AutismKB 2.0

Annotation Detail for TMEM38B


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Basic Information Top
Gene Symbol:TMEM38B ( C9orf87,D4Ertd89e,FLJ10493,TRIC-B,TRICB,bA219P18.1 )
Gene Full Name: transmembrane protein 38B
Band: 9q31.2
Quick LinksEntrez ID:55151; OMIM: 611236; Uniprot ID:TM38B_HUMAN; ENSEMBL ID: ENSG00000095209; HGNC ID: 25535
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus11 / 56401219
neonate1 / 3109732
infant0 / 236200 
juvenile0 / 555560 
adult61 / 193912131
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor2 / 12794156
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor1 / 3436629
chondrosarcoma1 / 8282312
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor14 / 26384553
glioma1 / 1068839
head and neck tumor3 / 13630222
kidney tumor5 / 6895972
leukemia1 / 9584210
liver tumor5 / 9635951
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia2 / 9725020
normal94 / 336030727
ovarian tumor2 / 7668226
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS2 / 12568015
prostate cancer6 / 10268058
retinoblastoma3 / 4635664
skin tumor4 / 12494932
soft tissue/muscle tissue tumor11 / 12519187
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland4 / 33197120
ascites0 / 400150 
bladder0 / 297570 
blood3 / 12347824
bone1 / 7165513
bone marrow0 / 488010 
brain58 / 110098952
cervix1 / 4817120
connective tissue11 / 14925573
ear0 / 162120 
embryonic tissue1 / 2157224
esophagus0 / 202090 
eye5 / 21105423
heart5 / 8962655
intestine4 / 23447217
kidney20 / 21177794
larynx0 / 241450 
liver11 / 20774352
lung4 / 33697411
lymph0 / 442700 
lymph node0 / 916100 
mammary gland2 / 15327113
mouth0 / 670520 
muscle7 / 10771564
nerve0 / 157680 
ovary0 / 1020510 
pancreas6 / 21481227
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta8 / 28082528
prostate8 / 18934542
salivary gland0 / 201550 
skin4 / 21057418
spleen0 / 539520 
stomach1 / 9661910
testis31 / 33044293
thymus0 / 811310 
thyroid3 / 4747363
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus3 / 23287812
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 218772_x_at
Cell line Expression level Expression bar
721_B_lymphoblasts15.05
Adipocyte5.05
AdrenalCortex5.6
Adrenalgland4.7
Amygdala5.3
Appendix6.05
AtrioventricularNode4.25
BDCA4+_DentriticCells7.55
Bonemarrow5.2
BronchialEpithelialCells5.05
CD105+_Endothelial5.3
CD14+_Monocytes5.65
CD19+_BCells(neg._sel.)12.2
CD33+_Myeloid7.2
CD34+7.6
CD4+_Tcells5.45
CD56+_NKCells7.05
CD71+_EarlyErythroid4.95
CD8+_Tcells4.95
CardiacMyocytes7.1
Caudatenucleus4.65
Cerebellum4.2
CerebellumPeduncles5.95
CiliaryGanglion4.25
CingulateCortex5.25
Colorectaladenocarcinoma10.8
DorsalRootGanglion4.1
FetalThyroid5.2
Fetalbrain5
Fetalliver4.6
Fetallung4
GlobusPallidus3.9
Heart7
Hypothalamus5.5
Kidney4.55
Leukemia_chronicMyelogenousK-5624.7
Leukemia_promyelocytic-HL-604.65
Leukemialymphoblastic(MOLT-4)4.15
Liver7
Lung5.6
Lymphnode4.3
Lymphoma_burkitts(Daudi)7.1
Lymphoma_burkitts(Raji)7.85
MedullaOblongata4.6
OccipitalLobe4.6
OlfactoryBulb4
Ovary3.75
Pancreas4.2
PancreaticIslet5.6
ParietalLobe5.55
Pituitary6.2
Placenta5.1
Pons5
PrefrontalCortex6.25
Prostate5.95
Salivarygland4.2
SkeletalMuscle6.2
Skin4.15
SmoothMuscle5.8
Spinalcord5.55
SubthalamicNucleus4.85
SuperiorCervicalGanglion6.4
TemporalLobe4.75
Testis4.4
TestisGermCell4.2
TestisIntersitial4.35
TestisLeydigCell5.35
TestisSeminiferousTubule4.4
Thalamus5.3
Thymus3.9
Thyroid11.45
Tongue5.2
Tonsil5
Trachea4.25
TrigeminalGanglion6.05
Uterus4.1
UterusCorpus4.7
WholeBlood5.55
Wholebrain4.25
colon16.85
pineal_day131.78
pineal_night99.04
retina15.4
small_intestine18.55
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P278156
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.34 ± 0.4
Basal Forebrain5.82 ± 0.28
Basal Part of Pons5.54 ± 0.5
Cerebellar Cortex5.62 ± 0.3
Cerebellar Nuclei6.13 ± 0.5
Claustrum4.96 ± 0.47
Epithalamus5.99 ± 0.51
Frontal Lobe5.42 ± 0.56
Globus Pallidus6.57 ± 0.47
Hypothalamus5.85 ± 0.54
Insula5.27 ± 0.27
Limbic Lobe5.28 ± 0.54
Mesencephalon5.7 ± 0.53
Myelencephalon5.53 ± 0.58
Occipital Lobe5.68 ± 0.58
Parietal Lobe5.45 ± 0.51
Pontine Tegmentum5.72 ± 0.31
Striatum5.98 ± 0.51
Subthalamus5.65 ± 1.07
Temporal Lobe5.29 ± 0.44
Thalamus5.76 ± 0.44
White Matter7.7 ± 0.35
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Tmem38bCBCerebellum1.96
2.44
Tmem38bCTXCerebral cortex3
2.29
Tmem38bHIPHippocampal region9.85
9.58
Tmem38bHPFHippocampal formation8.81
7.97
Tmem38bHYHypothalamus11.74
10.55
Tmem38bLSXLateral septal complex1.39
1.73
Tmem38bMBMidbrain4.92
4.73
Tmem38bMYMedulla6.3
7.16
Tmem38bOLFOlfactory bulb9.2
8.25
Tmem38bPPons12.43
14.36
Tmem38bPALPallidum7.35
6.14
Tmem38bRHPRetrohippocampal region6.05
4.23
Tmem38bsAMYStriatum-like amygdalar nuclei1.54
1.2
Tmem38bSTRStriatum3.23
2.61
Tmem38bSTRdStriatum dorsal region0.78
0.74
Tmem38bSTRvStriatum ventral region13.21
9.28
Tmem38bTHThalamus3.45
2.87
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00037826 22 262 283 SPSNGVGSLASKPVDVASDNVK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018