AutismKB 2.0

Annotation Detail for SOBP


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Basic Information Top
Gene Symbol:SOBP ( FLJ10159,JXC1 )
Gene Full Name: sine oculis binding protein homolog (Drosophila)
Band: 6q21
Quick LinksEntrez ID:55084; OMIM: NA; Uniprot ID:SOBP_HUMAN; ENSEMBL ID: ENSG00000112320; HGNC ID: 29256
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus27 / 56401247
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult37 / 193912119
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor3 / 11424626
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor12 / 26384545
glioma14 / 106883130
head and neck tumor3 / 13630222
kidney tumor2 / 6895929
leukemia0 / 958420 
liver tumor1 / 9635910
lung tumor0 / 1031270 
lymphoma2 / 7175527
non-neoplasia1 / 9725010
normal86 / 336030725
ovarian tumor2 / 7668226
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer3 / 10268029
retinoblastoma1 / 4635621
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor7 / 12519155
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone1 / 7165513
bone marrow0 / 488010 
brain26 / 110098923
cervix0 / 481710 
connective tissue8 / 14925553
ear2 / 16212123
embryonic tissue1 / 2157224
esophagus0 / 202090 
eye10 / 21105447
heart3 / 8962633
intestine7 / 23447229
kidney4 / 21177718
larynx0 / 241450 
liver1 / 2077434
lung27 / 33697480
lymph0 / 442700 
lymph node1 / 9161010
mammary gland0 / 1532710 
mouth0 / 670520 
muscle1 / 1077159
nerve0 / 157680 
ovary3 / 10205129
pancreas9 / 21481241
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate10 / 18934552
salivary gland2 / 2015599
skin0 / 2105740 
spleen1 / 5395218
stomach0 / 966190 
testis2 / 3304426
thymus1 / 8113112
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus4 / 23287817
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 218974_at
Cell line Expression level Expression bar
721_B_lymphoblasts8.45
Adipocyte29
AdrenalCortex24
Adrenalgland15.55
Amygdala413.6
Appendix12.35
AtrioventricularNode4.4
BDCA4+_DentriticCells5
Bonemarrow4.7
BronchialEpithelialCells4.25
CD105+_Endothelial9.55
CD14+_Monocytes5
CD19+_BCells(neg._sel.)40.65
CD33+_Myeloid5.95
CD34+5.65
CD4+_Tcells5.65
CD56+_NKCells5.45
CD71+_EarlyErythroid4.45
CD8+_Tcells4.4
CardiacMyocytes6.7
Caudatenucleus68.85
Cerebellum132.05
CerebellumPeduncles213.95
CiliaryGanglion4.2
CingulateCortex271.85
Colorectaladenocarcinoma4.55
DorsalRootGanglion3.65
FetalThyroid16
Fetalbrain950.25
Fetalliver9.4
Fetallung6.65
GlobusPallidus107.45
Heart9.55
Hypothalamus177.85
Kidney3.85
Leukemia_chronicMyelogenousK-5624.25
Leukemia_promyelocytic-HL-603.9
Leukemialymphoblastic(MOLT-4)3.7
Liver5.7
Lung8.5
Lymphnode3.75
Lymphoma_burkitts(Daudi)29
Lymphoma_burkitts(Raji)5.5
MedullaOblongata160.75
OccipitalLobe296.55
OlfactoryBulb12.5
Ovary4.4
Pancreas3.95
PancreaticIslet20.75
ParietalLobe216.85
Pituitary62.7
Placenta5.5
Pons98.45
PrefrontalCortex394.7
Prostate31.55
Salivarygland10.1
SkeletalMuscle8.3
Skin3.85
SmoothMuscle5.9
Spinalcord45.45
SubthalamicNucleus158.65
SuperiorCervicalGanglion6.3
TemporalLobe143.4
Testis19.8
TestisGermCell33.8
TestisIntersitial47.3
TestisLeydigCell32.9
TestisSeminiferousTubule27
Thalamus118.15
Thymus7.25
Thyroid15.5
Tongue5.3
Tonsil4.65
Trachea7.5
TrigeminalGanglion5.7
Uterus26.95
UterusCorpus4.75
WholeBlood4.85
Wholebrain358.6
colon28.5
pineal_day85.2
pineal_night83.54
retina135.825
small_intestine16.85
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P551530
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.41 ± 0.62
Basal Forebrain7.24 ± 0.13
Basal Part of Pons7.31 ± 0.4
Cerebellar Cortex6.69 ± 0.29
Cerebellar Nuclei7.29 ± 0.39
Claustrum7.75 ± 0.56
Epithalamus6.51 ± 0.37
Frontal Lobe7.07 ± 0.45
Globus Pallidus7.6 ± 0.25
Hypothalamus7.06 ± 0.53
Insula6.96 ± 0.43
Limbic Lobe7.14 ± 0.46
Mesencephalon7.21 ± 0.44
Myelencephalon7.15 ± 0.52
Occipital Lobe6.98 ± 0.47
Parietal Lobe7.09 ± 0.48
Pontine Tegmentum6.92 ± 0.41
Striatum7.38 ± 0.49
Subthalamus7.03 ± 0.26
Temporal Lobe6.99 ± 0.53
Thalamus7.1 ± 0.42
White Matter7.43 ± 0.18
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
5330439J01RikCBCerebellum100
100
5330439J01RikCTXCerebral cortex100
100
5330439J01RikHIPHippocampal region100
100
5330439J01RikHPFHippocampal formation100
100
5330439J01RikHYHypothalamus64.17
56.26
5330439J01RikLSXLateral septal complex100
100
5330439J01RikMBMidbrain66.6
64.42
5330439J01RikMYMedulla58.42
68.79
5330439J01RikOLFOlfactory bulb100
100
5330439J01RikPPons60.96
61.65
5330439J01RikPALPallidum78.43
75.75
5330439J01RikRHPRetrohippocampal region100
100
5330439J01RiksAMYStriatum-like amygdalar nuclei73.93
63.18
5330439J01RikSTRStriatum56.37
46.85
5330439J01RikSTRdStriatum dorsal region37.26
31.36
5330439J01RikSTRvStriatum ventral region76.8
58.87
5330439J01RikTHThalamus59.75
53.4
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018