AutismKB 2.0

Annotation Detail for WDR70


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Basic Information Top
Gene Symbol:WDR70 ( FLJ10233 )
Gene Full Name: WD repeat domain 70
Band: 5p13.2
Quick LinksEntrez ID:55100; OMIM: NA; Uniprot ID:WDR70_HUMAN; ENSEMBL ID: ENSG00000082068; HGNC ID: 25495
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst4 / 6231964
fetus24 / 56401242
neonate5 / 31097160
infant1 / 2362042
juvenile4 / 5555671
adult39 / 193912120
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor3 / 9417831
cervical tumor6 / 34366174
chondrosarcoma5 / 8282360
colorectal tumor2 / 11424617
esophageal tumor3 / 17290173
gastrointestinal tumor4 / 11936933
germ cell tumor9 / 26384534
glioma2 / 10688318
head and neck tumor1 / 1363027
kidney tumor3 / 6895943
leukemia2 / 9584220
liver tumor13 / 96359134
lung tumor0 / 1031270 
lymphoma5 / 7175569
non-neoplasia0 / 972500 
normal94 / 336030727
ovarian tumor3 / 7668239
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS4 / 12568031
prostate cancer1 / 1026809
retinoblastoma3 / 4635664
skin tumor2 / 12494916
soft tissue/muscle tissue tumor8 / 12519163
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites2 / 4001549
bladder0 / 297570 
blood6 / 12347848
bone4 / 7165555
bone marrow1 / 4880120
brain35 / 110098931
cervix6 / 48171124
connective tissue9 / 14925560
ear0 / 162120 
embryonic tissue8 / 21572237
esophagus3 / 20209148
eye4 / 21105418
heart1 / 8962611
intestine7 / 23447229
kidney9 / 21177742
larynx1 / 2414541
liver13 / 20774362
lung4 / 33697411
lymph3 / 4427067
lymph node0 / 916100 
mammary gland5 / 15327132
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary2 / 10205119
pancreas1 / 2148124
parathyroid0 / 205390 
pharynx2 / 4132848
pituitary gland1 / 1658560
placenta6 / 28082521
prostate3 / 18934515
salivary gland0 / 201550 
skin2 / 2105749
spleen1 / 5395218
stomach3 / 9661931
testis7 / 33044221
thymus3 / 8113136
thyroid0 / 474730 
tonsil0 / 169990 
trachea2 / 5241338
umbilical cord4 / 13680292
uterus11 / 23287847
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 219193_at
Cell line Expression level Expression bar
721_B_lymphoblasts18.6
Adipocyte6.7
AdrenalCortex7.5
Adrenalgland6.35
Amygdala6.1
Appendix7.1
AtrioventricularNode5.7
BDCA4+_DentriticCells45.7
Bonemarrow7.15
BronchialEpithelialCells7.45
CD105+_Endothelial11.75
CD14+_Monocytes9.75
CD19+_BCells(neg._sel.)27.1
CD33+_Myeloid9.2
CD34+18.9
CD4+_Tcells10.3
CD56+_NKCells15.75
CD71+_EarlyErythroid6.55
CD8+_Tcells10.1
CardiacMyocytes8.65
Caudatenucleus6.6
Cerebellum5.4
CerebellumPeduncles7.45
CiliaryGanglion4.8
CingulateCortex7
Colorectaladenocarcinoma7
DorsalRootGanglion5.6
FetalThyroid6.45
Fetalbrain6.8
Fetalliver5.75
Fetallung6.15
GlobusPallidus5
Heart8.05
Hypothalamus7.3
Kidney5.4
Leukemia_chronicMyelogenousK-5627.3
Leukemia_promyelocytic-HL-606.15
Leukemialymphoblastic(MOLT-4)7
Liver8.9
Lung6.9
Lymphnode5.8
Lymphoma_burkitts(Daudi)8.6
Lymphoma_burkitts(Raji)9.25
MedullaOblongata6.25
OccipitalLobe5.6
OlfactoryBulb5.3
Ovary4.45
Pancreas5.4
PancreaticIslet7
ParietalLobe7
Pituitary8.35
Placenta6.85
Pons6.35
PrefrontalCortex8.15
Prostate7.35
Salivarygland5.45
SkeletalMuscle13.55
Skin5.4
SmoothMuscle7.85
Spinalcord7.1
SubthalamicNucleus6.05
SuperiorCervicalGanglion8.5
TemporalLobe6.2
Testis9.75
TestisGermCell6.65
TestisIntersitial6.65
TestisLeydigCell11
TestisSeminiferousTubule9.3
Thalamus6.65
Thymus5.4
Thyroid8
Tongue6.95
Tonsil6.6
Trachea5.55
TrigeminalGanglion9.2
Uterus5.45
UterusCorpus9.85
WholeBlood7.05
Wholebrain4.55
colon7.05
pineal_day8.16
pineal_night7.8
retina7.975
small_intestine6.5
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_82_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.96 ± 0.33
Basal Forebrain6.96 ± 0.26
Basal Part of Pons7.31 ± 0.22
Cerebellar Cortex7.29 ± 0.15
Cerebellar Nuclei7.14 ± 0.23
Claustrum7.06 ± 0.39
Epithalamus7.24 ± 0.17
Frontal Lobe7.09 ± 0.22
Globus Pallidus6.98 ± 0.17
Hypothalamus7.15 ± 0.23
Insula7.03 ± 0.22
Limbic Lobe7.03 ± 0.22
Mesencephalon7.05 ± 0.22
Myelencephalon7.07 ± 0.26
Occipital Lobe7.22 ± 0.17
Parietal Lobe7.15 ± 0.27
Pontine Tegmentum7.07 ± 0.23
Striatum6.85 ± 0.27
Subthalamus7.05 ± 0.23
Temporal Lobe7.13 ± 0.22
Thalamus7.05 ± 0.3
White Matter7.49 ± 0.04
Mouse Brain ISH
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00514107 10 170 179 IPDSHEITLK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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