AutismKB 2.0

Annotation Detail for PPP2R5C


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Basic Information Top
Gene Symbol:PPP2R5C ( B56G,MGC23064,PR61G )
Gene Full Name: protein phosphatase 2, regulatory subunit B', gamma
Band: 14q32.31
Quick LinksEntrez ID:5527; OMIM: 601645; Uniprot ID:2A5G_HUMAN; ENSEMBL ID: ENSG00000078304; HGNC ID: 9311
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body11 / 70761155
blastocyst5 / 6231980
fetus90 / 564012159
neonate5 / 31097160
infant0 / 236200 
juvenile10 / 55556179
adult183 / 193912194
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor3 / 12794234
bladder carcinoma3 / 17475171
breast (mammary gland) tumor7 / 9417874
cervical tumor2 / 3436658
chondrosarcoma10 / 82823120
colorectal tumor8 / 11424670
esophageal tumor0 / 172900 
gastrointestinal tumor12 / 119369100
germ cell tumor65 / 263845246
glioma16 / 106883149
head and neck tumor8 / 13630258
kidney tumor10 / 68959145
leukemia13 / 95842135
liver tumor11 / 96359114
lung tumor14 / 103127135
lymphoma13 / 71755181
non-neoplasia12 / 97250123
normal436 / 3360307129
ovarian tumor8 / 76682104
pancreatic tumor4 / 10461638
primitive neuroectodermal tumor of the CNS14 / 125680111
prostate cancer6 / 10268058
retinoblastoma3 / 4635664
skin tumor9 / 12494972
soft tissue/muscle tissue tumor14 / 125191111
uterine tumor9 / 9025799
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland5 / 33197150
ascites2 / 4001549
bladder4 / 29757134
blood15 / 123478121
bone6 / 7165583
bone marrow11 / 48801225
brain128 / 1100989116
cervix2 / 4817141
connective tissue16 / 149255107
ear4 / 16212246
embryonic tissue27 / 215722125
esophagus1 / 2020949
eye17 / 21105480
heart12 / 89626133
intestine18 / 23447276
kidney20 / 21177794
larynx1 / 2414541
liver17 / 20774381
lung37 / 336974109
lymph3 / 4427067
lymph node38 / 91610414
mammary gland16 / 153271104
mouth5 / 6705274
muscle8 / 10771574
nerve4 / 15768253
ovary9 / 10205188
pancreas15 / 21481269
parathyroid4 / 20539194
pharynx3 / 4132872
pituitary gland2 / 16585120
placenta28 / 28082599
prostate14 / 18934573
salivary gland2 / 2015599
skin29 / 210574137
spleen9 / 53952166
stomach14 / 96619144
testis72 / 330442217
thymus20 / 81131246
thyroid2 / 4747342
tonsil1 / 1699958
trachea22 / 52413419
umbilical cord1 / 1368073
uterus39 / 232878167
vascular8 / 51780154
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 201877_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts74.8
Adipocyte12.85
AdrenalCortex7.4
Adrenalgland10
Amygdala227.35
Appendix8.65
AtrioventricularNode9.05
BDCA4+_DentriticCells189.4
Bonemarrow7
BronchialEpithelialCells30.15
CD105+_Endothelial39.35
CD14+_Monocytes89.75
CD19+_BCells(neg._sel.)147.35
CD33+_Myeloid66.3
CD34+32.9
CD4+_Tcells306.7
CD56+_NKCells564.25
CD71+_EarlyErythroid58.35
CD8+_Tcells419.75
CardiacMyocytes10.9
Caudatenucleus29
Cerebellum5.65
CerebellumPeduncles7.7
CiliaryGanglion5.2
CingulateCortex25.05
Colorectaladenocarcinoma50.95
DorsalRootGanglion5.35
FetalThyroid9
Fetalbrain81.55
Fetalliver12.05
Fetallung16.25
GlobusPallidus12.75
Heart8.8
Hypothalamus59.7
Kidney6.1
Leukemia_chronicMyelogenousK-56247.65
Leukemia_promyelocytic-HL-6062.2
Leukemialymphoblastic(MOLT-4)14.05
Liver8.9
Lung9.4
Lymphnode39.9
Lymphoma_burkitts(Daudi)95.3
Lymphoma_burkitts(Raji)145
MedullaOblongata21.8
OccipitalLobe47.4
OlfactoryBulb9.15
Ovary4.75
Pancreas13
PancreaticIslet16.15
ParietalLobe12
Pituitary17.6
Placenta9.75
Pons16.05
PrefrontalCortex100.75
Prostate24.25
Salivarygland14.5
SkeletalMuscle7.85
Skin5.85
SmoothMuscle13.5
Spinalcord23.2
SubthalamicNucleus19.1
SuperiorCervicalGanglion9.25
TemporalLobe21.8
Testis19.85
TestisGermCell46.75
TestisIntersitial41.45
TestisLeydigCell18.5
TestisSeminiferousTubule13.7
Thalamus12.65
Thymus26.55
Thyroid101.2
Tongue7.4
Tonsil30
Trachea16.75
TrigeminalGanglion6.75
Uterus81.15
UterusCorpus6.3
WholeBlood208.85
Wholebrain75.75
colon99.1
pineal_day100.16
pineal_night104.5
retina45.8
small_intestine55.15
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P205236
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala11.07 ± 0.33
Basal Forebrain10.52 ± 0.26
Basal Part of Pons10.17 ± 0.32
Cerebellar Cortex10.16 ± 0.21
Cerebellar Nuclei10.25 ± 0.43
Claustrum11.29 ± 0.59
Epithalamus10.13 ± 0.38
Frontal Lobe10.68 ± 0.4
Globus Pallidus10.28 ± 0.52
Hypothalamus10.37 ± 0.24
Insula10.71 ± 0.34
Limbic Lobe11.09 ± 0.46
Mesencephalon10.63 ± 0.46
Myelencephalon10.57 ± 0.36
Occipital Lobe10.61 ± 0.35
Parietal Lobe10.68 ± 0.45
Pontine Tegmentum10.63 ± 0.3
Striatum10.87 ± 0.42
Subthalamus10.62 ± 0.31
Temporal Lobe10.56 ± 0.28
Thalamus10.31 ± 0.28
White Matter9.44 ± 0.52
Mouse Brain ISH
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
2A5G_HUMAN_330 16 330 345 QLAKCVSSPHFQVAER PRIDE
PAp00009749 12 334 345 CVSSPHFQVAER Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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