Annotation Detail for RIF1
Basic Information Top
| Gene Symbol: | RIF1 ( DKFZp434D1026,DKFZp781N1478,FLJ12870 ) |
|---|---|
| Gene Full Name: | RAP1 interacting factor homolog (yeast) |
| Band: | 2q23.3 |
| Quick Links | Entrez ID:55183; OMIM: 608952; Uniprot ID:RIF1_HUMAN; ENSEMBL ID: ENSG00000080345; HGNC ID: 23207 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.725538
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 3 / 70761 | 42 |  |
| blastocyst | 7 / 62319 | 112 |  |
| fetus | 21 / 564012 | 37 | |
| neonate | 0 / 31097 | 0 | |
| infant | 1 / 23620 | 42 | |
| juvenile | 0 / 55556 | 0 | |
| adult | 83 / 1939121 | 42 | |
| embryoid body | 0 / 70761 | 0 | |
| blastocyst | 0 / 62319 | 0 | |
| fetus | 0 / 564012 | 0 | |
| neonate | 0 / 31097 | 0 | |
| infant | 0 / 23620 | 0 | |
| juvenile | 0 / 55556 | 0 | |
| adult | 1 / 1939121 | 0 |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 2 / 17475 | 114 | |
| breast (mammary gland) tumor | 2 / 94178 | 21 | |
| cervical tumor | 0 / 34366 | 0 | |
| chondrosarcoma | 1 / 82823 | 12 | |
| colorectal tumor | 4 / 114246 | 35 | |
| esophageal tumor | 0 / 17290 | 0 | |
| gastrointestinal tumor | 5 / 119369 | 41 | |
| germ cell tumor | 21 / 263845 | 79 | |
| glioma | 1 / 106883 | 9 |  |
| head and neck tumor | 9 / 136302 | 66 | |
| kidney tumor | 5 / 68959 | 72 | |
| leukemia | 5 / 95842 | 52 | |
| liver tumor | 3 / 96359 | 31 | |
| lung tumor | 2 / 103127 | 19 | |
| lymphoma | 3 / 71755 | 41 | |
| non-neoplasia | 4 / 97250 | 41 | |
| normal | 113 / 3360307 | 33 | |
| ovarian tumor | 3 / 76682 | 39 | |
| pancreatic tumor | 1 / 104616 | 9 | |
| primitive neuroectodermal tumor of the CNS | 1 / 125680 | 7 | |
| prostate cancer | 2 / 102680 | 19 | |
| retinoblastoma | 5 / 46356 | 107 | |
| skin tumor | 3 / 124949 | 24 | |
| soft tissue/muscle tissue tumor | 6 / 125191 | 47 | |
| uterine tumor | 1 / 90257 | 11 | |
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 0 / 17475 | 0 | |
| breast (mammary gland) tumor | 0 / 94178 | 0 | |
| cervical tumor | 0 / 34366 | 0 | |
| chondrosarcoma | 0 / 82823 | 0 | |
| colorectal tumor | 0 / 114246 | 0 | |
| esophageal tumor | 0 / 17290 | 0 | |
| gastrointestinal tumor | 0 / 119369 | 0 | |
| germ cell tumor | 0 / 263845 | 0 | |
| glioma | 0 / 106883 | 0 | |
| head and neck tumor | 0 / 136302 | 0 | |
| kidney tumor | 0 / 68959 | 0 | |
| leukemia | 0 / 95842 | 0 | |
| liver tumor | 0 / 96359 | 0 | |
| lung tumor | 0 / 103127 | 0 | |
| lymphoma | 0 / 71755 | 0 | |
| non-neoplasia | 0 / 97250 | 0 | |
| normal | 4 / 3360307 | 1 |  |
| ovarian tumor | 0 / 76682 | 0 | |
| pancreatic tumor | 0 / 104616 | 0 | |
| primitive neuroectodermal tumor of the CNS | 0 / 125680 | 0 | |
| prostate cancer | 0 / 102680 | 0 | |
| retinoblastoma | 0 / 46356 | 0 | |
| skin tumor | 0 / 124949 | 0 | |
| soft tissue/muscle tissue tumor | 0 / 125191 | 0 | |
| uterine tumor | 0 / 90257 | 0 |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 0 / 13106 | 0 | |
| adrenal gland | 0 / 33197 | 0 | |
| ascites | 0 / 40015 | 0 | |
| bladder | 2 / 29757 | 67 | |
| blood | 11 / 123478 | 89 | |
| bone | 2 / 71655 | 27 | |
| bone marrow | 2 / 48801 | 40 | |
| brain | 26 / 1100989 | 23 | |
| cervix | 0 / 48171 | 0 | |
| connective tissue | 3 / 149255 | 20 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 18 / 215722 | 83 | |
| esophagus | 0 / 20209 | 0 | |
| eye | 11 / 211054 | 52 | |
| heart | 2 / 89626 | 22 | |
| intestine | 6 / 234472 | 25 | |
| kidney | 11 / 211777 | 51 | |
| larynx | 0 / 24145 | 0 | |
| liver | 14 / 207743 | 67 | |
| lung | 6 / 336974 | 17 | |
| lymph | 3 / 44270 | 67 | |
| lymph node | 4 / 91610 | 43 | |
| mammary gland | 5 / 153271 | 32 | |
| mouth | 6 / 67052 | 89 | |
| muscle | 2 / 107715 | 18 | |
| nerve | 1 / 15768 | 63 | |
| ovary | 4 / 102051 | 39 | |
| pancreas | 4 / 214812 | 18 | |
| parathyroid | 0 / 20539 | 0 | |
| pharynx | 0 / 41328 | 0 | |
| pituitary gland | 0 / 16585 | 0 | |
| placenta | 4 / 280825 | 14 | |
| prostate | 7 / 189345 | 36 | |
| salivary gland | 0 / 20155 | 0 | |
| skin | 7 / 210574 | 33 | |
| spleen | 0 / 53952 | 0 | |
| stomach | 3 / 96619 | 31 | |
| testis | 21 / 330442 | 63 | |
| thymus | 0 / 81131 | 0 | |
| thyroid | 4 / 47473 | 84 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 3 / 52413 | 57 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 4 / 232878 | 17 | |
| vascular | 1 / 51780 | 19 | |
| adipose tissue | 0 / 13106 | 0 | |
| adrenal gland | 0 / 33197 | 0 | |
| ascites | 0 / 40015 | 0 | |
| bladder | 0 / 29757 | 0 | |
| blood | 0 / 123478 | 0 | |
| bone | 0 / 71655 | 0 | |
| bone marrow | 0 / 48801 | 0 | |
| brain | 1 / 1100989 | 0 | |
| cervix | 0 / 48171 | 0 | |
| connective tissue | 0 / 149255 | 0 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 0 / 215722 | 0 | |
| esophagus | 0 / 20209 | 0 | |
| eye | 0 / 211054 | 0 | |
| heart | 0 / 89626 | 0 | |
| intestine | 0 / 234472 | 0 | |
| kidney | 0 / 211777 | 0 | |
| larynx | 0 / 24145 | 0 | |
| liver | 0 / 207743 | 0 | |
| lung | 0 / 336974 | 0 | |
| lymph | 0 / 44270 | 0 | |
| lymph node | 0 / 91610 | 0 | |
| mammary gland | 1 / 153271 | 6 | |
| mouth | 0 / 67052 | 0 | |
| muscle | 0 / 107715 | 0 | |
| nerve | 0 / 15768 | 0 | |
| ovary | 0 / 102051 | 0 | |
| pancreas | 0 / 214812 | 0 | |
| parathyroid | 0 / 20539 | 0 | |
| pharynx | 0 / 41328 | 0 | |
| pituitary gland | 0 / 16585 | 0 | |
| placenta | 0 / 280825 | 0 | |
| prostate | 0 / 189345 | 0 | |
| salivary gland | 0 / 20155 | 0 | |
| skin | 0 / 210574 | 0 | |
| spleen | 0 / 53952 | 0 | |
| stomach | 0 / 96619 | 0 | |
| testis | 2 / 330442 | 6 | |
| thymus | 0 / 81131 | 0 | |
| thyroid | 0 / 47473 | 0 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 0 / 52413 | 0 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 0 / 232878 | 0 | |
| vascular | 0 / 51780 | 0 |
- Microarray Platform: GeneAtlas U133A, gcrma
- Affymatrix Probe ID: 214700_x_at
| Cell line | Expression level | Expression bar |
|---|---|---|
| ||
| 721_B_lymphoblasts | 49.8 | |
| Adipocyte | 7.95 | |
| AdrenalCortex | 9.8 | |
| Adrenalgland | 7.05 | |
| Amygdala | 8.25 | |
| Appendix | 13.7 | |
| AtrioventricularNode | 9.55 | |
| BDCA4+_DentriticCells | 9.95 | |
| Bonemarrow | 8.35 | |
| BronchialEpithelialCells | 7.85 | |
| CD105+_Endothelial | 54.9 | |
| CD14+_Monocytes | 9.55 | |
| CD19+_BCells(neg._sel.) | 8.45 | |
| CD33+_Myeloid | 15.1 | |
| CD34+ | 62.6 | |
| CD4+_Tcells | 12.3 | |
| CD56+_NKCells | 9.65 | |
| CD71+_EarlyErythroid | 8.4 | |
| CD8+_Tcells | 17.05 | |
| CardiacMyocytes | 19.9 | |
| Caudatenucleus | 7.35 | |
| Cerebellum | 6.85 | |
| CerebellumPeduncles | 9.45 | |
| CiliaryGanglion | 8.45 | |
| CingulateCortex | 8.55 | |
| Colorectaladenocarcinoma | 8.15 | |
| DorsalRootGanglion | 7.6 | |
| FetalThyroid | 8.3 | |
| Fetalbrain | 7.7 | |
| Fetalliver | 8.35 | |
| Fetallung | 6.05 | |
| GlobusPallidus | 7 | |
| Heart | 13.9 | |
| Hypothalamus | 8.15 | |
| Kidney | 7.5 | |
| Leukemia_chronicMyelogenousK-562 | 9.05 | |
| Leukemia_promyelocytic-HL-60 | 7.2 | |
| Leukemialymphoblastic(MOLT-4) | 7.35 | |
| Liver | 12.7 | |
| Lung | 8.75 | |
| Lymphnode | 6.55 | |
| Lymphoma_burkitts(Daudi) | 11.85 | |
| Lymphoma_burkitts(Raji) | 14 | |
| MedullaOblongata | 7.15 | |
| OccipitalLobe | 7.3 | |
| OlfactoryBulb | 6.15 | |
| Ovary | 6.95 | |
| Pancreas | 6.95 | |
| PancreaticIslet | 9.05 | |
| ParietalLobe | 9.45 | |
| Pituitary | 9.5 | |
| Placenta | 7.65 | |
| Pons | 8.15 | |
| PrefrontalCortex | 10 | |
| Prostate | 9.25 | |
| Salivarygland | 7.3 | |
| SkeletalMuscle | 14 | |
| Skin | 10.5 | |
| SmoothMuscle | 9.4 | |
| Spinalcord | 8.45 | |
| SubthalamicNucleus | 7.8 | |
| SuperiorCervicalGanglion | 12.35 | |
| TemporalLobe | 7.75 | |
| Testis | 6.9 | |
| TestisGermCell | 7.15 | |
| TestisIntersitial | 7.5 | |
| TestisLeydigCell | 9.3 | |
| TestisSeminiferousTubule | 6.9 | |
| Thalamus | 8.6 | |
| Thymus | 5.9 | |
| Thyroid | 9.75 | |
| Tongue | 9.25 | |
| Tonsil | 8.2 | |
| Trachea | 6.8 | |
| TrigeminalGanglion | 9.6 | |
| Uterus | 6.45 | |
| UterusCorpus | 8.4 | |
| WholeBlood | 9.5 | |
| Wholebrain | 5.9 | |
| colon | 8.2 | |
| pineal_day | 10.04 | |
| pineal_night | 10.08 | |
| retina | 10.05 | |
| small_intestine | 7.75 | |
- Probe name: A_23_P5611
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 8.11 ± 0.21 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 7.74 ± 0.17 | |
| Basal Part of Pons | 7.61 ± 0.27 | |
| Cerebellar Cortex | 7.96 ± 0.3 | |
| Cerebellar Nuclei | 7.61 ± 0.24 | |
| Claustrum | 8.21 ± 0.37 | |
| Epithalamus | 7.67 ± 0.29 | |
| Frontal Lobe | 7.69 ± 0.34 | |
| Globus Pallidus | 7.66 ± 0.23 | |
| Hypothalamus | 7.74 ± 0.28 | |
| Insula | 7.61 ± 0.25 | |
| Limbic Lobe | 7.9 ± 0.39 | |
| Mesencephalon | 7.84 ± 0.32 | |
| Myelencephalon | 7.78 ± 0.32 | |
| Occipital Lobe | 8.14 ± 0.31 | |
| Parietal Lobe | 7.8 ± 0.31 | |
| Pontine Tegmentum | 7.82 ± 0.36 | |
| Striatum | 7.88 ± 0.36 | |
| Subthalamus | 7.86 ± 0.1 | |
| Temporal Lobe | 7.74 ± 0.32 | |
| Thalamus | 7.66 ± 0.29 | |
| White Matter | 8.61 ± 0.34 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Rif1 | CB | Cerebellum | 63.27 | |
| 77.16 | | |||
| Rif1 | CTX | Cerebral cortex | 1.6 | |
| 1.28 | | |||
| Rif1 | HIP | Hippocampal region | 2.87 | |
| 2.39 | | |||
| Rif1 | HPF | Hippocampal formation | 2.62 | |
| 2.04 | | |||
| Rif1 | HY | Hypothalamus | 0.49 | |
| 0.55 | | |||
| Rif1 | LSX | Lateral septal complex | 2.59 | |
| 2.36 | | |||
| Rif1 | MB | Midbrain | 1.79 | |
| 1.65 | | |||
| Rif1 | MY | Medulla | 1.34 | |
| 1.36 | | |||
| Rif1 | OLF | Olfactory bulb | 2.29 | |
| 2.37 | | |||
| Rif1 | P | Pons | 1.46 | |
| 1.23 | | |||
| Rif1 | PAL | Pallidum | 0.4 | |
| 0.35 | | |||
| Rif1 | RHP | Retrohippocampal region | 2.24 | |
| 1.6 | | |||
| Rif1 | sAMY | Striatum-like amygdalar nuclei | 0.84 | |
| 0.54 | | |||
| Rif1 | STR | Striatum | 0.66 | |
| 0.66 | | |||
| Rif1 | STRd | Striatum dorsal region | 0.53 | |
| 0.63 | | |||
| Rif1 | STRv | Striatum ventral region | 0.27 | |
| 0.17 | | |||
| Rif1 | TH | Thalamus | 1.02 | |
| 0.85 | |
| Peptide Name | Peptide Lengh | Peptide Start | Peptide End | Peptide Sequence | Source |
|---|---|---|---|---|---|
| PAp00011486 | 17 | 299 | 315 | SLIDNFALNPDILCSAK | Peptide Atlas |