AutismKB 2.0

Annotation Detail for GIMAP4


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Basic Information Top
Gene Symbol:GIMAP4 ( FLJ11110,HIMAP4,IAN1,IMAP4,hIAN1 )
Gene Full Name: GTPase, IMAP family member 4
Band: 7q36.1
Quick LinksEntrez ID:55303; OMIM: 608087; Uniprot ID:GIMA4_HUMAN; ENSEMBL ID: ENSG00000133574; HGNC ID: 21872
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus7 / 56401212
neonate5 / 31097160
infant0 / 236200 
juvenile1 / 5555617
adult53 / 193912127
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus0 / 5640120 
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult3 / 19391211
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor3 / 3436687
chondrosarcoma1 / 8282312
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor1 / 2638453
glioma0 / 1068830 
head and neck tumor2 / 13630214
kidney tumor1 / 6895914
leukemia2 / 9584220
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia8 / 9725082
normal174 / 336030751
ovarian tumor0 / 766820 
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS2 / 12568015
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor2 / 9025722
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor0 / 2638450 
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal4 / 33603071
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder3 / 29757100
blood40 / 123478323
bone1 / 7165513
bone marrow0 / 488010 
brain35 / 110098931
cervix3 / 4817162
connective tissue13 / 14925587
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye1 / 2110544
heart11 / 89626122
intestine13 / 23447255
kidney3 / 21177714
larynx0 / 241450 
liver2 / 2077439
lung15 / 33697444
lymph0 / 442700 
lymph node1 / 9161010
mammary gland3 / 15327119
mouth0 / 670520 
muscle4 / 10771537
nerve0 / 157680 
ovary0 / 1020510 
pancreas1 / 2148124
parathyroid3 / 20539146
pharynx9 / 41328217
pituitary gland0 / 165850 
placenta30 / 280825106
prostate2 / 18934510
salivary gland0 / 201550 
skin3 / 21057414
spleen10 / 53952185
stomach4 / 9661941
testis1 / 3304423
thymus3 / 8113136
thyroid2 / 4747342
tonsil2 / 16999117
trachea2 / 5241338
umbilical cord3 / 13680219
uterus9 / 23287838
vascular2 / 5178038
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain0 / 11009890 
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye0 / 2110540 
heart0 / 896260 
intestine0 / 2344720 
kidney1 / 2117774
larynx0 / 241450 
liver0 / 2077430 
lung0 / 3369740 
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta3 / 28082510
prostate0 / 1893450 
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach0 / 966190 
testis0 / 3304420 
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 219243_at
Cell line Expression level Expression bar
721_B_lymphoblasts7.55
Adipocyte6.1
AdrenalCortex7
Adrenalgland5.55
Amygdala6.6
Appendix7.9
AtrioventricularNode5.65
BDCA4+_DentriticCells11.95
Bonemarrow7.2
BronchialEpithelialCells6
CD105+_Endothelial6.3
CD14+_Monocytes85.45
CD19+_BCells(neg._sel.)6.4
CD33+_Myeloid48.35
CD34+7.6
CD4+_Tcells62.05
CD56+_NKCells79.95
CD71+_EarlyErythroid5.85
CD8+_Tcells48.15
CardiacMyocytes9.1
Caudatenucleus5.65
Cerebellum5.15
CerebellumPeduncles7.3
CiliaryGanglion5.25
CingulateCortex6.6
Colorectaladenocarcinoma6.3
DorsalRootGanglion5.5
FetalThyroid6.2
Fetalbrain6.2
Fetalliver5.65
Fetallung8
GlobusPallidus4.75
Heart9.3
Hypothalamus7
Kidney5.5
Leukemia_chronicMyelogenousK-5625.6
Leukemia_promyelocytic-HL-605.55
Leukemialymphoblastic(MOLT-4)4.95
Liver9.2
Lung8.35
Lymphnode22.3
Lymphoma_burkitts(Daudi)8
Lymphoma_burkitts(Raji)8.9
MedullaOblongata5.75
OccipitalLobe5.65
OlfactoryBulb5.05
Ovary4.5
Pancreas5.15
PancreaticIslet6.85
ParietalLobe6.75
Pituitary7.4
Placenta8.85
Pons6.05
PrefrontalCortex7.45
Prostate7.25
Salivarygland7.4
SkeletalMuscle8.7
Skin5.45
SmoothMuscle7.05
Spinalcord6.85
SubthalamicNucleus5.85
SuperiorCervicalGanglion9.15
TemporalLobe5.9
Testis5.4
TestisGermCell5.05
TestisIntersitial5.3
TestisLeydigCell6.35
TestisSeminiferousTubule5.35
Thalamus6.75
Thymus5.05
Thyroid8.1
Tongue6.45
Tonsil10.9
Trachea5.7
TrigeminalGanglion6.7
Uterus10.05
UterusCorpus5.8
WholeBlood242.65
Wholebrain5.4
colon6.35
pineal_day7.68
pineal_night7.5
retina7.625
small_intestine11.05
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_13813_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.92 ± 0.97
Basal Forebrain2.38 ± 0.28
Basal Part of Pons2.29 ± 0.6
Cerebellar Cortex2.13 ± 0.47
Cerebellar Nuclei3.23 ± 0.66
Claustrum3.25 ± 1.1
Epithalamus2.59 ± 0.92
Frontal Lobe2.53 ± 0.76
Globus Pallidus4.03 ± 0.52
Hypothalamus2.31 ± 0.85
Insula2.05 ± 0.53
Limbic Lobe2.48 ± 0.77
Mesencephalon2.81 ± 0.8
Myelencephalon2.73 ± 0.71
Occipital Lobe2.62 ± 0.85
Parietal Lobe2.63 ± 0.7
Pontine Tegmentum2.67 ± 0.78
Striatum2.95 ± 0.6
Subthalamus2.87 ± 0.09
Temporal Lobe2.57 ± 0.8
Thalamus2.64 ± 0.7
White Matter3.9 ± 0.97
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Gimap4CBCerebellum24.72
31.26
Gimap4CTXCerebral cortex22.79
17.44
Gimap4HIPHippocampal region12.73
13.27
Gimap4HPFHippocampal formation19.6
19.04
Gimap4HYHypothalamus9.47
7.6
Gimap4LSXLateral septal complex14.71
11.51
Gimap4MBMidbrain11.2
10.61
Gimap4MYMedulla19.7
21.94
Gimap4OLFOlfactory bulb31.15
26.45
Gimap4PPons14.28
15.4
Gimap4PALPallidum6
5.56
Gimap4RHPRetrohippocampal region32.59
28.43
Gimap4sAMYStriatum-like amygdalar nuclei2.44
1.61
Gimap4STRStriatum13.26
10.2
Gimap4STRdStriatum dorsal region13.83
10.8
Gimap4STRvStriatum ventral region17.11
12.49
Gimap4THThalamus8.37
7.38
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
GIMA4_HUMAN_0 0 0 0 CILLTSPGPHALLLVVPLGR PRIDE
GIMA4_HUMAN_105 20 105 124 CILLTSPGPHALLLVVPLGR PRIDE
GIMA4_HUMAN_146 9 146 154 SFMILIFTR PRIDE
GIMA4_HUMAN_155 14 155 168 KDDLGDTNLHDYLR PRIDE
GIMA4_HUMAN_169 23 169 191 EAPEDIQDLMDIFGDRYCALNNK PRIDE
GIMA4_HUMAN_2 22 2 23 AAQYGSMSFNPSTPGASYGPGR PRIDE
GIMA4_HUMAN_202 9 202 210 AQLLGLIQR PRIDE
GIMA4_HUMAN_236 10 236 245 QTQAMQELHR PRIDE
GIMA4_HUMAN_281 12 281 292 KLAEQEAHYAVR PRIDE
PAp00378400 12 282 293 KLAEQEAHYAVR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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