AutismKB 2.0

Annotation Detail for SETD5


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:SETD5 ( DKFZp686J18276,FLJ10707,KIAA1757 )
Gene Full Name: SET domain containing 5
Band: 3p25.3
Quick LinksEntrez ID:55209; OMIM: NA; Uniprot ID:SETD5_HUMAN; ENSEMBL ID: ENSG00000168137; HGNC ID: 25566
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body10 / 70761141
blastocyst7 / 62319112
fetus63 / 564012111
neonate0 / 310970 
infant0 / 236200 
juvenile7 / 55556125
adult187 / 193912196
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor4 / 9417842
cervical tumor3 / 3436687
chondrosarcoma7 / 8282384
colorectal tumor17 / 114246148
esophageal tumor0 / 172900 
gastrointestinal tumor8 / 11936967
germ cell tumor22 / 26384583
glioma11 / 106883102
head and neck tumor15 / 136302110
kidney tumor6 / 6895987
leukemia7 / 9584273
liver tumor6 / 9635962
lung tumor11 / 103127106
lymphoma2 / 7175527
non-neoplasia5 / 9725051
normal289 / 336030786
ovarian tumor2 / 7668226
pancreatic tumor5 / 10461647
primitive neuroectodermal tumor of the CNS4 / 12568031
prostate cancer18 / 102680175
retinoblastoma5 / 46356107
skin tumor1 / 1249498
soft tissue/muscle tissue tumor11 / 12519187
uterine tumor11 / 90257121
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland2 / 3319760
ascites1 / 4001524
bladder0 / 297570 
blood8 / 12347864
bone3 / 7165541
bone marrow3 / 4880161
brain64 / 110098958
cervix3 / 4817162
connective tissue5 / 14925533
ear2 / 16212123
embryonic tissue33 / 215722152
esophagus0 / 202090 
eye26 / 211054123
heart5 / 8962655
intestine23 / 23447298
kidney16 / 21177775
larynx1 / 2414541
liver16 / 20774377
lung18 / 33697453
lymph2 / 4427045
lymph node16 / 91610174
mammary gland14 / 15327191
mouth9 / 67052134
muscle13 / 107715120
nerve3 / 15768190
ovary3 / 10205129
pancreas15 / 21481269
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland3 / 16585180
placenta25 / 28082589
prostate25 / 189345132
salivary gland0 / 201550 
skin8 / 21057437
spleen4 / 5395274
stomach13 / 96619134
testis18 / 33044254
thymus3 / 8113136
thyroid9 / 47473189
tonsil0 / 169990 
trachea3 / 5241357
umbilical cord0 / 136800 
uterus20 / 23287885
vascular2 / 5178038
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 221806_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts426.1
Adipocyte76.25
AdrenalCortex191.8
Adrenalgland142.05
Amygdala70.25
Appendix70.45
AtrioventricularNode64.1
BDCA4+_DentriticCells209.75
Bonemarrow108.15
BronchialEpithelialCells88.35
CD105+_Endothelial82.85
CD14+_Monocytes138.5
CD19+_BCells(neg._sel.)234.25
CD33+_Myeloid235
CD34+368.05
CD4+_Tcells396.15
CD56+_NKCells255.8
CD71+_EarlyErythroid48.65
CD8+_Tcells357.75
CardiacMyocytes126.15
Caudatenucleus30.15
Cerebellum102
CerebellumPeduncles152
CiliaryGanglion54.3
CingulateCortex91.2
Colorectaladenocarcinoma62
DorsalRootGanglion53.75
FetalThyroid248.5
Fetalbrain125.7
Fetalliver61.1
Fetallung144
GlobusPallidus62.8
Heart68.2
Hypothalamus62.75
Kidney59.6
Leukemia_chronicMyelogenousK-562152.05
Leukemia_promyelocytic-HL-6079.4
Leukemialymphoblastic(MOLT-4)134.25
Liver93.4
Lung118.4
Lymphnode93.5
Lymphoma_burkitts(Daudi)178.6
Lymphoma_burkitts(Raji)235.95
MedullaOblongata80.15
OccipitalLobe83.45
OlfactoryBulb94
Ovary82.2
Pancreas130.15
PancreaticIslet111
ParietalLobe85.25
Pituitary168.55
Placenta183.35
Pons82.35
PrefrontalCortex423.35
Prostate165.7
Salivarygland93.25
SkeletalMuscle83.95
Skin98.15
SmoothMuscle193.55
Spinalcord41.6
SubthalamicNucleus101.15
SuperiorCervicalGanglion79.9
TemporalLobe69.45
Testis68.5
TestisGermCell238.15
TestisIntersitial138.95
TestisLeydigCell100.6
TestisSeminiferousTubule151.95
Thalamus75.7
Thymus165.9
Thyroid89.05
Tongue78.2
Tonsil168.15
Trachea119.4
TrigeminalGanglion70.05
Uterus192.85
UterusCorpus97.9
WholeBlood78.55
Wholebrain65.85
colon80.8
pineal_day210.98
pineal_night192.46
retina225.15
small_intestine82.15
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P92035
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.41 ± 0.39
Basal Forebrain5.23 ± 0.12
Basal Part of Pons5.37 ± 0.21
Cerebellar Cortex5.46 ± 0.36
Cerebellar Nuclei5.23 ± 0.37
Claustrum5.52 ± 0.47
Epithalamus4.85 ± 0.39
Frontal Lobe5.25 ± 0.37
Globus Pallidus4.84 ± 0.11
Hypothalamus4.99 ± 0.56
Insula5.18 ± 0.29
Limbic Lobe5.33 ± 0.34
Mesencephalon5.24 ± 0.4
Myelencephalon5.26 ± 0.36
Occipital Lobe5.22 ± 0.32
Parietal Lobe5.23 ± 0.35
Pontine Tegmentum5.1 ± 0.42
Striatum5.09 ± 0.35
Subthalamus5.25 ± 0.22
Temporal Lobe5.32 ± 0.34
Thalamus5.25 ± 0.31
White Matter4.77 ± 0.36
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Setd5CBCerebellum25.88
23.02
Setd5CTXCerebral cortex59.36
36.48
Setd5HIPHippocampal region72.21
61.91
Setd5HPFHippocampal formation69.13
53.57
Setd5HYHypothalamus36.95
22.78
Setd5LSXLateral septal complex32.08
18.39
Setd5MBMidbrain28.9
19.91
Setd5MYMedulla37.05
31.12
Setd5OLFOlfactory bulb71.52
41.79
Setd5PPons30.76
24.41
Setd5PALPallidum24.57
16.68
Setd5RHPRetrohippocampal region63.15
39.98
Setd5sAMYStriatum-like amygdalar nuclei43.89
22.85
Setd5STRStriatum22.12
12.24
Setd5STRdStriatum dorsal region16
9.12
Setd5STRvStriatum ventral region25.37
12.83
Setd5THThalamus38.5
26.17
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved