AutismKB 2.0

Annotation Detail for PHF10


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:PHF10 ( BAF45A,FLJ10975,MGC111009,XAP135 )
Gene Full Name: PHD finger protein 10
Band: 6q27
Quick LinksEntrez ID:55274; OMIM: 613069; Uniprot ID:PHF10_HUMAN; ENSEMBL ID: ENSG00000130024; HGNC ID: 18250
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst1 / 6231916
fetus35 / 56401262
neonate0 / 310970 
infant1 / 2362042
juvenile1 / 5555617
adult103 / 193912153
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma2 / 17475114
breast (mammary gland) tumor3 / 9417831
cervical tumor3 / 3436687
chondrosarcoma1 / 8282312
colorectal tumor6 / 11424652
esophageal tumor2 / 17290115
gastrointestinal tumor4 / 11936933
germ cell tumor7 / 26384526
glioma5 / 10688346
head and neck tumor6 / 13630244
kidney tumor2 / 6895929
leukemia5 / 9584252
liver tumor3 / 9635931
lung tumor3 / 10312729
lymphoma3 / 7175541
non-neoplasia7 / 9725071
normal170 / 336030750
ovarian tumor3 / 7668239
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer2 / 10268019
retinoblastoma2 / 4635643
skin tumor4 / 12494932
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor12 / 90257132
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue3 / 13106228
adrenal gland3 / 3319790
ascites0 / 400150 
bladder0 / 297570 
blood1 / 1234788
bone0 / 716550 
bone marrow1 / 4880120
brain41 / 110098937
cervix3 / 4817162
connective tissue3 / 14925520
ear2 / 16212123
embryonic tissue8 / 21572237
esophagus2 / 2020998
eye12 / 21105456
heart9 / 89626100
intestine6 / 23447225
kidney8 / 21177737
larynx3 / 24145124
liver10 / 20774348
lung16 / 33697447
lymph2 / 4427045
lymph node20 / 91610218
mammary gland8 / 15327152
mouth0 / 670520 
muscle13 / 107715120
nerve2 / 15768126
ovary5 / 10205148
pancreas2 / 2148129
parathyroid3 / 20539146
pharynx0 / 413280 
pituitary gland2 / 16585120
placenta12 / 28082542
prostate5 / 18934526
salivary gland2 / 2015599
skin5 / 21057423
spleen0 / 539520 
stomach4 / 9661941
testis9 / 33044227
thymus10 / 81131123
thyroid5 / 47473105
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus19 / 23287881
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 219126_at
Cell line Expression level Expression bar
721_B_lymphoblasts46.15
Adipocyte22.6
AdrenalCortex49.7
Adrenalgland43.8
Amygdala19.4
Appendix32.25
AtrioventricularNode23.35
BDCA4+_DentriticCells149.95
Bonemarrow32.45
BronchialEpithelialCells26.45
CD105+_Endothelial170.5
CD14+_Monocytes113.65
CD19+_BCells(neg._sel.)72.9
CD33+_Myeloid82.5
CD34+298.4
CD4+_Tcells178.5
CD56+_NKCells73.45
CD71+_EarlyErythroid110.45
CD8+_Tcells207.7
CardiacMyocytes36.9
Caudatenucleus13.2
Cerebellum10.1
CerebellumPeduncles19.05
CiliaryGanglion25.2
CingulateCortex14.25
Colorectaladenocarcinoma34.7
DorsalRootGanglion32.3
FetalThyroid34.8
Fetalbrain14.8
Fetalliver32
Fetallung46.35
GlobusPallidus10.5
Heart16.2
Hypothalamus16.7
Kidney21.1
Leukemia_chronicMyelogenousK-56236.35
Leukemia_promyelocytic-HL-6023.5
Leukemialymphoblastic(MOLT-4)64.15
Liver24.6
Lung41.1
Lymphnode48.15
Lymphoma_burkitts(Daudi)63.95
Lymphoma_burkitts(Raji)25.8
MedullaOblongata12.6
OccipitalLobe11.3
OlfactoryBulb39.15
Ovary19.8
Pancreas24.1
PancreaticIslet31.45
ParietalLobe26.25
Pituitary33.85
Placenta41.05
Pons17
PrefrontalCortex17.8
Prostate51.2
Salivarygland27.6
SkeletalMuscle34.85
Skin23.1
SmoothMuscle34.7
Spinalcord24.45
SubthalamicNucleus12.35
SuperiorCervicalGanglion35.05
TemporalLobe11.4
Testis29.55
TestisGermCell42.3
TestisIntersitial45.7
TestisLeydigCell35.1
TestisSeminiferousTubule37.15
Thalamus14.95
Thymus64.9
Thyroid30.8
Tongue29.05
Tonsil50.45
Trachea30.7
TrigeminalGanglion31.7
Uterus24.4
UterusCorpus26.85
WholeBlood34.55
Wholebrain13.3
colon25.75
pineal_day46.3
pineal_night49.82
retina26.725
small_intestine27.5
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_6106_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.15 ± 0.37
Basal Forebrain6.53 ± 0.29
Basal Part of Pons5.89 ± 0.55
Cerebellar Cortex6.14 ± 0.23
Cerebellar Nuclei6.62 ± 0.44
Claustrum5.9 ± 0.44
Epithalamus6.92 ± 0.46
Frontal Lobe6.35 ± 0.38
Globus Pallidus7.31 ± 0.18
Hypothalamus6.15 ± 0.25
Insula6.45 ± 0.29
Limbic Lobe6.27 ± 0.38
Mesencephalon6.52 ± 0.34
Myelencephalon6.39 ± 0.44
Occipital Lobe6.25 ± 0.32
Parietal Lobe6.28 ± 0.38
Pontine Tegmentum6.43 ± 0.38
Striatum6.83 ± 0.28
Subthalamus6.14 ± 0.34
Temporal Lobe6.33 ± 0.32
Thalamus6.33 ± 0.48
White Matter7.58 ± 0.31
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Phf10CBCerebellum100
100
Phf10CTXCerebral cortex100
100
Phf10HIPHippocampal region100
100
Phf10HPFHippocampal formation100
100
Phf10HYHypothalamus100
100
Phf10LSXLateral septal complex100
100
Phf10MBMidbrain100
100
Phf10MYMedulla100
100
Phf10OLFOlfactory bulb100
100
Phf10PPons100
100
Phf10PALPallidum100
100
Phf10RHPRetrohippocampal region100
100
Phf10sAMYStriatum-like amygdalar nuclei100
100
Phf10STRStriatum100
100
Phf10STRdStriatum dorsal region100
100
Phf10STRvStriatum ventral region100
100
Phf10THThalamus100
100
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved