AutismKB 2.0

Annotation Detail for TMEM51


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Basic Information Top
Gene Symbol:TMEM51 ( C1orf72,FLJ10199 )
Gene Full Name: transmembrane protein 51
Band: 1p36.21
Quick LinksEntrez ID:55092; OMIM: NA; Uniprot ID:TMM51_HUMAN; ENSEMBL ID: ENSG00000171729; HGNC ID: 25488
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body3 / 7076142
blastocyst2 / 6231932
fetus16 / 56401228
neonate1 / 3109732
infant0 / 236200 
juvenile0 / 555560 
adult41 / 193912121
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor8 / 9417884
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor2 / 11424617
esophageal tumor2 / 17290115
gastrointestinal tumor9 / 11936975
germ cell tumor0 / 2638450 
glioma3 / 10688328
head and neck tumor6 / 13630244
kidney tumor9 / 68959130
leukemia3 / 9584231
liver tumor1 / 9635910
lung tumor2 / 10312719
lymphoma0 / 717550 
non-neoplasia1 / 9725010
normal83 / 336030724
ovarian tumor0 / 766820 
pancreatic tumor6 / 10461657
primitive neuroectodermal tumor of the CNS5 / 12568039
prostate cancer1 / 1026809
retinoblastoma6 / 46356129
skin tumor13 / 124949104
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor5 / 9025755
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites1 / 4001524
bladder1 / 2975733
blood3 / 12347824
bone1 / 7165513
bone marrow0 / 488010 
brain13 / 110098911
cervix0 / 481710 
connective tissue3 / 14925520
ear1 / 1621261
embryonic tissue8 / 21572237
esophagus2 / 2020998
eye8 / 21105437
heart0 / 896260 
intestine6 / 23447225
kidney21 / 21177799
larynx3 / 24145124
liver1 / 2077434
lung19 / 33697456
lymph0 / 442700 
lymph node2 / 9161021
mammary gland8 / 15327152
mouth0 / 670520 
muscle0 / 1077150 
nerve1 / 1576863
ovary1 / 1020519
pancreas22 / 214812102
parathyroid3 / 20539146
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta2 / 2808257
prostate3 / 18934515
salivary gland0 / 201550 
skin15 / 21057471
spleen0 / 539520 
stomach10 / 96619103
testis2 / 3304426
thymus1 / 8113112
thyroid3 / 4747363
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord1 / 1368073
uterus7 / 23287830
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 218815_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts6.55
Adipocyte5.35
AdrenalCortex6.1
Adrenalgland4.65
Amygdala5.5
Appendix5.8
AtrioventricularNode5.7
BDCA4+_DentriticCells5.5
Bonemarrow5.2
BronchialEpithelialCells6.15
CD105+_Endothelial5.45
CD14+_Monocytes5.75
CD19+_BCells(neg._sel.)5.4
CD33+_Myeloid7
CD34+6.9
CD4+_Tcells5.8
CD56+_NKCells5.85
CD71+_EarlyErythroid5
CD8+_Tcells4.9
CardiacMyocytes6.55
Caudatenucleus4.8
Cerebellum5.2
CerebellumPeduncles8.25
CiliaryGanglion4.5
CingulateCortex5.45
Colorectaladenocarcinoma5.4
DorsalRootGanglion6.25
FetalThyroid5.2
Fetalbrain5.45
Fetalliver4.6
Fetallung4.6
GlobusPallidus3.9
Heart6.65
Hypothalamus5.95
Kidney5.25
Leukemia_chronicMyelogenousK-5624.9
Leukemia_promyelocytic-HL-604.75
Leukemialymphoblastic(MOLT-4)4.35
Liver6.95
Lung6
Lymphnode4.7
Lymphoma_burkitts(Daudi)6.85
Lymphoma_burkitts(Raji)7.35
MedullaOblongata4.85
OccipitalLobe4.85
OlfactoryBulb4.6
Ovary3.8
Pancreas6.35
PancreaticIslet7.55
ParietalLobe5.8
Pituitary6.35
Placenta5.65
Pons5.25
PrefrontalCortex6.75
Prostate6.4
Salivarygland4.3
SkeletalMuscle5.95
Skin4.25
SmoothMuscle6.2
Spinalcord5.75
SubthalamicNucleus4.85
SuperiorCervicalGanglion8.25
TemporalLobe4.9
Testis4.55
TestisGermCell4.35
TestisIntersitial4.5
TestisLeydigCell5.3
TestisSeminiferousTubule4.6
Thalamus5.45
Thymus4.3
Thyroid6.8
Tongue5.6
Tonsil5.3
Trachea4.55
TrigeminalGanglion6.15
Uterus4.35
UterusCorpus4.75
WholeBlood5.85
Wholebrain4.7
colon5.45
pineal_day6.66
pineal_night6.58
retina6.6
small_intestine5.3
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P12044
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.93 ± 0.26
Basal Forebrain7.7 ± 0.2
Basal Part of Pons7.94 ± 0.33
Cerebellar Cortex8.31 ± 0.36
Cerebellar Nuclei7.93 ± 0.24
Claustrum7.48 ± 0.48
Epithalamus7.74 ± 0.59
Frontal Lobe7.6 ± 0.43
Globus Pallidus7.48 ± 0.38
Hypothalamus7.26 ± 0.52
Insula7.67 ± 0.37
Limbic Lobe7.62 ± 0.56
Mesencephalon7.69 ± 0.45
Myelencephalon7.72 ± 0.41
Occipital Lobe7.84 ± 0.5
Parietal Lobe7.67 ± 0.4
Pontine Tegmentum7.74 ± 0.49
Striatum8.04 ± 0.66
Subthalamus7.62 ± 0.18
Temporal Lobe7.64 ± 0.36
Thalamus7.81 ± 0.56
White Matter6.94 ± 0.41
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Tmem51CBCerebellum3.41
4.77
Tmem51CTXCerebral cortex0.92
1.04
Tmem51HIPHippocampal region0.09
0.13
Tmem51HPFHippocampal formation0.3
0.36
Tmem51HYHypothalamus0.15
0.15
Tmem51LSXLateral septal complex0.09
0.12
Tmem51MBMidbrain0.19
0.36
Tmem51MYMedulla0.34
0.65
Tmem51OLFOlfactory bulb2.54
3.7
Tmem51PPons0.32
0.77
Tmem51PALPallidum0.14
0.14
Tmem51RHPRetrohippocampal region0.71
0.76
Tmem51sAMYStriatum-like amygdalar nuclei0
0
Tmem51STRStriatum0.14
0.15
Tmem51STRdStriatum dorsal region0.06
0.11
Tmem51STRvStriatum ventral region0.55
0.36
Tmem51THThalamus0.07
0.26
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00518677 36 93 128 QGEDLAHVQHPTGAGPHAQEEDSQEEEEEDEEAASR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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