AutismKB 2.0

Annotation Detail for MOBKL1B


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Basic Information Top
Gene Symbol:MOBKL1B ( C2orf6,FLJ10788,FLJ11595,MATS1,MOB1,MOBK1B,Mob4B )
Gene Full Name: MOB1, Mps One Binder kinase activator-like 1B (yeast)
Band: 2p13.1
Quick LinksEntrez ID:55233; OMIM: 609281; Uniprot ID:MOL1B_HUMAN; ENSEMBL ID: ENSG00000114978; HGNC ID:
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 201299_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts34.95
Adipocyte7
AdrenalCortex7.7
Adrenalgland6.3
Amygdala6.65
Appendix10.8
AtrioventricularNode8.1
BDCA4+_DentriticCells32.75
Bonemarrow7.3
BronchialEpithelialCells7.5
CD105+_Endothelial7.2
CD14+_Monocytes11.8
CD19+_BCells(neg._sel.)25.2
CD33+_Myeloid51.85
CD34+10.45
CD4+_Tcells8.65
CD56+_NKCells38
CD71+_EarlyErythroid6.7
CD8+_Tcells17.5
CardiacMyocytes13.35
Caudatenucleus6.25
Cerebellum5.7
CerebellumPeduncles8.15
CiliaryGanglion8.4
CingulateCortex7.5
Colorectaladenocarcinoma7.05
DorsalRootGanglion6.45
FetalThyroid7.1
Fetalbrain7
Fetalliver6.25
Fetallung5.3
GlobusPallidus5.5
Heart12.55
Hypothalamus7.05
Kidney6.45
Leukemia_chronicMyelogenousK-5626.1
Leukemia_promyelocytic-HL-606.05
Leukemialymphoblastic(MOLT-4)5.5
Liver10.6
Lung7.4
Lymphnode5.75
Lymphoma_burkitts(Daudi)8.95
Lymphoma_burkitts(Raji)10.2
MedullaOblongata6.25
OccipitalLobe6.35
OlfactoryBulb5.4
Ovary4.7
Pancreas6.05
PancreaticIslet7.4
ParietalLobe8.1
Pituitary8.15
Placenta6.5
Pons6.95
PrefrontalCortex8.45
Prostate8
Salivarygland5.75
SkeletalMuscle10.8
Skin6.2
SmoothMuscle8
Spinalcord7.5
SubthalamicNucleus6.65
SuperiorCervicalGanglion10.55
TemporalLobe6.55
Testis6.05
TestisGermCell5.55
TestisIntersitial5.8
TestisLeydigCell7.05
TestisSeminiferousTubule5.85
Thalamus7.25
Thymus5.6
Thyroid8.35
Tongue7.1
Tonsil7.1
Trachea5.9
TrigeminalGanglion9.25
Uterus5.7
UterusCorpus7.35
WholeBlood9.4
Wholebrain5.35
colon13
pineal_day8.1
pineal_night8.2
retina8.5
small_intestine6.85
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_1805_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala8.05 ± 0.25
Basal Forebrain8.04 ± 0.16
Basal Part of Pons7.77 ± 0.29
Cerebellar Cortex7.84 ± 0.34
Cerebellar Nuclei8.34 ± 0.3
Claustrum7.78 ± 0.31
Epithalamus8.58 ± 0.32
Frontal Lobe7.78 ± 0.41
Globus Pallidus8.82 ± 0.19
Hypothalamus8.09 ± 0.48
Insula7.66 ± 0.38
Limbic Lobe7.75 ± 0.36
Mesencephalon8.03 ± 0.37
Myelencephalon7.89 ± 0.34
Occipital Lobe7.9 ± 0.28
Parietal Lobe7.91 ± 0.35
Pontine Tegmentum7.88 ± 0.36
Striatum8 ± 0.43
Subthalamus8.05 ± 0.15
Temporal Lobe7.79 ± 0.31
Thalamus7.9 ± 0.25
White Matter8.67 ± 0.4
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Mobk1bCBCerebellum0.4
1.14
Mobk1bCTXCerebral cortex2.41
2.45
Mobk1bHIPHippocampal region0.75
0.72
Mobk1bHPFHippocampal formation0.66
0.55
Mobk1bHYHypothalamus0.11
0.21
Mobk1bLSXLateral septal complex0.62
0.72
Mobk1bMBMidbrain0.23
0.51
Mobk1bMYMedulla0.06
0.1
Mobk1bOLFOlfactory bulb3.09
3.31
Mobk1bPPons0.03
0.06
Mobk1bPALPallidum0.68
0.61
Mobk1bRHPRetrohippocampal region0.54
0.35
Mobk1bsAMYStriatum-like amygdalar nuclei2.16
1.8
Mobk1bSTRStriatum0.64
0.66
Mobk1bSTRdStriatum dorsal region0.42
0.41
Mobk1bSTRvStriatum ventral region0.69
0.38
Mobk1bTHThalamus0.47
0.52
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
MOL1B_HUMAN_0 0 0 0 ELAPLQELIEK PRIDE
MOL1B_HUMAN_0 0 0 0 HAEATLGSGNLR PRIDE
MOL1B_HUMAN_0 0 0 0 YEYHWADGTNIK PRIDE
MOL1B_HUMAN_157 27 157 183 VYAHIYHQHFDSVMQLQEEAHLNTSFK PRIDE
MOL1B_HUMAN_16 14 16 29 KNIPEGSHQYELLK PRIDE
MOL1B_HUMAN_199 11 199 209 ELAPLQELIEK PRIDE
MOL1B_HUMAN_2 7 2 8 SFLFSSR PRIDE
MOL1B_HUMAN_92 12 92 103 YEYHWADGTNIK PRIDE
PAp00382825 12 31 42 HAEATLGSGNLR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018