AutismKB 2.0

Annotation Detail for PRPF38B


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Basic Information Top
Gene Symbol:PRPF38B ( FLJ10330,MGC163218,MGC41809,NET1,RP11-293A10.1 )
Gene Full Name: PRP38 pre-mRNA processing factor 38 (yeast) domain containing B
Band: 1p13.3
Quick LinksEntrez ID:55119; OMIM: NA; Uniprot ID:PR38B_HUMAN; ENSEMBL ID: ENSG00000134186; HGNC ID: 25512
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body11 / 70761155
blastocyst6 / 6231996
fetus33 / 56401258
neonate0 / 310970 
infant3 / 23620127
juvenile3 / 5555653
adult106 / 193912154
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor4 / 9417842
cervical tumor2 / 3436658
chondrosarcoma4 / 8282348
colorectal tumor13 / 114246113
esophageal tumor4 / 17290231
gastrointestinal tumor4 / 11936933
germ cell tumor13 / 26384549
glioma2 / 10688318
head and neck tumor7 / 13630251
kidney tumor2 / 6895929
leukemia11 / 95842114
liver tumor7 / 9635972
lung tumor0 / 1031270 
lymphoma3 / 7175541
non-neoplasia4 / 9725041
normal178 / 336030752
ovarian tumor6 / 7668278
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS5 / 12568039
prostate cancer4 / 10268038
retinoblastoma3 / 4635664
skin tumor6 / 12494948
soft tissue/muscle tissue tumor6 / 12519147
uterine tumor9 / 9025799
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland2 / 3319760
ascites1 / 4001524
bladder2 / 2975767
blood8 / 12347864
bone2 / 7165527
bone marrow4 / 4880181
brain34 / 110098930
cervix2 / 4817141
connective tissue7 / 14925546
ear0 / 162120 
embryonic tissue22 / 215722101
esophagus4 / 20209197
eye8 / 21105437
heart2 / 8962622
intestine17 / 23447272
kidney7 / 21177733
larynx2 / 2414582
liver17 / 20774381
lung13 / 33697438
lymph0 / 442700 
lymph node10 / 91610109
mammary gland12 / 15327178
mouth1 / 6705214
muscle12 / 107715111
nerve1 / 1576863
ovary6 / 10205158
pancreas7 / 21481232
parathyroid0 / 205390 
pharynx2 / 4132848
pituitary gland1 / 1658560
placenta19 / 28082567
prostate6 / 18934531
salivary gland1 / 2015549
skin7 / 21057433
spleen6 / 53952111
stomach3 / 9661931
testis12 / 33044236
thymus8 / 8113198
thyroid4 / 4747384
tonsil1 / 1699958
trachea3 / 5241357
umbilical cord1 / 1368073
uterus16 / 23287868
vascular2 / 5178038
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 218040_at
Cell line Expression level Expression bar
721_B_lymphoblasts36.85
Adipocyte10.8
AdrenalCortex13.25
Adrenalgland10.05
Amygdala15.2
Appendix15.7
AtrioventricularNode10.25
BDCA4+_DentriticCells34.8
Bonemarrow12.55
BronchialEpithelialCells10.25
CD105+_Endothelial18.9
CD14+_Monocytes11.5
CD19+_BCells(neg._sel.)29.4
CD33+_Myeloid21.7
CD34+41.35
CD4+_Tcells39.05
CD56+_NKCells30.5
CD71+_EarlyErythroid10.65
CD8+_Tcells49.1
CardiacMyocytes24.65
Caudatenucleus9.5
Cerebellum9.15
CerebellumPeduncles13.7
CiliaryGanglion9.05
CingulateCortex11.35
Colorectaladenocarcinoma16.15
DorsalRootGanglion9.6
FetalThyroid12.05
Fetalbrain10.7
Fetalliver10.15
Fetallung9.65
GlobusPallidus8.3
Heart17.05
Hypothalamus10.95
Kidney9.85
Leukemia_chronicMyelogenousK-56210.85
Leukemia_promyelocytic-HL-609.75
Leukemialymphoblastic(MOLT-4)18.4
Liver17.15
Lung11.9
Lymphnode15.8
Lymphoma_burkitts(Daudi)15.3
Lymphoma_burkitts(Raji)30.85
MedullaOblongata10.2
OccipitalLobe9.45
OlfactoryBulb8.3
Ovary8.45
Pancreas10.6
PancreaticIslet16.35
ParietalLobe12
Pituitary12.7
Placenta9.5
Pons10.4
PrefrontalCortex14.25
Prostate14.7
Salivarygland9.3
SkeletalMuscle16.5
Skin11.6
SmoothMuscle12.75
Spinalcord11.4
SubthalamicNucleus9.55
SuperiorCervicalGanglion17.15
TemporalLobe10.75
Testis9.2
TestisGermCell8.35
TestisIntersitial9.3
TestisLeydigCell11.65
TestisSeminiferousTubule8.8
Thalamus11.4
Thymus12.15
Thyroid20.6
Tongue17.35
Tonsil13.7
Trachea8.85
TrigeminalGanglion19.8
Uterus17.25
UterusCorpus13.15
WholeBlood15.15
Wholebrain8.35
colon10.85
pineal_day16.3
pineal_night16.14
retina12.9
small_intestine10.2
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P222844
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala8.77 ± 0.35
Basal Forebrain8.61 ± 0.2
Basal Part of Pons8.28 ± 0.24
Cerebellar Cortex8.79 ± 0.16
Cerebellar Nuclei8.57 ± 0.31
Claustrum8.87 ± 0.46
Epithalamus8.36 ± 0.29
Frontal Lobe8.23 ± 0.36
Globus Pallidus9.16 ± 0.25
Hypothalamus8.11 ± 0.19
Insula8.29 ± 0.26
Limbic Lobe8.66 ± 0.52
Mesencephalon8.56 ± 0.33
Myelencephalon8.46 ± 0.4
Occipital Lobe8.85 ± 0.39
Parietal Lobe8.45 ± 0.44
Pontine Tegmentum8.4 ± 0.41
Striatum8.63 ± 0.52
Subthalamus8.19 ± 0.25
Temporal Lobe8.38 ± 0.36
Thalamus8.4 ± 0.27
White Matter9.56 ± 0.47
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Prpf38bCBCerebellum100
100
Prpf38bCTXCerebral cortex100
100
Prpf38bHIPHippocampal region95.22
100
Prpf38bHPFHippocampal formation100
100
Prpf38bHYHypothalamus94.32
90.39
Prpf38bLSXLateral septal complex100
100
Prpf38bMBMidbrain88.67
95.1
Prpf38bMYMedulla88.14
100
Prpf38bOLFOlfactory bulb100
100
Prpf38bPPons82.59
100
Prpf38bPALPallidum95.27
100
Prpf38bRHPRetrohippocampal region100
100
Prpf38bsAMYStriatum-like amygdalar nuclei100
100
Prpf38bSTRStriatum100
100
Prpf38bSTRdStriatum dorsal region100
96.11
Prpf38bSTRvStriatum ventral region100
100
Prpf38bTHThalamus97.31
94.74
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00079190 19 55 73 TMNLNPMILTNILSSPYFK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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