AutismKB 2.0

Annotation Detail for LINS


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:LINS ( FLJ10583,LINS1,WINS1 )
Gene Full Name: lines homolog (Drosophila)
Band: 15q26.3
Quick LinksEntrez ID:55180; OMIM: 610350; Uniprot ID:LINES_HUMAN; ENSEMBL ID: ENSG00000140471; HGNC ID:
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst0 / 623190 
fetus29 / 56401251
neonate3 / 3109796
infant2 / 2362084
juvenile2 / 5555635
adult40 / 193912120
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor1 / 1142468
esophageal tumor1 / 1729057
gastrointestinal tumor1 / 1193698
germ cell tumor9 / 26384534
glioma0 / 1068830 
head and neck tumor3 / 13630222
kidney tumor1 / 6895914
leukemia2 / 9584220
liver tumor2 / 9635920
lung tumor1 / 1031279
lymphoma1 / 7175513
non-neoplasia2 / 9725020
normal108 / 336030732
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS7 / 12568055
prostate cancer2 / 10268019
retinoblastoma1 / 4635621
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites1 / 4001524
bladder0 / 297570 
blood7 / 12347856
bone3 / 7165541
bone marrow1 / 4880120
brain22 / 110098919
cervix0 / 481710 
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue3 / 21572213
esophagus1 / 2020949
eye8 / 21105437
heart1 / 8962611
intestine2 / 2344728
kidney12 / 21177756
larynx0 / 241450 
liver2 / 2077439
lung6 / 33697417
lymph1 / 4427022
lymph node6 / 9161065
mammary gland2 / 15327113
mouth4 / 6705259
muscle0 / 1077150 
nerve1 / 1576863
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid2 / 2053997
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta8 / 28082528
prostate2 / 18934510
salivary gland0 / 201550 
skin2 / 2105749
spleen5 / 5395292
stomach0 / 966190 
testis12 / 33044236
thymus5 / 8113161
thyroid1 / 4747321
tonsil0 / 169990 
trachea5 / 5241395
umbilical cord0 / 136800 
uterus6 / 23287825
vascular3 / 5178057
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P205944
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.79 ± 0.61
Basal Forebrain4.53 ± 0.45
Basal Part of Pons4.74 ± 0.21
Cerebellar Cortex5.18 ± 0.21
Cerebellar Nuclei4.62 ± 0.42
Claustrum4.25 ± 0.81
Epithalamus4.79 ± 0.61
Frontal Lobe4.76 ± 0.45
Globus Pallidus3.86 ± 0.46
Hypothalamus4.71 ± 0.61
Insula5.01 ± 0.35
Limbic Lobe4.59 ± 0.55
Mesencephalon4.82 ± 0.51
Myelencephalon4.64 ± 0.52
Occipital Lobe4.82 ± 0.51
Parietal Lobe4.72 ± 0.5
Pontine Tegmentum4.71 ± 0.52
Striatum4.68 ± 0.43
Subthalamus4.59 ± 0.25
Temporal Lobe4.86 ± 0.48
Thalamus4.7 ± 0.48
White Matter4.73 ± 0.3
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Lins2CBCerebellum1.41
2.41
Lins2CTXCerebral cortex1.21
0.67
Lins2HIPHippocampal region0.6
0.54
Lins2HPFHippocampal formation0.71
0.53
Lins2HYHypothalamus0.16
0.14
Lins2LSXLateral septal complex0.5
0.41
Lins2MBMidbrain1.34
2.03
Lins2MYMedulla0.65
0.42
Lins2OLFOlfactory bulb2.23
1.09
Lins2PPons0.63
0.6
Lins2PALPallidum0.13
0.19
Lins2RHPRetrohippocampal region0.82
0.5
Lins2sAMYStriatum-like amygdalar nuclei0.44
0.16
Lins2STRStriatum0.24
0.14
Lins2STRdStriatum dorsal region0.18
0.12
Lins2STRvStriatum ventral region0.19
0.08
Lins2THThalamus1.88
2.47
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00036250 18 334 351 MLALANAVLQAVNSGLLK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018