AutismKB 2.0

Annotation Detail for AKIRIN2


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Basic Information Top
Gene Symbol:AKIRIN2 ( C6orf166,FBI1,FLJ10342,dJ486L4.2 )
Gene Full Name: akirin 2
Band: 6q15
Quick LinksEntrez ID:55122; OMIM: NA; Uniprot ID:AKIR2_HUMAN; ENSEMBL ID: ENSG00000135334; HGNC ID: 21407
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body10 / 70761141
blastocyst1 / 6231916
fetus39 / 56401269
neonate0 / 310970 
infant12 / 23620508
juvenile2 / 5555635
adult113 / 193912158
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor6 / 9417863
cervical tumor0 / 343660 
chondrosarcoma9 / 82823108
colorectal tumor5 / 11424643
esophageal tumor1 / 1729057
gastrointestinal tumor1 / 1193698
germ cell tumor18 / 26384568
glioma10 / 10688393
head and neck tumor1 / 1363027
kidney tumor2 / 6895929
leukemia9 / 9584293
liver tumor3 / 9635931
lung tumor11 / 103127106
lymphoma4 / 7175555
non-neoplasia1 / 9725010
normal220 / 336030765
ovarian tumor11 / 76682143
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS15 / 125680119
prostate cancer2 / 10268019
retinoblastoma1 / 4635621
skin tumor4 / 12494932
soft tissue/muscle tissue tumor9 / 12519171
uterine tumor5 / 9025755
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue2 / 13106152
adrenal gland1 / 3319730
ascites1 / 4001524
bladder0 / 297570 
blood5 / 12347840
bone4 / 7165555
bone marrow2 / 4880140
brain69 / 110098962
cervix0 / 481710 
connective tissue8 / 14925553
ear0 / 162120 
embryonic tissue13 / 21572260
esophagus1 / 2020949
eye14 / 21105466
heart4 / 8962644
intestine23 / 23447298
kidney13 / 21177761
larynx0 / 241450 
liver5 / 20774324
lung34 / 336974100
lymph2 / 4427045
lymph node19 / 91610207
mammary gland7 / 15327145
mouth0 / 670520 
muscle8 / 10771574
nerve0 / 157680 
ovary12 / 102051117
pancreas7 / 21481232
parathyroid2 / 2053997
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta23 / 28082581
prostate5 / 18934526
salivary gland1 / 2015549
skin13 / 21057461
spleen3 / 5395255
stomach2 / 9661920
testis26 / 33044278
thymus20 / 81131246
thyroid0 / 474730 
tonsil3 / 16999176
trachea4 / 5241376
umbilical cord0 / 136800 
uterus15 / 23287864
vascular1 / 5178019
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P428827
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala9.21 ± 0.4
Basal Forebrain8.78 ± 0.08
Basal Part of Pons9 ± 0.22
Cerebellar Cortex8.56 ± 0.17
Cerebellar Nuclei8.64 ± 0.29
Claustrum9.02 ± 0.44
Epithalamus8.56 ± 0.26
Frontal Lobe8.75 ± 0.29
Globus Pallidus8.67 ± 0.12
Hypothalamus8.65 ± 0.36
Insula8.86 ± 0.37
Limbic Lobe9.15 ± 0.35
Mesencephalon8.79 ± 0.28
Myelencephalon8.84 ± 0.27
Occipital Lobe9.06 ± 0.32
Parietal Lobe8.78 ± 0.35
Pontine Tegmentum8.74 ± 0.21
Striatum9.36 ± 0.25
Subthalamus8.46 ± 0.16
Temporal Lobe8.84 ± 0.29
Thalamus8.76 ± 0.25
White Matter8.53 ± 0.48
Mouse Brain ISH
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018