AutismKB 2.0

Annotation Detail for LARP1B


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:LARP1B ( DKFZp686L13217,LARP2,MGC117277,MGC75174 )
Gene Full Name: La ribonucleoprotein domain family, member 1B
Band: 4q28.2
Quick LinksEntrez ID:55132; OMIM: NA; Uniprot ID:LAR1B_HUMAN; ENSEMBL ID: ENSG00000138709; HGNC ID: 24704
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst1 / 6231916
fetus23 / 56401240
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult127 / 193912165
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor3 / 9417831
cervical tumor1 / 3436629
chondrosarcoma2 / 8282324
colorectal tumor1 / 1142468
esophageal tumor1 / 1729057
gastrointestinal tumor0 / 1193690 
germ cell tumor18 / 26384568
glioma2 / 10688318
head and neck tumor2 / 13630214
kidney tumor2 / 6895929
leukemia5 / 9584252
liver tumor4 / 9635941
lung tumor1 / 1031279
lymphoma1 / 7175513
non-neoplasia1 / 9725010
normal125 / 336030737
ovarian tumor3 / 7668239
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS2 / 12568015
prostate cancer3 / 10268029
retinoblastoma4 / 4635686
skin tumor2 / 12494916
soft tissue/muscle tissue tumor59 / 125191471
uterine tumor5 / 9025755
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder1 / 2975733
blood3 / 12347824
bone2 / 7165527
bone marrow1 / 4880120
brain22 / 110098919
cervix1 / 4817120
connective tissue57 / 149255381
ear0 / 162120 
embryonic tissue4 / 21572218
esophagus1 / 2020949
eye8 / 21105437
heart2 / 8962622
intestine17 / 23447272
kidney11 / 21177751
larynx0 / 241450 
liver11 / 20774352
lung8 / 33697423
lymph1 / 4427022
lymph node5 / 9161054
mammary gland8 / 15327152
mouth2 / 6705229
muscle1 / 1077159
nerve1 / 1576863
ovary4 / 10205139
pancreas6 / 21481227
parathyroid1 / 2053948
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta5 / 28082517
prostate10 / 18934552
salivary gland2 / 2015599
skin6 / 21057428
spleen0 / 539520 
stomach0 / 966190 
testis25 / 33044275
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea2 / 5241338
umbilical cord0 / 136800 
uterus11 / 23287847
vascular5 / 5178096
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P7253
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.44 ± 0.51
Basal Forebrain4.41 ± 0.23
Basal Part of Pons4.79 ± 0.5
Cerebellar Cortex4.77 ± 0.22
Cerebellar Nuclei4.24 ± 0.42
Claustrum4.56 ± 0.52
Epithalamus4.68 ± 0.46
Frontal Lobe4.57 ± 0.43
Globus Pallidus3.41 ± 0.52
Hypothalamus4.58 ± 0.53
Insula4.58 ± 0.37
Limbic Lobe4.48 ± 0.56
Mesencephalon4.42 ± 0.6
Myelencephalon4.48 ± 0.54
Occipital Lobe4.76 ± 0.4
Parietal Lobe4.66 ± 0.58
Pontine Tegmentum4.55 ± 0.53
Striatum4.12 ± 0.55
Subthalamus4.93 ± 0.6
Temporal Lobe4.66 ± 0.46
Thalamus4.43 ± 0.52
White Matter3.99 ± 0.4
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
1700108L22RikCBCerebellum1.61
2.1
1700108L22RikCTXCerebral cortex1.61
1.46
1700108L22RikHIPHippocampal region1.35
1.37
1700108L22RikHPFHippocampal formation2.68
2.57
1700108L22RikHYHypothalamus0.4
0.38
1700108L22RikLSXLateral septal complex0.08
0.08
1700108L22RikMBMidbrain0.88
1.24
1700108L22RikMYMedulla1.58
2.31
1700108L22RikOLFOlfactory bulb1.75
2.45
1700108L22RikPPons1.05
1.36
1700108L22RikPALPallidum0.19
0.21
1700108L22RikRHPRetrohippocampal region5.76
4.91
1700108L22RiksAMYStriatum-like amygdalar nuclei0.44
0.67
1700108L22RikSTRStriatum0.38
0.46
1700108L22RikSTRdStriatum dorsal region0.39
0.5
1700108L22RikSTRvStriatum ventral region0.37
0.31
1700108L22RikTHThalamus0.47
0.49
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00028770 8 771 778 YGLECLFR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018