AutismKB 2.0

Annotation Detail for PRR5-ARHGAP8


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Basic Information Top
Gene Symbol:PRR5-ARHGAP8 ( - )
Gene Full Name: PRR5-ARHGAP8 readthrough
Band: 22q13.31
Quick LinksEntrez ID:553158; OMIM: NA; Uniprot ID:F8W6F3_HUMAN; ENSEMBL ID: ENSG00000248405; HGNC ID: 34512
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Microarray in BioGPS Top
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  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 205980_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts5.2
Adipocyte4.2
AdrenalCortex4.8
Adrenalgland3.7
Amygdala4.4
Appendix4.75
AtrioventricularNode3.55
BDCA4+_DentriticCells4.55
Bonemarrow4.4
BronchialEpithelialCells4.95
CD105+_Endothelial4.4
CD14+_Monocytes4.6
CD19+_BCells(neg._sel.)4.5
CD33+_Myeloid5.6
CD34+5.6
CD4+_Tcells4.55
CD56+_NKCells5.3
CD71+_EarlyErythroid4.1
CD8+_Tcells4.1
CardiacMyocytes6.3
Caudatenucleus3.9
Cerebellum3.55
CerebellumPeduncles5
CiliaryGanglion3.4
CingulateCortex4.55
Colorectaladenocarcinoma4.65
DorsalRootGanglion3.6
FetalThyroid4.8
Fetalbrain4.3
Fetalliver3.75
Fetallung3.7
GlobusPallidus3.3
Heart5.9
Hypothalamus4.6
Kidney3.7
Leukemia_chronicMyelogenousK-5623.95
Leukemia_promyelocytic-HL-603.85
Leukemialymphoblastic(MOLT-4)3.4
Liver6.15
Lung7.7
Lymphnode3.65
Lymphoma_burkitts(Daudi)5.65
Lymphoma_burkitts(Raji)6.55
MedullaOblongata3.9
OccipitalLobe3.85
OlfactoryBulb3.45
Ovary3.05
Pancreas3.55
PancreaticIslet4.7
ParietalLobe4.65
Pituitary5.05
Placenta19.5
Pons4.1
PrefrontalCortex5.25
Prostate28.05
Salivarygland3.65
SkeletalMuscle5.6
Skin3.5
SmoothMuscle4.85
Spinalcord4.55
SubthalamicNucleus4
SuperiorCervicalGanglion5.5
TemporalLobe3.95
Testis3.7
TestisGermCell3.65
TestisIntersitial3.65
TestisLeydigCell4.6
TestisSeminiferousTubule3.7
Thalamus4.45
Thymus3.3
Thyroid31.1
Tongue4.5
Tonsil4.25
Trachea3.6
TrigeminalGanglion4.75
Uterus3.55
UterusCorpus4.05
WholeBlood4.7
Wholebrain3.55
colon24.9
pineal_day5.38
pineal_night5.26
retina5.275
small_intestine4.25
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_1944_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.57 ± 0.95
Basal Forebrain3.12 ± 0.45
Basal Part of Pons2.84 ± 0.38
Cerebellar Cortex3.09 ± 0.71
Cerebellar Nuclei3.48 ± 0.71
Claustrum4.23 ± 0.89
Epithalamus2.92 ± 0.82
Frontal Lobe3.26 ± 0.78
Globus Pallidus4.39 ± 0.78
Hypothalamus3.42 ± 0.45
Insula3.13 ± 0.53
Limbic Lobe3.59 ± 0.77
Mesencephalon3.43 ± 0.82
Myelencephalon3.39 ± 0.8
Occipital Lobe3.33 ± 0.64
Parietal Lobe3.26 ± 0.94
Pontine Tegmentum3.34 ± 0.77
Striatum3.24 ± 0.8
Subthalamus3.51 ± 0.71
Temporal Lobe3.28 ± 0.74
Thalamus3.25 ± 0.77
White Matter3.08 ± 0.66
Mouse Brain ISH
Peptide Top

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  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018