AutismKB 2.0

Annotation Detail for TRIM68


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Basic Information Top
Gene Symbol:TRIM68 ( FLJ10369,GC109,MGC126176,RNF137,SS-56,SS56 )
Gene Full Name: tripartite motif-containing 68
Band: 11p15.4
Quick LinksEntrez ID:55128; OMIM: 613184; Uniprot ID:TRI68_HUMAN; ENSEMBL ID: ENSG00000167333; HGNC ID: 21161
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst1 / 6231916
fetus6 / 56401210
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult35 / 193912118
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor2 / 11424617
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor10 / 26384537
glioma2 / 10688318
head and neck tumor0 / 1363020 
kidney tumor2 / 6895929
leukemia3 / 9584231
liver tumor0 / 963590 
lung tumor1 / 1031279
lymphoma0 / 717550 
non-neoplasia3 / 9725030
normal53 / 336030715
ovarian tumor3 / 7668239
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer5 / 10268048
retinoblastoma0 / 463560 
skin tumor1 / 1249498
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder1 / 2975733
blood3 / 12347824
bone0 / 716550 
bone marrow0 / 488010 
brain22 / 110098919
cervix0 / 481710 
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue3 / 21572213
esophagus0 / 202090 
eye2 / 2110549
heart5 / 8962655
intestine3 / 23447212
kidney5 / 21177723
larynx0 / 241450 
liver0 / 2077430 
lung5 / 33697414
lymph0 / 442700 
lymph node0 / 916100 
mammary gland2 / 15327113
mouth1 / 6705214
muscle0 / 1077150 
nerve0 / 157680 
ovary3 / 10205129
pancreas2 / 2148129
parathyroid1 / 2053948
pharynx0 / 413280 
pituitary gland1 / 1658560
placenta3 / 28082510
prostate11 / 18934558
salivary gland0 / 201550 
skin2 / 2105749
spleen1 / 5395218
stomach0 / 966190 
testis15 / 33044245
thymus2 / 8113124
thyroid0 / 474730 
tonsil0 / 169990 
trachea6 / 52413114
umbilical cord0 / 136800 
uterus2 / 2328788
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 219405_at
Cell line Expression level Expression bar
721_B_lymphoblasts10.5
Adipocyte5.75
AdrenalCortex6
Adrenalgland5.1
Amygdala6.25
Appendix6.1
AtrioventricularNode5.5
BDCA4+_DentriticCells11.4
Bonemarrow5.85
BronchialEpithelialCells5.8
CD105+_Endothelial7.75
CD14+_Monocytes6
CD19+_BCells(neg._sel.)15.15
CD33+_Myeloid8.5
CD34+13.9
CD4+_Tcells9.9
CD56+_NKCells55.9
CD71+_EarlyErythroid5.6
CD8+_Tcells15.2
CardiacMyocytes7.55
Caudatenucleus5.25
Cerebellum4.8
CerebellumPeduncles6.6
CiliaryGanglion4.3
CingulateCortex6.05
Colorectaladenocarcinoma5.65
DorsalRootGanglion4.7
FetalThyroid6.7
Fetalbrain5.35
Fetalliver5.1
Fetallung4.8
GlobusPallidus4.35
Heart7.75
Hypothalamus6.55
Kidney4.9
Leukemia_chronicMyelogenousK-5625.2
Leukemia_promyelocytic-HL-605.05
Leukemialymphoblastic(MOLT-4)4.75
Liver7.95
Lung7.9
Lymphnode4.85
Lymphoma_burkitts(Daudi)7.5
Lymphoma_burkitts(Raji)8.05
MedullaOblongata5.4
OccipitalLobe5.25
OlfactoryBulb4.65
Ovary3.95
Pancreas4.4
PancreaticIslet6.15
ParietalLobe6.2
Pituitary6.9
Placenta8.6
Pons5.6
PrefrontalCortex7.95
Prostate17.45
Salivarygland4.75
SkeletalMuscle6.85
Skin4.75
SmoothMuscle6.55
Spinalcord6
SubthalamicNucleus5.4
SuperiorCervicalGanglion6.85
TemporalLobe5.7
Testis6
TestisGermCell5.1
TestisIntersitial7.8
TestisLeydigCell5.9
TestisSeminiferousTubule5.1
Thalamus5.75
Thymus6.2
Thyroid7.5
Tongue5.75
Tonsil5.5
Trachea4.8
TrigeminalGanglion6.65
Uterus4.95
UterusCorpus5.25
WholeBlood6.1
Wholebrain5.25
colon5.9
pineal_day7.48
pineal_night7.26
retina17.3
small_intestine5.65
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_7439_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.85 ± 0.68
Basal Forebrain3.41 ± 0.67
Basal Part of Pons3.39 ± 0.49
Cerebellar Cortex3.95 ± 0.44
Cerebellar Nuclei3.64 ± 0.34
Claustrum3.75 ± 0.8
Epithalamus3.62 ± 0.23
Frontal Lobe3.49 ± 0.64
Globus Pallidus3.56 ± 0.56
Hypothalamus3.53 ± 0.37
Insula3.28 ± 0.51
Limbic Lobe3.76 ± 0.59
Mesencephalon3.57 ± 0.61
Myelencephalon3.57 ± 0.67
Occipital Lobe3.71 ± 0.66
Parietal Lobe3.59 ± 0.6
Pontine Tegmentum3.75 ± 0.6
Striatum3.53 ± 0.63
Subthalamus3.66 ± 0.3
Temporal Lobe3.61 ± 0.63
Thalamus3.56 ± 0.84
White Matter3.83 ± 0.44
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Trim68CBCerebellum1.79
2.13
Trim68CTXCerebral cortex3.36
2.62
Trim68HIPHippocampal region5.57
5.39
Trim68HPFHippocampal formation4.85
4.5
Trim68HYHypothalamus1.54
1.57
Trim68LSXLateral septal complex0.2
0.13
Trim68MBMidbrain2
2.47
Trim68MYMedulla3.1
4.5
Trim68OLFOlfactory bulb3.83
3
Trim68PPons4.88
7.43
Trim68PALPallidum0.5
0.45
Trim68RHPRetrohippocampal region2.12
1.91
Trim68sAMYStriatum-like amygdalar nuclei2.04
1.5
Trim68STRStriatum0.75
0.63
Trim68STRdStriatum dorsal region0.32
0.37
Trim68STRvStriatum ventral region1.88
1.25
Trim68THThalamus1.24
0.95
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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