AutismKB 2.0

Annotation Detail for INTS10


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Basic Information Top
Gene Symbol:INTS10 ( C8orf35,FLJ10569,INT10 )
Gene Full Name: integrator complex subunit 10
Band: 8p21.3
Quick LinksEntrez ID:55174; OMIM: 611353; Uniprot ID:INT10_HUMAN; ENSEMBL ID: ENSG00000104613; HGNC ID: 25548
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst4 / 6231964
fetus44 / 56401278
neonate2 / 3109764
infant0 / 236200 
juvenile4 / 5555671
adult124 / 193912163
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor3 / 9417831
cervical tumor3 / 3436687
chondrosarcoma10 / 82823120
colorectal tumor7 / 11424661
esophageal tumor1 / 1729057
gastrointestinal tumor8 / 11936967
germ cell tumor21 / 26384579
glioma12 / 106883112
head and neck tumor4 / 13630229
kidney tumor3 / 6895943
leukemia6 / 9584262
liver tumor1 / 9635910
lung tumor8 / 10312777
lymphoma3 / 7175541
non-neoplasia4 / 9725041
normal224 / 336030766
ovarian tumor6 / 7668278
pancreatic tumor5 / 10461647
primitive neuroectodermal tumor of the CNS10 / 12568079
prostate cancer12 / 102680116
retinoblastoma2 / 4635643
skin tumor9 / 12494972
soft tissue/muscle tissue tumor5 / 12519139
uterine tumor5 / 9025755
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland1 / 3319730
ascites6 / 40015149
bladder2 / 2975767
blood8 / 12347864
bone3 / 7165541
bone marrow4 / 4880181
brain95 / 110098986
cervix4 / 4817183
connective tissue8 / 14925553
ear0 / 162120 
embryonic tissue7 / 21572232
esophagus1 / 2020949
eye17 / 21105480
heart7 / 8962678
intestine14 / 23447259
kidney8 / 21177737
larynx1 / 2414541
liver5 / 20774324
lung25 / 33697474
lymph2 / 4427045
lymph node9 / 9161098
mammary gland7 / 15327145
mouth0 / 670520 
muscle3 / 10771527
nerve0 / 157680 
ovary8 / 10205178
pancreas13 / 21481260
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland1 / 1658560
placenta18 / 28082564
prostate22 / 189345116
salivary gland2 / 2015599
skin11 / 21057452
spleen4 / 5395274
stomach1 / 9661910
testis12 / 33044236
thymus7 / 8113186
thyroid1 / 4747321
tonsil0 / 169990 
trachea4 / 5241376
umbilical cord2 / 13680146
uterus17 / 23287872
vascular3 / 5178057
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: Primary tumors (U95A)
  • Affymatrix Probe ID: 38226_at
Cell line Expression level Expression bar
Pr1T140.308
Pr4T91.275
Pr5T84.696
Pr7T99.56
Pr1N112.579
Pr5N71.735
Pr6T264.114
Pr3N48.403
Pr3T53.776
Pr4N89.337
Pr2N64.629
Pr8N86.522
Pr8T85.433
Pr9N94.36
Pr10N66.146
Pr10T97.59
Pr9T75.008
Pr11T296.245
Pr12T86.176
Pr13AT138.03
Pr13BT153.106
Pr21T169.268
Pr22T56.395
Pr30T78.835
Pr23T62.56
Pr19T68.788
Pr26T54.089
Pr31T118.591
Pr16T62.267
Pr17T57.85
Pr24T48.214
Pr27T156.235
Pr29T265.207
OVR102101.479
HUOVR101.882
G2135.34
G3108.65
G569.988
G655.431
G851.382
G962.876
CO7T91.943
CO8T53.281
CO15T68.971
CO27T97.222
CO30T83.454
CO32T100.935
CO40T74.527
CO52N97.155
CO62N63.739
K145.506
K242.323
K338.166
K454.135
K14N70.653
K1655.916
K1761.042
K1948.103
K2057.688
K2251.5
CO9T48.703
CO20T58.722
CO24T66.529
CO36N70.815
K1839.01
P1N48.137
P2N96.492
P5N61.95
P853.713
P1133.24
P1762.806
K2149.252
K25N62.388
K28N53.595
CO42T58.41
P2244.787
P13N50.107
LU11T49.651
LU16T51.595
LU7T52.71
LU8T41.03
LU12T60.575
LU13T66.16
LU5T51.735
LU6T60.433
LU14T56.71
LU17T47.022
LU50N48.133
LU52N54.108
LU18T61.031
LU55N57.423
LU3N61.252
P16B64.342
P2354.77
OVR1640.188
OVR19166.819
OVR2729.475
OVR2840.783
OVR278E59.503
OVR240.48
OVR535.691
OVR859.174
OVR1131.321
OVR1294.285
OVR1344.332
OVR2249.082
OVR2654.253
OVR1070.086
OVR278S64.335
OVR171.518
LU19T53.464
LU20T63.094
LU24T41.888
LU25T135.076
LU31T95.183
LU34T59.016
LU39T99.53
CO14T62.088
CO21T47.916
CO23T61.059
CO41N54.359
LU40T67.932
LU41T51.827
LU44T64.19
LU46T50.65
LU49T65.452
L5N59.212
LU42T59.64
LU30T99.163
LU43T82.158
CO5T145.259
CO44T514.145
CO49T82.844
CO51T78.287
CO56T53.853
CO61T107.289
LU26T56.942
LU33T56.986
LU36T49.363
CO43T77.118
G18144.201
G4656.486
L11T69.496
L13N92.47
L30T61.544
L31T54.571
L32T51.243
L34T70.943
L35T56.681
B1N93.386
B5N54.485
B8T46.888
B10T57.115
B14T58.448
B16T50.611
B17T60.212
B1NR63.23
B20T57.678
B51NR47.402
B6T75.755
B15T72.44
B21T67.68
B29T51.618
B31T67.674
B32T58.282
B24T54.724
B46T53.877
B34T49.308
B36T52.864
B37T88.622
B38T59.304
B39T54.829
X10251.824
X116_0279.332
G28054.649
X4641.018
X5838.695
G18659.859
G29671.573
L38T56.23
L31T.2244.507
L26N66.396
N257ANTR104.536
N285BODY49.007
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_11157_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.97 ± 0.3
Basal Forebrain6.95 ± 0.13
Basal Part of Pons7 ± 0.24
Cerebellar Cortex7.2 ± 0.21
Cerebellar Nuclei6.76 ± 0.27
Claustrum6.53 ± 0.58
Epithalamus7.26 ± 0.33
Frontal Lobe6.99 ± 0.29
Globus Pallidus6.69 ± 0.2
Hypothalamus6.85 ± 0.29
Insula7.04 ± 0.22
Limbic Lobe7.01 ± 0.31
Mesencephalon6.96 ± 0.28
Myelencephalon6.92 ± 0.34
Occipital Lobe6.94 ± 0.34
Parietal Lobe6.93 ± 0.3
Pontine Tegmentum6.86 ± 0.36
Striatum6.85 ± 0.32
Subthalamus6.9 ± 0.13
Temporal Lobe7.04 ± 0.3
Thalamus6.8 ± 0.28
White Matter7.31 ± 0.32
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Ints10CBCerebellum45.33
52.02
Ints10CTXCerebral cortex100
100
Ints10HIPHippocampal region88.48
100
Ints10HPFHippocampal formation100
100
Ints10HYHypothalamus50.4
36.5
Ints10LSXLateral septal complex100
77.43
Ints10MBMidbrain62.53
53.64
Ints10MYMedulla63.19
63.95
Ints10OLFOlfactory bulb100
100
Ints10PPons58.02
54.59
Ints10PALPallidum69.93
59.54
Ints10RHPRetrohippocampal region100
100
Ints10sAMYStriatum-like amygdalar nuclei99.95
74.41
Ints10STRStriatum100
78.72
Ints10STRdStriatum dorsal region95.75
69.41
Ints10STRvStriatum ventral region100
100
Ints10THThalamus86.33
79.04
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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