccipitalLobe15.2
OlfactoryBulb12.25
Ovary11.6
Pancreas14.95
PancreaticIslet17.95
ParietalLobe18.45
Pituitary21.1
Placenta17
Pons18.25
PrefrontalCortex19.05
Prostate19.45
Salivarygland13.95
SkeletalMuscle36.15
Skin13.4
SmoothMuscle19.5
Spinalcord18.25
SubthalamicNucleus15.7
SuperiorCervicalGanglion22.5
TemporalLobe15.2
Testis15.35
TestisGermCell13.3
TestisIntersitial15.95
TestisLeydigCell16.85
TestisSeminiferousTubule13.9
Thalamus13.55
Thymus27.4
Thyroid20.6
Tongue20.25
Tonsil17.75
Trachea14.2
TrigeminalGanglion18.35
Uterus12.05
UterusCorpus16.3
WholeBlood33
Wholebrain16.8
colon15.5
pineal_day18.3
pineal_night18.28
retina20.2
small_intestine14.6
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_15137_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5 ± 0.65
Basal Forebrain5.19 ± 0.63
Basal Part of Pons5.43 ± 0.49
Cerebellar Cortex5.61 ± 0.51
Cerebellar Nuclei4.72 ± 0.63
Claustrum4.45 ± 0.88
Epithalamus5.14 ± 0.77
Frontal Lobe5.38 ± 0.56
Globus Pallidus4.71 ± 0.31
Hypothalamus5.12 ± 0.65
Insula5.58 ± 0.3
Limbic Lobe5.16 ± 0.66
Mesencephalon5.07 ± 0.53
Myelencephalon5.25 ± 0.58
Occipital Lobe4.99 ± 0.49
Parietal Lobe5.13 ± 0.53
Pontine Tegmentum5.07 ± 0.59
Striatum4.9 ± 0.51
Subthalamus4.95 ± 0.22
Temporal Lobe5.43 ± 0.47
Thalamus5.31 ± 0.46
White Matter4.76 ± 0.64
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Rnf31CBCerebellum32.67
33.59
Rnf31CTXCerebral cortex24
15.42
Rnf31HIPHippocampal region29.28
33.62
Rnf31HPFHippocampal formation28.04
26.2
Rnf31HYHypothalamus16.2
11.23
Rnf31LSXLateral septal complex8.2
5
Rnf31MBMidbrain19.32
14.89
Rnf31MYMedulla30.72
27.93
Rnf31OLFOlfactory bulb41.09
29.31
Rnf31PPons27.64
24.05
Rnf31PALPallidum10.48
7.68
Rnf31RHPRetrohippocampal region25.69
17.53
Rnf31sAMYStriatum-like amygdalar nuclei17.03
10.95
Rnf31STRStriatum9.2
6.15
Rnf31STRdStriatum dorsal region6.75
4.7
Rnf31STRvStriatum ventral region12.56
7.75
Rnf31THThalamus28.12
20.71
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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