AutismKB 2.0

Annotation Detail for NAT10


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Basic Information Top
Gene Symbol:NAT10 ( ALP,DKFZp434C116,FLJ10774,FLJ12179,FLJ23850,KIAA1709,NET43 )
Gene Full Name: N-acetyltransferase 10 (GCN5-related)
Band: 11p13
Quick LinksEntrez ID:55226; OMIM: 609221; Uniprot ID:NAT10_HUMAN; ENSEMBL ID: ENSG00000135372; HGNC ID: 29830
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body5 / 7076170
blastocyst10 / 62319160
fetus54 / 56401295
neonate7 / 31097225
infant1 / 2362042
juvenile9 / 55556161
adult175 / 193912190
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor2 / 12794156
bladder carcinoma2 / 17475114
breast (mammary gland) tumor6 / 9417863
cervical tumor2 / 3436658
chondrosarcoma5 / 8282360
colorectal tumor20 / 114246175
esophageal tumor6 / 17290347
gastrointestinal tumor16 / 119369134
germ cell tumor42 / 263845159
glioma5 / 10688346
head and neck tumor43 / 136302315
kidney tumor2 / 6895929
leukemia7 / 9584273
liver tumor9 / 9635993
lung tumor9 / 10312787
lymphoma4 / 7175555
non-neoplasia8 / 9725082
normal269 / 336030780
ovarian tumor5 / 7668265
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS8 / 12568063
prostate cancer14 / 102680136
retinoblastoma6 / 46356129
skin tumor7 / 12494956
soft tissue/muscle tissue tumor8 / 12519163
uterine tumor7 / 9025777
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland4 / 33197120
ascites11 / 40015274
bladder1 / 2975733
blood11 / 12347889
bone6 / 7165583
bone marrow12 / 48801245
brain151 / 1100989137
cervix8 / 48171166
connective tissue14 / 14925593
ear1 / 1621261
embryonic tissue17 / 21572278
esophagus6 / 20209296
eye10 / 21105447
heart4 / 8962644
intestine30 / 234472127
kidney14 / 21177766
larynx1 / 2414541
liver11 / 20774352
lung24 / 33697471
lymph2 / 4427045
lymph node3 / 9161032
mammary gland12 / 15327178
mouth29 / 67052432
muscle7 / 10771564
nerve0 / 157680 
ovary8 / 10205178
pancreas2 / 2148129
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta12 / 28082542
prostate17 / 18934589
salivary gland4 / 20155198
skin10 / 21057447
spleen7 / 53952129
stomach4 / 9661941
testis48 / 330442145
thymus11 / 81131135
thyroid12 / 47473252
tonsil0 / 169990 
trachea9 / 52413171
umbilical cord8 / 13680584
uterus23 / 23287898
vascular2 / 5178038
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 217884_at
Cell line Expression level Expression bar
721_B_lymphoblasts366.6
Adipocyte31.55
AdrenalCortex35
Adrenalgland29.65
Amygdala33.95
Appendix10.95
AtrioventricularNode11.6
BDCA4+_DentriticCells92.95
Bonemarrow36.45
BronchialEpithelialCells63.45
CD105+_Endothelial136.4
CD14+_Monocytes52.45
CD19+_BCells(neg._sel.)64.85
CD33+_Myeloid51.9
CD34+331.25
CD4+_Tcells125.1
CD56+_NKCells57.6
CD71+_EarlyErythroid31.9
CD8+_Tcells122.25
CardiacMyocytes21
Caudatenucleus21.9
Cerebellum29.3
CerebellumPeduncles35.2
CiliaryGanglion9.15
CingulateCortex21.9
Colorectaladenocarcinoma160.05
DorsalRootGanglion13.1
FetalThyroid27.4
Fetalbrain18
Fetalliver24.55
Fetallung28.25
GlobusPallidus10.55
Heart22.25
Hypothalamus42.05
Kidney14.6
Leukemia_chronicMyelogenousK-56272.6
Leukemia_promyelocytic-HL-60138.25
Leukemialymphoblastic(MOLT-4)122.45
Liver43.2
Lung45.85
Lymphnode36.95
Lymphoma_burkitts(Daudi)277.45
Lymphoma_burkitts(Raji)79.3
MedullaOblongata29.7
OccipitalLobe26.9
OlfactoryBulb27.35
Ovary25.6
Pancreas19.7
PancreaticIslet34.6
ParietalLobe25.9
Pituitary32.85
Placenta33.95
Pons21.1
PrefrontalCortex57.6
Prostate54.15
Salivarygland11
SkeletalMuscle28.1
Skin16.9
SmoothMuscle32.3
Spinalcord26.8
SubthalamicNucleus23.05
SuperiorCervicalGanglion44.95
TemporalLobe15.75
Testis72.05
TestisGermCell45.4
TestisIntersitial36.5
TestisLeydigCell76.35
TestisSeminiferousTubule50.05
Thalamus28.2
Thymus51.2
Thyroid36.6
Tongue36
Tonsil50.25
Trachea22.55
TrigeminalGanglion15.35
Uterus43.85
UterusCorpus21.35
WholeBlood31.7
Wholebrain32.2
colon17.25
pineal_day91.42
pineal_night67.3
retina54.15
small_intestine26.15
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P87329
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.58 ± 0.5
Basal Forebrain5.93 ± 0.23
Basal Part of Pons6.2 ± 0.27
Cerebellar Cortex6.02 ± 0.28
Cerebellar Nuclei6.1 ± 0.35
Claustrum5.51 ± 0.51
Epithalamus5.94 ± 0.3
Frontal Lobe6.03 ± 0.37
Globus Pallidus5.69 ± 0.32
Hypothalamus6.13 ± 0.31
Insula5.99 ± 0.27
Limbic Lobe5.82 ± 0.44
Mesencephalon5.88 ± 0.37
Myelencephalon5.95 ± 0.44
Occipital Lobe5.74 ± 0.35
Parietal Lobe5.96 ± 0.43
Pontine Tegmentum5.84 ± 0.48
Striatum5.61 ± 0.4
Subthalamus5.56 ± 0.71
Temporal Lobe6.06 ± 0.37
Thalamus5.95 ± 0.4
White Matter5.33 ± 0.52
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Nat10CBCerebellum19.08
19.29
Nat10CTXCerebral cortex23.58
14.83
Nat10HIPHippocampal region15.53
14.51
Nat10HPFHippocampal formation12.52
10.84
Nat10HYHypothalamus7.36
4.84
Nat10LSXLateral septal complex13.58
8.32
Nat10MBMidbrain8.1
6.2
Nat10MYMedulla22.28
19.89
Nat10OLFOlfactory bulb30.79
21.07
Nat10PPons11.69
10.37
Nat10PALPallidum10.72
7.87
Nat10RHPRetrohippocampal region7.54
5.84
Nat10sAMYStriatum-like amygdalar nuclei13.02
7.82
Nat10STRStriatum14.31
9.22
Nat10STRdStriatum dorsal region10.65
7.14
Nat10STRvStriatum ventral region24.91
14.81
Nat10THThalamus14.86
10.25
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
NAT10_HUMAN_883 15 883 897 EIELPSGQLMGLFNR PRIDE
PAp00065941 13 811 823 EELEALFLPYDLK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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