AutismKB 2.0

Annotation Detail for RHOT1


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Basic Information Top
Gene Symbol:RHOT1 ( ARHT1,FLJ11040,FLJ12633,MIRO-1 )
Gene Full Name: ras homolog gene family, member T1
Band: 17q11.2
Quick LinksEntrez ID:55288; OMIM: NA; Uniprot ID:MIRO1_HUMAN; ENSEMBL ID: ENSG00000126858; HGNC ID: 21168
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst2 / 6231932
fetus18 / 56401231
neonate1 / 3109732
infant0 / 236200 
juvenile2 / 5555635
adult77 / 193912139
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma4 / 17475228
breast (mammary gland) tumor6 / 9417863
cervical tumor0 / 343660 
chondrosarcoma4 / 8282348
colorectal tumor2 / 11424617
esophageal tumor0 / 172900 
gastrointestinal tumor8 / 11936967
germ cell tumor11 / 26384541
glioma5 / 10688346
head and neck tumor3 / 13630222
kidney tumor4 / 6895958
leukemia8 / 9584283
liver tumor3 / 9635931
lung tumor4 / 10312738
lymphoma0 / 717550 
non-neoplasia3 / 9725030
normal148 / 336030744
ovarian tumor1 / 7668213
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS4 / 12568031
prostate cancer3 / 10268029
retinoblastoma0 / 463560 
skin tumor4 / 12494932
soft tissue/muscle tissue tumor3 / 12519123
uterine tumor6 / 9025766
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland2 / 3319760
ascites2 / 4001549
bladder4 / 29757134
blood3 / 12347824
bone3 / 7165541
bone marrow9 / 48801184
brain37 / 110098933
cervix0 / 481710 
connective tissue4 / 14925526
ear0 / 162120 
embryonic tissue8 / 21572237
esophagus0 / 202090 
eye17 / 21105480
heart5 / 8962655
intestine4 / 23447217
kidney11 / 21177751
larynx2 / 2414582
liver3 / 20774314
lung17 / 33697450
lymph0 / 442700 
lymph node6 / 9161065
mammary gland7 / 15327145
mouth1 / 6705214
muscle2 / 10771518
nerve1 / 1576863
ovary3 / 10205129
pancreas10 / 21481246
parathyroid4 / 20539194
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta6 / 28082521
prostate12 / 18934563
salivary gland3 / 20155148
skin7 / 21057433
spleen1 / 5395218
stomach3 / 9661931
testis24 / 33044272
thymus2 / 8113124
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus9 / 23287838
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 222148_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts89.35
Adipocyte32.8
AdrenalCortex41.7
Adrenalgland57.1
Amygdala92.7
Appendix27.3
AtrioventricularNode11.8
BDCA4+_DentriticCells95
Bonemarrow37.1
BronchialEpithelialCells26.3
CD105+_Endothelial80.4
CD14+_Monocytes158.5
CD19+_BCells(neg._sel.)84.3
CD33+_Myeloid167.8
CD34+117.9
CD4+_Tcells48.5
CD56+_NKCells101
CD71+_EarlyErythroid88.75
CD8+_Tcells46.7
CardiacMyocytes23.75
Caudatenucleus44
Cerebellum39.1
CerebellumPeduncles53.65
CiliaryGanglion8.45
CingulateCortex64.45
Colorectaladenocarcinoma35
DorsalRootGanglion22.3
FetalThyroid48.75
Fetalbrain74.3
Fetalliver34
Fetallung47.05
GlobusPallidus34.75
Heart28.45
Hypothalamus78.1
Kidney24.05
Leukemia_chronicMyelogenousK-562110.15
Leukemia_promyelocytic-HL-6056.7
Leukemialymphoblastic(MOLT-4)75.9
Liver21.3
Lung17.4
Lymphnode29.1
Lymphoma_burkitts(Daudi)51.5
Lymphoma_burkitts(Raji)62.55
MedullaOblongata62.55
OccipitalLobe82.1
OlfactoryBulb38.7
Ovary13.2
Pancreas26.2
PancreaticIslet33.95
ParietalLobe49.75
Pituitary63.9
Placenta27.9
Pons51.05
PrefrontalCortex171.1
Prostate34.65
Salivarygland29.35
SkeletalMuscle28.5
Skin24.9
SmoothMuscle27.6
Spinalcord45.9
SubthalamicNucleus48.45
SuperiorCervicalGanglion33.7
TemporalLobe54.1
Testis25.15
TestisGermCell44.9
TestisIntersitial22.45
TestisLeydigCell33.25
TestisSeminiferousTubule33.55
Thalamus52.55
Thymus22.35
Thyroid74.75
Tongue27.1
Tonsil31.8
Trachea31.1
TrigeminalGanglion31.85
Uterus43.1
UterusCorpus27.95
WholeBlood109.75
Wholebrain71.85
colon55.35
pineal_day254.68
pineal_night198.6
retina52.475
small_intestine52.8
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_15211_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala9.71 ± 0.2
Basal Forebrain9.39 ± 0.18
Basal Part of Pons9.54 ± 0.26
Cerebellar Cortex9.35 ± 0.27
Cerebellar Nuclei9.58 ± 0.37
Claustrum9.86 ± 0.39
Epithalamus9.05 ± 0.24
Frontal Lobe9.44 ± 0.29
Globus Pallidus9.5 ± 0.2
Hypothalamus9.23 ± 0.23
Insula9.5 ± 0.28
Limbic Lobe9.8 ± 0.28
Mesencephalon9.49 ± 0.32
Myelencephalon9.51 ± 0.27
Occipital Lobe9.9 ± 0.27
Parietal Lobe9.61 ± 0.29
Pontine Tegmentum9.58 ± 0.29
Striatum9.71 ± 0.25
Subthalamus9.63 ± 0.18
Temporal Lobe9.54 ± 0.25
Thalamus9.55 ± 0.26
White Matter9.67 ± 0.43
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Rhot1CBCerebellum30.87
47.28
Rhot1CTXCerebral cortex64.42
47.72
Rhot1HIPHippocampal region37.1
55.35
Rhot1HPFHippocampal formation44.88
50.87
Rhot1HYHypothalamus10.72
8.29
Rhot1LSXLateral septal complex19.94
16.05
Rhot1MBMidbrain22.38
20.89
Rhot1MYMedulla28.78
34.77
Rhot1OLFOlfactory bulb34.37
25.89
Rhot1PPons20.19
22.95
Rhot1PALPallidum15.41
12.77
Rhot1RHPRetrohippocampal region58.47
46
Rhot1sAMYStriatum-like amygdalar nuclei30.9
22.26
Rhot1STRStriatum30.11
21.16
Rhot1STRdStriatum dorsal region33.33
23.59
Rhot1STRvStriatum ventral region23.36
15.31
Rhot1THThalamus29.66
24.78
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
MIRO1_HUMAN_92 15 92 106 VTSRWIPLINERTDK PRIDE
PAp00000782 15 165 179 AVLHPTGPLYCPEEK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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