AutismKB 2.0

Annotation Detail for FAM82A2


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Basic Information Top
Gene Symbol:FAM82A2 ( FAM82C,FLJ10579,RMD3,hRMD-3,ptpip51 )
Gene Full Name: family with sequence similarity 82, member A2
Band: 15q15.1
Quick LinksEntrez ID:55177; OMIM: 611873; Uniprot ID:RMD3_HUMAN; ENSEMBL ID: ENSG00000137824; HGNC ID:
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body4 / 7076156
blastocyst2 / 6231932
fetus41 / 56401272
neonate7 / 31097225
infant3 / 23620127
juvenile13 / 55556233
adult148 / 193912176
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor2 / 12794156
bladder carcinoma0 / 174750 
breast (mammary gland) tumor10 / 94178106
cervical tumor5 / 34366145
chondrosarcoma1 / 8282312
colorectal tumor4 / 11424635
esophageal tumor0 / 172900 
gastrointestinal tumor6 / 11936950
germ cell tumor21 / 26384579
glioma14 / 106883130
head and neck tumor9 / 13630266
kidney tumor13 / 68959188
leukemia13 / 95842135
liver tumor8 / 9635983
lung tumor6 / 10312758
lymphoma4 / 7175555
non-neoplasia15 / 97250154
normal348 / 3360307103
ovarian tumor13 / 76682169
pancreatic tumor22 / 104616210
primitive neuroectodermal tumor of the CNS33 / 125680262
prostate cancer15 / 102680146
retinoblastoma4 / 4635686
skin tumor10 / 12494980
soft tissue/muscle tissue tumor4 / 12519131
uterine tumor4 / 9025744
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland6 / 33197180
ascites2 / 4001549
bladder2 / 2975767
blood13 / 123478105
bone2 / 7165527
bone marrow2 / 4880140
brain213 / 1100989193
cervix9 / 48171186
connective tissue9 / 14925560
ear2 / 16212123
embryonic tissue10 / 21572246
esophagus0 / 202090 
eye8 / 21105437
heart10 / 89626111
intestine20 / 23447285
kidney34 / 211777160
larynx0 / 241450 
liver13 / 20774362
lung38 / 336974112
lymph2 / 4427045
lymph node1 / 9161010
mammary gland12 / 15327178
mouth4 / 6705259
muscle25 / 107715232
nerve0 / 157680 
ovary22 / 102051215
pancreas23 / 214812107
parathyroid1 / 2053948
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta20 / 28082571
prostate18 / 18934595
salivary gland8 / 20155396
skin16 / 21057475
spleen8 / 53952148
stomach7 / 9661972
testis16 / 33044248
thymus6 / 8113173
thyroid0 / 474730 
tonsil1 / 1699958
trachea5 / 5241395
umbilical cord1 / 1368073
uterus12 / 23287851
vascular6 / 51780115
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 218126_at
Cell line Expression level Expression bar
721_B_lymphoblasts93.2
Adipocyte85.65
AdrenalCortex56.7
Adrenalgland64.05
Amygdala111.05
Appendix51.9
AtrioventricularNode28.45
BDCA4+_DentriticCells123.05
Bonemarrow50.25
BronchialEpithelialCells55.7
CD105+_Endothelial205.6
CD14+_Monocytes43.25
CD19+_BCells(neg._sel.)35.15
CD33+_Myeloid49.15
CD34+50.05
CD4+_Tcells56
CD56+_NKCells149.25
CD71+_EarlyErythroid874.75
CD8+_Tcells74.5
CardiacMyocytes49.4
Caudatenucleus82.85
Cerebellum115.45
CerebellumPeduncles91.8
CiliaryGanglion25.5
CingulateCortex90.1
Colorectaladenocarcinoma36.3
DorsalRootGanglion30.65
FetalThyroid61.2
Fetalbrain54.7
Fetalliver115
Fetallung59.95
GlobusPallidus59.05
Heart50.6
Hypothalamus150.2
Kidney54.5
Leukemia_chronicMyelogenousK-56245.45
Leukemia_promyelocytic-HL-6040.5
Leukemialymphoblastic(MOLT-4)51.45
Liver58.75
Lung171.2
Lymphnode78.5
Lymphoma_burkitts(Daudi)53
Lymphoma_burkitts(Raji)71.35
MedullaOblongata128.7
OccipitalLobe72.9
OlfactoryBulb104.6
Ovary45.5
Pancreas32.75
PancreaticIslet55.95
ParietalLobe63
Pituitary64.8
Placenta107
Pons48.6
PrefrontalCortex123.85
Prostate62.7
Salivarygland44.6
SkeletalMuscle57.65
Skin29.95
SmoothMuscle50.8
Spinalcord139.8
SubthalamicNucleus85.3
SuperiorCervicalGanglion57
TemporalLobe80.65
Testis54.9
TestisGermCell53.9
TestisIntersitial50.4
TestisLeydigCell55.05
TestisSeminiferousTubule43.65
Thalamus81.4
Thymus51.6
Thyroid78.9
Tongue63.6
Tonsil50.3
Trachea52.35
TrigeminalGanglion50.15
Uterus47.7
UterusCorpus45.4
WholeBlood52.6
Wholebrain227.1
colon58.8
pineal_day125.76
pineal_night106.86
retina113.75
small_intestine71.15
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P296280
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.29 ± 0.72
Basal Forebrain4.32 ± 0.44
Basal Part of Pons5.03 ± 0.32
Cerebellar Cortex4.99 ± 0.42
Cerebellar Nuclei4.82 ± 0.37
Claustrum4.21 ± 0.77
Epithalamus4.88 ± 0.4
Frontal Lobe4.73 ± 0.5
Globus Pallidus4.41 ± 0.45
Hypothalamus4.31 ± 0.68
Insula4.7 ± 0.4
Limbic Lobe4.54 ± 0.53
Mesencephalon4.58 ± 0.5
Myelencephalon4.64 ± 0.51
Occipital Lobe4.62 ± 0.43
Parietal Lobe4.64 ± 0.52
Pontine Tegmentum4.64 ± 0.6
Striatum4.03 ± 0.49
Subthalamus5.51 ± 1.31
Temporal Lobe4.81 ± 0.39
Thalamus4.73 ± 0.49
White Matter4.84 ± 0.33
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
1200015F23RikCBCerebellum17.69
24.25
1200015F23RikCTXCerebral cortex5.2
4.36
1200015F23RikHIPHippocampal region2.66
2.77
1200015F23RikHPFHippocampal formation3.14
2.81
1200015F23RikHYHypothalamus0.1
0.11
1200015F23RikLSXLateral septal complex0.17
0.15
1200015F23RikMBMidbrain0.44
0.63
1200015F23RikMYMedulla3.27
3.31
1200015F23RikOLFOlfactory bulb2.45
3.38
1200015F23RikPPons0.23
0.19
1200015F23RikPALPallidum0.82
0.75
1200015F23RikRHPRetrohippocampal region4.02
2.97
1200015F23RiksAMYStriatum-like amygdalar nuclei0.77
1.02
1200015F23RikSTRStriatum2.28
2.1
1200015F23RikSTRdStriatum dorsal region3.35
3.1
1200015F23RikSTRvStriatum ventral region0.36
0.32
1200015F23RikTHThalamus0.54
0.55
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00000422 17 355 371 AIALQPENPMAHFLLGR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018