AutismKB 2.0

Annotation Detail for CCDC25


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Basic Information Top
Gene Symbol:CCDC25 ( FLJ10853 )
Gene Full Name: coiled-coil domain containing 25
Band: 8p21.1
Quick LinksEntrez ID:55246; OMIM: NA; Uniprot ID:CCD25_HUMAN; ENSEMBL ID: ENSG00000147419; HGNC ID: 25591
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body6 / 7076184
blastocyst6 / 6231996
fetus43 / 56401276
neonate3 / 3109796
infant2 / 2362084
juvenile5 / 5555689
adult137 / 193912170
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor13 / 94178138
cervical tumor3 / 3436687
chondrosarcoma14 / 82823169
colorectal tumor9 / 11424678
esophageal tumor0 / 172900 
gastrointestinal tumor8 / 11936967
germ cell tumor12 / 26384545
glioma4 / 10688337
head and neck tumor3 / 13630222
kidney tumor5 / 6895972
leukemia3 / 9584231
liver tumor9 / 9635993
lung tumor0 / 1031270 
lymphoma3 / 7175541
non-neoplasia4 / 9725041
normal247 / 336030773
ovarian tumor3 / 7668239
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS9 / 12568071
prostate cancer6 / 10268058
retinoblastoma5 / 46356107
skin tumor6 / 12494948
soft tissue/muscle tissue tumor7 / 12519155
uterine tumor8 / 9025788
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland2 / 3319760
ascites2 / 4001549
bladder1 / 2975733
blood5 / 12347840
bone11 / 71655153
bone marrow0 / 488010 
brain74 / 110098967
cervix3 / 4817162
connective tissue6 / 14925540
ear0 / 162120 
embryonic tissue16 / 21572274
esophagus0 / 202090 
eye16 / 21105475
heart5 / 8962655
intestine18 / 23447276
kidney16 / 21177775
larynx0 / 241450 
liver14 / 20774367
lung21 / 33697462
lymph1 / 4427022
lymph node6 / 9161065
mammary gland14 / 15327191
mouth1 / 6705214
muscle8 / 10771574
nerve0 / 157680 
ovary4 / 10205139
pancreas8 / 21481237
parathyroid4 / 20539194
pharynx4 / 4132896
pituitary gland0 / 165850 
placenta8 / 28082528
prostate16 / 18934584
salivary gland0 / 201550 
skin17 / 21057480
spleen0 / 539520 
stomach9 / 9661993
testis35 / 330442105
thymus4 / 8113149
thyroid2 / 4747342
tonsil0 / 169990 
trachea7 / 52413133
umbilical cord1 / 1368073
uterus33 / 232878141
vascular4 / 5178077
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 218125_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts44.45
Adipocyte35.9
AdrenalCortex38.35
Adrenalgland30.4
Amygdala44.5
Appendix36.2
AtrioventricularNode27.1
BDCA4+_DentriticCells26.55
Bonemarrow35
BronchialEpithelialCells35.6
CD105+_Endothelial36.2
CD14+_Monocytes30.2
CD19+_BCells(neg._sel.)38.85
CD33+_Myeloid14.2
CD34+44.85
CD4+_Tcells38.85
CD56+_NKCells41.9
CD71+_EarlyErythroid33.75
CD8+_Tcells35.15
CardiacMyocytes44.95
Caudatenucleus39
Cerebellum29.05
CerebellumPeduncles41.35
CiliaryGanglion25.25
CingulateCortex43.05
Colorectaladenocarcinoma36.15
DorsalRootGanglion27.3
FetalThyroid40.3
Fetalbrain35.45
Fetalliver31.2
Fetallung29.7
GlobusPallidus26.95
Heart45.75
Hypothalamus51.8
Kidney29.2
Leukemia_chronicMyelogenousK-56232.75
Leukemia_promyelocytic-HL-6038.8
Leukemialymphoblastic(MOLT-4)31.35
Liver46.95
Lung38.85
Lymphnode31.25
Lymphoma_burkitts(Daudi)46.05
Lymphoma_burkitts(Raji)50.15
MedullaOblongata48.3
OccipitalLobe42.6
OlfactoryBulb34.85
Ovary23.85
Pancreas29.1
PancreaticIslet38.45
ParietalLobe47.55
Pituitary42.2
Placenta29.65
Pons36.15
PrefrontalCortex64.85
Prostate40.7
Salivarygland29.2
SkeletalMuscle40.9
Skin27.7
SmoothMuscle40.8
Spinalcord59.75
SubthalamicNucleus40.15
SuperiorCervicalGanglion40.35
TemporalLobe33.2
Testis30.55
TestisGermCell30
TestisIntersitial30
TestisLeydigCell35.55
TestisSeminiferousTubule31
Thalamus47.85
Thymus28.2
Thyroid44.95
Tongue39.2
Tonsil35.15
Trachea30.2
TrigeminalGanglion35.35
Uterus29.8
UterusCorpus32
WholeBlood27.15
Wholebrain30.3
colon36.5
pineal_day53.1
pineal_night45.54
retina43.95
small_intestine36
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P158142
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala9.29 ± 0.29
Basal Forebrain9.35 ± 0.15
Basal Part of Pons9.68 ± 0.13
Cerebellar Cortex9.23 ± 0.19
Cerebellar Nuclei9.9 ± 0.23
Claustrum9.58 ± 0.15
Epithalamus9.65 ± 0.16
Frontal Lobe9.67 ± 0.35
Globus Pallidus10.05 ± 0.2
Hypothalamus9.52 ± 0.16
Insula9.36 ± 0.18
Limbic Lobe9.44 ± 0.43
Mesencephalon9.54 ± 0.3
Myelencephalon9.5 ± 0.31
Occipital Lobe9.46 ± 0.29
Parietal Lobe9.71 ± 0.25
Pontine Tegmentum9.55 ± 0.35
Striatum9.44 ± 0.28
Subthalamus9.9 ± 0.23
Temporal Lobe9.46 ± 0.27
Thalamus9.58 ± 0.21
White Matter9.6 ± 0.11
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Ccdc25CBCerebellum4.23
4.69
Ccdc25CTXCerebral cortex5.94
2.45
Ccdc25HIPHippocampal region3.24
2.47
Ccdc25HPFHippocampal formation3.3
2.14
Ccdc25HYHypothalamus0.69
0.47
Ccdc25LSXLateral septal complex0.24
0.19
Ccdc25MBMidbrain1.71
1.21
Ccdc25MYMedulla5.64
3.94
Ccdc25OLFOlfactory bulb4.62
2.35
Ccdc25PPons6.97
5.62
Ccdc25PALPallidum1.99
0.88
Ccdc25RHPRetrohippocampal region3.51
1.7
Ccdc25sAMYStriatum-like amygdalar nuclei4.07
1.55
Ccdc25STRStriatum1.72
0.73
Ccdc25STRdStriatum dorsal region1.18
0.53
Ccdc25STRvStriatum ventral region2.65
1.04
Ccdc25THThalamus1.21
0.74
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00002522 11 141 151 FPDLAAEKECR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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