AutismKB 2.0

Annotation Detail for LEPREL1


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Basic Information Top
Gene Symbol:LEPREL1 ( FLJ10718,MLAT4,P3H2 )
Gene Full Name: leprecan-like 1
Band: 3q28
Quick LinksEntrez ID:55214; OMIM: 610341; Uniprot ID:P3H2_HUMAN; ENSEMBL ID: ENSG00000090530; HGNC ID:
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body6 / 7076184
blastocyst5 / 6231980
fetus4 / 5640127
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult66 / 193912134
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor2 / 12794156
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma6 / 8282372
colorectal tumor3 / 11424626
esophageal tumor0 / 172900 
gastrointestinal tumor9 / 11936975
germ cell tumor15 / 26384556
glioma3 / 10688328
head and neck tumor3 / 13630222
kidney tumor8 / 68959116
leukemia0 / 958420 
liver tumor3 / 9635931
lung tumor8 / 10312777
lymphoma0 / 717550 
non-neoplasia2 / 9725020
normal94 / 336030727
ovarian tumor3 / 7668239
pancreatic tumor6 / 10461657
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer2 / 10268019
retinoblastoma0 / 463560 
skin tumor2 / 12494916
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland4 / 33197120
ascites0 / 400150 
bladder1 / 2975733
blood0 / 1234780 
bone5 / 7165569
bone marrow0 / 488010 
brain7 / 11009896
cervix0 / 481710 
connective tissue3 / 14925520
ear0 / 162120 
embryonic tissue11 / 21572250
esophagus0 / 202090 
eye8 / 21105437
heart1 / 8962611
intestine17 / 23447272
kidney27 / 211777127
larynx0 / 241450 
liver3 / 20774314
lung14 / 33697441
lymph0 / 442700 
lymph node0 / 916100 
mammary gland1 / 1532716
mouth3 / 6705244
muscle1 / 1077159
nerve0 / 157680 
ovary4 / 10205139
pancreas6 / 21481227
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta3 / 28082510
prostate19 / 189345100
salivary gland0 / 201550 
skin7 / 21057433
spleen4 / 5395274
stomach1 / 9661910
testis11 / 33044233
thymus1 / 8113112
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus14 / 23287860
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 218717_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts318.5
Adipocyte4
AdrenalCortex17.85
Adrenalgland4.15
Amygdala4.1
Appendix4
AtrioventricularNode3.05
BDCA4+_DentriticCells149.9
Bonemarrow4.05
BronchialEpithelialCells4
CD105+_Endothelial4.1
CD14+_Monocytes4.3
CD19+_BCells(neg._sel.)4.2
CD33+_Myeloid5.15
CD34+5.15
CD4+_Tcells4.35
CD56+_NKCells4.8
CD71+_EarlyErythroid3.7
CD8+_Tcells3.85
CardiacMyocytes5.15
Caudatenucleus3.6
Cerebellum3.25
CerebellumPeduncles4.55
CiliaryGanglion2.95
CingulateCortex4.1
Colorectaladenocarcinoma4
DorsalRootGanglion4.55
FetalThyroid3.9
Fetalbrain4.05
Fetalliver3.45
Fetallung5.8
GlobusPallidus2.95
Heart5.1
Hypothalamus4.4
Kidney5.05
Leukemia_chronicMyelogenousK-5623.65
Leukemia_promyelocytic-HL-603.55
Leukemialymphoblastic(MOLT-4)3.25
Liver5.3
Lung17.15
Lymphnode3.5
Lymphoma_burkitts(Daudi)5.15
Lymphoma_burkitts(Raji)5.6
MedullaOblongata3.65
OccipitalLobe3.55
OlfactoryBulb7.45
Ovary2.65
Pancreas3.2
PancreaticIslet4.25
ParietalLobe4.15
Pituitary4.95
Placenta8.8
Pons3.8
PrefrontalCortex4.9
Prostate58.3
Salivarygland3.2
SkeletalMuscle6.05
Skin7.1
SmoothMuscle4.55
Spinalcord5.8
SubthalamicNucleus3.65
SuperiorCervicalGanglion4.55
TemporalLobe3.65
Testis3.6
TestisGermCell3.35
TestisIntersitial3.4
TestisLeydigCell4.75
TestisSeminiferousTubule3.45
Thalamus4
Thymus3.15
Thyroid5
Tongue3.95
Tonsil3.9
Trachea3.4
TrigeminalGanglion4.05
Uterus3.3
UterusCorpus3.6
WholeBlood4.4
Wholebrain3.35
colon4.05
pineal_day5.06
pineal_night5.12
retina5.925
small_intestine3.85
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P69179
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.72 ± 0.24
Basal Forebrain7.32 ± 0.23
Basal Part of Pons7.55 ± 0.27
Cerebellar Cortex6.91 ± 0.36
Cerebellar Nuclei7.51 ± 0.26
Claustrum8.21 ± 0.35
Epithalamus8.45 ± 0.53
Frontal Lobe7.55 ± 0.44
Globus Pallidus7.93 ± 0.37
Hypothalamus8.21 ± 0.33
Insula7.8 ± 0.35
Limbic Lobe7.47 ± 0.61
Mesencephalon7.59 ± 0.43
Myelencephalon7.5 ± 0.55
Occipital Lobe7.26 ± 0.38
Parietal Lobe7.51 ± 0.36
Pontine Tegmentum7.44 ± 0.5
Striatum7.07 ± 0.75
Subthalamus6.98 ± 0.1
Temporal Lobe7.57 ± 0.36
Thalamus7.16 ± 0.47
White Matter9.15 ± 0.47
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Leprel1CBCerebellum1.34
1.54
Leprel1CTXCerebral cortex3.54
4.05
Leprel1HIPHippocampal region3.67
3.59
Leprel1HPFHippocampal formation2.49
2.34
Leprel1HYHypothalamus0.12
0.12
Leprel1LSXLateral septal complex0.07
0.03
Leprel1MBMidbrain0.86
0.85
Leprel1MYMedulla2.14
2.12
Leprel1OLFOlfactory bulb4.37
3.5
Leprel1PPons0.96
1.15
Leprel1PALPallidum0.2
0.14
Leprel1RHPRetrohippocampal region0.43
0.53
Leprel1sAMYStriatum-like amygdalar nuclei0.12
0.19
Leprel1STRStriatum0.39
0.38
Leprel1STRdStriatum dorsal region0.55
0.57
Leprel1STRvStriatum ventral region0.29
0.17
Leprel1THThalamus0.87
0.77
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00505830 20 92 111 HPLPPPPPGEGPGAELPLFR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018