AutismKB 2.0

Annotation Detail for LRRC1


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:LRRC1 ( FLJ10775,FLJ11834,LANO,dJ523E19.1 )
Gene Full Name: leucine rich repeat containing 1
Band: 6p12.1
Quick LinksEntrez ID:55227; OMIM: 608195; Uniprot ID:LRRC1_HUMAN; ENSEMBL ID: ENSG00000137269; HGNC ID: 14307
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body5 / 7076170
blastocyst1 / 6231916
fetus5 / 5640128
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult54 / 193912127
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma2 / 17475114
breast (mammary gland) tumor5 / 9417853
cervical tumor1 / 3436629
chondrosarcoma3 / 8282336
colorectal tumor3 / 11424626
esophageal tumor0 / 172900 
gastrointestinal tumor2 / 11936916
germ cell tumor10 / 26384537
glioma1 / 1068839
head and neck tumor2 / 13630214
kidney tumor1 / 6895914
leukemia3 / 9584231
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia1 / 9725010
normal74 / 336030722
ovarian tumor0 / 766820 
pancreatic tumor4 / 10461638
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor4 / 9025744
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites2 / 4001549
bladder2 / 2975767
blood2 / 12347816
bone4 / 7165555
bone marrow1 / 4880120
brain17 / 110098915
cervix1 / 4817120
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue8 / 21572237
esophagus0 / 202090 
eye3 / 21105414
heart0 / 896260 
intestine5 / 23447221
kidney1 / 2117774
larynx0 / 241450 
liver0 / 2077430 
lung7 / 33697420
lymph0 / 442700 
lymph node2 / 9161021
mammary gland6 / 15327139
mouth1 / 6705214
muscle5 / 10771546
nerve1 / 1576863
ovary0 / 1020510 
pancreas7 / 21481232
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta21 / 28082574
prostate0 / 1893450 
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach0 / 966190 
testis10 / 33044230
thymus2 / 8113124
thyroid3 / 4747363
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus4 / 23287817
vascular4 / 5178077
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 218816_at
Cell line Expression level Expression bar
721_B_lymphoblasts13.05
Adipocyte7.65
AdrenalCortex9.4
Adrenalgland7
Amygdala8.35
Appendix12.15
AtrioventricularNode8.5
BDCA4+_DentriticCells8.05
Bonemarrow8.6
BronchialEpithelialCells17.55
CD105+_Endothelial7.75
CD14+_Monocytes8.7
CD19+_BCells(neg._sel.)9
CD33+_Myeloid9.6
CD34+10.15
CD4+_Tcells8.55
CD56+_NKCells8.75
CD71+_EarlyErythroid7.55
CD8+_Tcells7.2
CardiacMyocytes12.85
Caudatenucleus7.3
Cerebellum6.55
CerebellumPeduncles9.4
CiliaryGanglion8.15
CingulateCortex8.45
Colorectaladenocarcinoma8.7
DorsalRootGanglion7.85
FetalThyroid11.4
Fetalbrain7.7
Fetalliver7.4
Fetallung6.35
GlobusPallidus6.2
Heart12.55
Hypothalamus10.8
Kidney7
Leukemia_chronicMyelogenousK-5627.25
Leukemia_promyelocytic-HL-607.1
Leukemialymphoblastic(MOLT-4)8.6
Liver12.05
Lung8.9
Lymphnode6.75
Lymphoma_burkitts(Daudi)10.6
Lymphoma_burkitts(Raji)12.3
MedullaOblongata7.25
OccipitalLobe7.15
OlfactoryBulb6.65
Ovary6.15
Pancreas7.15
PancreaticIslet9.1
ParietalLobe9.15
Pituitary9.45
Placenta126.1
Pons7.9
PrefrontalCortex10.45
Prostate13.55
Salivarygland9.25
SkeletalMuscle12.65
Skin9.05
SmoothMuscle8.85
Spinalcord9
SubthalamicNucleus7.6
SuperiorCervicalGanglion13.05
TemporalLobe7.65
Testis6.85
TestisGermCell9.7
TestisIntersitial6.9
TestisLeydigCell8.5
TestisSeminiferousTubule7.1
Thalamus8.4
Thymus6.6
Thyroid12.05
Tongue9.5
Tonsil10.2
Trachea9
TrigeminalGanglion10.45
Uterus8.35
UterusCorpus7.95
WholeBlood8.45
Wholebrain6.85
colon140.25
pineal_day9.6
pineal_night9.58
retina10.275
small_intestine49.4
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_5289_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.58 ± 0.81
Basal Forebrain5.42 ± 0.48
Basal Part of Pons4.15 ± 0.56
Cerebellar Cortex3.9 ± 0.45
Cerebellar Nuclei4.79 ± 0.65
Claustrum4.82 ± 0.84
Epithalamus4.74 ± 0.7
Frontal Lobe4.12 ± 0.81
Globus Pallidus5.87 ± 0.31
Hypothalamus4.49 ± 0.59
Insula3.65 ± 0.88
Limbic Lobe4.06 ± 0.92
Mesencephalon4.57 ± 0.76
Myelencephalon4.52 ± 0.7
Occipital Lobe4.71 ± 0.76
Parietal Lobe4.3 ± 0.74
Pontine Tegmentum4.56 ± 0.74
Striatum5.52 ± 0.54
Subthalamus4.27 ± 0.63
Temporal Lobe4.08 ± 0.66
Thalamus4.68 ± 0.45
White Matter6.72 ± 0.48
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Lrrc1CBCerebellum2.1
2.41
Lrrc1CTXCerebral cortex0.52
0.48
Lrrc1HIPHippocampal region0.96
1.01
Lrrc1HPFHippocampal formation0.85
0.88
Lrrc1HYHypothalamus2.16
2.75
Lrrc1LSXLateral septal complex1.61
1.74
Lrrc1MBMidbrain0.77
0.66
Lrrc1MYMedulla1.28
1.64
Lrrc1OLFOlfactory bulb5.99
5.39
Lrrc1PPons1.17
1.29
Lrrc1PALPallidum1.87
1.64
Lrrc1RHPRetrohippocampal region0.73
0.75
Lrrc1sAMYStriatum-like amygdalar nuclei2.87
2
Lrrc1STRStriatum3.62
2.85
Lrrc1STRdStriatum dorsal region3.18
2.54
Lrrc1STRvStriatum ventral region6.32
4.66
Lrrc1THThalamus0.54
0.46
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00000988 19 432 450 CGALENLVNDVSDEAWNER Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved