AutismKB 2.0

Annotation Detail for TMEM39B


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Basic Information Top
Gene Symbol:TMEM39B ( FLJ10315 )
Gene Full Name: transmembrane protein 39B
Band: 1p35.2
Quick LinksEntrez ID:55116; OMIM: NA; Uniprot ID:TM39B_HUMAN; ENSEMBL ID: ENSG00000121775; HGNC ID: 25510
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst2 / 6231932
fetus28 / 56401249
neonate3 / 3109796
infant5 / 23620211
juvenile3 / 5555653
adult73 / 193912137
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor2 / 12794156
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor1 / 3436629
chondrosarcoma7 / 8282384
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor5 / 11936941
germ cell tumor9 / 26384534
glioma7 / 10688365
head and neck tumor6 / 13630244
kidney tumor0 / 689590 
leukemia5 / 9584252
liver tumor2 / 9635920
lung tumor2 / 10312719
lymphoma5 / 7175569
non-neoplasia2 / 9725020
normal110 / 336030732
ovarian tumor8 / 76682104
pancreatic tumor5 / 10461647
primitive neuroectodermal tumor of the CNS8 / 12568063
prostate cancer0 / 1026800 
retinoblastoma2 / 4635643
skin tumor10 / 12494980
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland2 / 3319760
ascites5 / 40015124
bladder0 / 297570 
blood5 / 12347840
bone8 / 71655111
bone marrow1 / 4880120
brain34 / 110098930
cervix4 / 4817183
connective tissue5 / 14925533
ear0 / 162120 
embryonic tissue7 / 21572232
esophagus0 / 202090 
eye6 / 21105428
heart0 / 896260 
intestine5 / 23447221
kidney5 / 21177723
larynx0 / 241450 
liver5 / 20774324
lung12 / 33697435
lymph0 / 442700 
lymph node2 / 9161021
mammary gland3 / 15327119
mouth4 / 6705259
muscle2 / 10771518
nerve0 / 157680 
ovary10 / 10205197
pancreas8 / 21481237
parathyroid0 / 205390 
pharynx2 / 4132848
pituitary gland0 / 165850 
placenta19 / 28082567
prostate1 / 1893455
salivary gland0 / 201550 
skin10 / 21057447
spleen0 / 539520 
stomach0 / 966190 
testis14 / 33044242
thymus1 / 8113112
thyroid1 / 4747321
tonsil1 / 1699958
trachea0 / 524130 
umbilical cord3 / 13680219
uterus10 / 23287842
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 218770_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts12.4
Adipocyte6.15
AdrenalCortex5.65
Adrenalgland5.3
Amygdala6.4
Appendix6.5
AtrioventricularNode4.25
BDCA4+_DentriticCells35.8
Bonemarrow6.1
BronchialEpithelialCells5.95
CD105+_Endothelial5.9
CD14+_Monocytes25.25
CD19+_BCells(neg._sel.)21.55
CD33+_Myeloid18.8
CD34+12.45
CD4+_Tcells6.85
CD56+_NKCells8.15
CD71+_EarlyErythroid5.75
CD8+_Tcells5.8
CardiacMyocytes7.95
Caudatenucleus5.55
Cerebellum5.7
CerebellumPeduncles6.95
CiliaryGanglion4.25
CingulateCortex6.9
Colorectaladenocarcinoma10.4
DorsalRootGanglion4.3
FetalThyroid6
Fetalbrain6.25
Fetalliver6.3
Fetallung6.25
GlobusPallidus4.5
Heart7.3
Hypothalamus6.65
Kidney4.95
Leukemia_chronicMyelogenousK-5626.7
Leukemia_promyelocytic-HL-606.95
Leukemialymphoblastic(MOLT-4)14.95
Liver8.5
Lung12.4
Lymphnode5.4
Lymphoma_burkitts(Daudi)21.25
Lymphoma_burkitts(Raji)23
MedullaOblongata6.05
OccipitalLobe5.35
OlfactoryBulb4.4
Ovary4.05
Pancreas4.9
PancreaticIslet6.6
ParietalLobe6.6
Pituitary7.25
Placenta9.95
Pons5.9
PrefrontalCortex7.4
Prostate7.3
Salivarygland4.85
SkeletalMuscle7.65
Skin4.7
SmoothMuscle14
Spinalcord6.45
SubthalamicNucleus5.7
SuperiorCervicalGanglion6.9
TemporalLobe5.7
Testis16.8
TestisGermCell6.2
TestisIntersitial5.05
TestisLeydigCell6.1
TestisSeminiferousTubule5.35
Thalamus6.2
Thymus11.55
Thyroid8.5
Tongue6
Tonsil6.05
Trachea5
TrigeminalGanglion5.1
Uterus10.1
UterusCorpus5.45
WholeBlood9.65
Wholebrain5.9
colon5.6
pineal_day7.76
pineal_night9.08
retina6.3
small_intestine4.9
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_6583_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.14 ± 0.45
Basal Forebrain5.25 ± 0.19
Basal Part of Pons5.25 ± 0.43
Cerebellar Cortex5.23 ± 0.34
Cerebellar Nuclei5.19 ± 0.38
Claustrum5.02 ± 0.58
Epithalamus5.31 ± 0.38
Frontal Lobe5.37 ± 0.42
Globus Pallidus4.77 ± 0.36
Hypothalamus5.25 ± 0.32
Insula5.43 ± 0.42
Limbic Lobe5.3 ± 0.47
Mesencephalon5.17 ± 0.47
Myelencephalon5.27 ± 0.4
Occipital Lobe5.27 ± 0.33
Parietal Lobe5.32 ± 0.37
Pontine Tegmentum5.33 ± 0.45
Striatum5.19 ± 0.42
Subthalamus5.29 ± 0.28
Temporal Lobe5.44 ± 0.36
Thalamus5.23 ± 0.4
White Matter5.31 ± 0.42
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Tmem39bCBCerebellum3.45
2.96
Tmem39bCTXCerebral cortex14.31
8.18
Tmem39bHIPHippocampal region8.76
7.06
Tmem39bHPFHippocampal formation8.51
6.22
Tmem39bHYHypothalamus2.56
1.53
Tmem39bLSXLateral septal complex0
0
Tmem39bMBMidbrain2.42
1.73
Tmem39bMYMedulla4.75
4.25
Tmem39bOLFOlfactory bulb32.92
21.54
Tmem39bPPons5.66
5.05
Tmem39bPALPallidum2.92
2.12
Tmem39bRHPRetrohippocampal region8.28
5.18
Tmem39bsAMYStriatum-like amygdalar nuclei3.99
2.28
Tmem39bSTRStriatum3.58
2.43
Tmem39bSTRdStriatum dorsal region2.15
1.68
Tmem39bSTRvStriatum ventral region9.45
5.23
Tmem39bTHThalamus2.74
1.65
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00505176 26 15 40 NPLCEPGSSGGSSGSHTSSASVTSVR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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