AutismKB 2.0

Annotation Detail for RNF220


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Basic Information Top
Gene Symbol:RNF220 ( C1orf164,FLJ10597 )
Gene Full Name: ring finger protein 220
Band: 1p34.1
Quick LinksEntrez ID:55182; OMIM: NA; Uniprot ID:RN220_HUMAN; ENSEMBL ID: ENSG00000187147; HGNC ID: 25552
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body5 / 7076170
blastocyst4 / 6231964
fetus45 / 56401279
neonate0 / 310970 
infant1 / 2362042
juvenile5 / 5555689
adult203 / 1939121104
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor5 / 9417853
cervical tumor2 / 3436658
chondrosarcoma5 / 8282360
colorectal tumor27 / 114246236
esophageal tumor2 / 17290115
gastrointestinal tumor21 / 119369175
germ cell tumor33 / 263845125
glioma5 / 10688346
head and neck tumor13 / 13630295
kidney tumor15 / 68959217
leukemia21 / 95842219
liver tumor0 / 963590 
lung tumor16 / 103127155
lymphoma4 / 7175555
non-neoplasia3 / 9725030
normal417 / 3360307124
ovarian tumor15 / 76682195
pancreatic tumor9 / 10461686
primitive neuroectodermal tumor of the CNS6 / 12568047
prostate cancer5 / 10268048
retinoblastoma8 / 46356172
skin tumor10 / 12494980
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor14 / 90257155
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland2 / 3319760
ascites7 / 40015174
bladder0 / 297570 
blood21 / 123478170
bone4 / 7165555
bone marrow1 / 4880120
brain229 / 1100989207
cervix4 / 4817183
connective tissue4 / 14925526
ear0 / 162120 
embryonic tissue12 / 21572255
esophagus2 / 2020998
eye18 / 21105485
heart12 / 89626133
intestine43 / 234472183
kidney29 / 211777136
larynx3 / 24145124
liver2 / 2077439
lung40 / 336974118
lymph0 / 442700 
lymph node10 / 91610109
mammary gland7 / 15327145
mouth0 / 670520 
muscle1 / 1077159
nerve0 / 157680 
ovary17 / 102051166
pancreas19 / 21481288
parathyroid0 / 205390 
pharynx5 / 41328120
pituitary gland1 / 1658560
placenta23 / 28082581
prostate9 / 18934547
salivary gland3 / 20155148
skin20 / 21057494
spleen2 / 5395237
stomach14 / 96619144
testis41 / 330442124
thymus1 / 8113112
thyroid2 / 4747342
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus20 / 23287885
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 219988_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts204
Adipocyte71.95
AdrenalCortex85.2
Adrenalgland76.15
Amygdala303.9
Appendix91.6
AtrioventricularNode62.9
BDCA4+_DentriticCells200.95
Bonemarrow141.6
BronchialEpithelialCells56
CD105+_Endothelial227.5
CD14+_Monocytes239.35
CD19+_BCells(neg._sel.)354.45
CD33+_Myeloid203.55
CD34+180.75
CD4+_Tcells254.35
CD56+_NKCells196.55
CD71+_EarlyErythroid220.55
CD8+_Tcells263.65
CardiacMyocytes63.35
Caudatenucleus239.35
Cerebellum194.15
CerebellumPeduncles251.95
CiliaryGanglion63.3
CingulateCortex216.15
Colorectaladenocarcinoma89.55
DorsalRootGanglion56.35
FetalThyroid104.45
Fetalbrain170.4
Fetalliver71.7
Fetallung69
GlobusPallidus121.95
Heart97.2
Hypothalamus338.1
Kidney65.8
Leukemia_chronicMyelogenousK-562123.75
Leukemia_promyelocytic-HL-60143.95
Leukemialymphoblastic(MOLT-4)168.45
Liver77.65
Lung97.4
Lymphnode82.15
Lymphoma_burkitts(Daudi)209.1
Lymphoma_burkitts(Raji)176.85
MedullaOblongata227.35
OccipitalLobe273.95
OlfactoryBulb84.6
Ovary47.95
Pancreas78.1
PancreaticIslet88.1
ParietalLobe261.95
Pituitary100.8
Placenta86.95
Pons160.25
PrefrontalCortex528.4
Prostate98.5
Salivarygland68.55
SkeletalMuscle101.85
Skin62.7
SmoothMuscle58.05
Spinalcord310.15
SubthalamicNucleus153.05
SuperiorCervicalGanglion91.75
TemporalLobe194
Testis126.65
TestisGermCell123.35
TestisIntersitial116.1
TestisLeydigCell81.2
TestisSeminiferousTubule124.45
Thalamus319.45
Thymus103.8
Thyroid120.85
Tongue64.8
Tonsil80.1
Trachea67.7
TrigeminalGanglion75.35
Uterus83.8
UterusCorpus73.35
WholeBlood196.2
Wholebrain591.95
colon74.9
pineal_day327.72
pineal_night278.56
retina280.3
small_intestine67.95
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P424401
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala8.78 ± 0.45
Basal Forebrain9.31 ± 0.16
Basal Part of Pons9.54 ± 0.27
Cerebellar Cortex9.33 ± 0.26
Cerebellar Nuclei9.72 ± 0.16
Claustrum8.99 ± 0.52
Epithalamus9.23 ± 0.31
Frontal Lobe9.57 ± 0.31
Globus Pallidus9.31 ± 0.29
Hypothalamus9.31 ± 0.31
Insula9.44 ± 0.22
Limbic Lobe9.15 ± 0.35
Mesencephalon9.31 ± 0.34
Myelencephalon9.41 ± 0.38
Occipital Lobe9.11 ± 0.38
Parietal Lobe9.52 ± 0.37
Pontine Tegmentum9.41 ± 0.4
Striatum8.93 ± 0.35
Subthalamus9.59 ± 0.16
Temporal Lobe9.47 ± 0.28
Thalamus9.63 ± 0.37
White Matter10.45 ± 0.23
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
4931406I20RikCBCerebellum33.81
46.15
4931406I20RikCTXCerebral cortex98.74
94.05
4931406I20RikHIPHippocampal region77.45
100
4931406I20RikHPFHippocampal formation85.14
98.1
4931406I20RikHYHypothalamus46.47
45.77
4931406I20RikLSXLateral septal complex60.23
49.1
4931406I20RikMBMidbrain66.22
71.36
4931406I20RikMYMedulla69.27
87.71
4931406I20RikOLFOlfactory bulb80.24
80.25
4931406I20RikPPons67.09
80.25
4931406I20RikPALPallidum51.42
54.02
4931406I20RikRHPRetrohippocampal region88.93
87.08
4931406I20RiksAMYStriatum-like amygdalar nuclei53.26
46.41
4931406I20RikSTRStriatum54.16
44.4
4931406I20RikSTRdStriatum dorsal region53.09
43.48
4931406I20RikSTRvStriatum ventral region57.7
45.06
4931406I20RikTHThalamus100
100
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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