AutismKB 2.0

Annotation Detail for C19orf66


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Basic Information Top
Gene Symbol:C19orf66 ( FLJ11286,FLJ40743 )
Gene Full Name: chromosome 19 open reading frame 66
Band: 19p13.2
Quick LinksEntrez ID:55337; OMIM: NA; Uniprot ID:CS066_HUMAN; ENSEMBL ID: ENSG00000130813; HGNC ID: 25649
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst1 / 6231916
fetus17 / 56401230
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult84 / 193912143
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor3 / 9417831
cervical tumor0 / 343660 
chondrosarcoma4 / 8282348
colorectal tumor3 / 11424626
esophageal tumor0 / 172900 
gastrointestinal tumor2 / 11936916
germ cell tumor6 / 26384522
glioma2 / 10688318
head and neck tumor2 / 13630214
kidney tumor2 / 6895929
leukemia3 / 9584231
liver tumor4 / 9635941
lung tumor4 / 10312738
lymphoma2 / 7175527
non-neoplasia4 / 9725041
normal123 / 336030736
ovarian tumor7 / 7668291
pancreatic tumor5 / 10461647
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer6 / 10268058
retinoblastoma0 / 463560 
skin tumor8 / 12494964
soft tissue/muscle tissue tumor5 / 12519139
uterine tumor6 / 9025766
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland4 / 33197120
ascites1 / 4001524
bladder2 / 2975767
blood4 / 12347832
bone2 / 7165527
bone marrow0 / 488010 
brain34 / 110098930
cervix2 / 4817141
connective tissue6 / 14925540
ear0 / 162120 
embryonic tissue5 / 21572223
esophagus0 / 202090 
eye4 / 21105418
heart1 / 8962611
intestine6 / 23447225
kidney4 / 21177718
larynx1 / 2414541
liver15 / 20774372
lung13 / 33697438
lymph1 / 4427022
lymph node6 / 9161065
mammary gland3 / 15327119
mouth0 / 670520 
muscle0 / 1077150 
nerve2 / 15768126
ovary7 / 10205168
pancreas5 / 21481223
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta11 / 28082539
prostate11 / 18934558
salivary gland0 / 201550 
skin17 / 21057480
spleen8 / 53952148
stomach1 / 9661910
testis3 / 3304429
thymus2 / 8113124
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus17 / 23287872
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 53720_at
Cell line Expression level Expression bar
721_B_lymphoblasts85.35
Adipocyte17.75
AdrenalCortex30.9
Adrenalgland22.6
Amygdala43.35
Appendix39.35
AtrioventricularNode33.9
BDCA4+_DentriticCells49.15
Bonemarrow27.05
BronchialEpithelialCells13.9
CD105+_Endothelial43.25
CD14+_Monocytes80.95
CD19+_BCells(neg._sel.)102.45
CD33+_Myeloid100.4
CD34+51.6
CD4+_Tcells229.2
CD56+_NKCells265.6
CD71+_EarlyErythroid15.15
CD8+_Tcells346.5
CardiacMyocytes24.9
Caudatenucleus25.6
Cerebellum23.95
CerebellumPeduncles24.3
CiliaryGanglion35.4
CingulateCortex34.5
Colorectaladenocarcinoma20.75
DorsalRootGanglion31
FetalThyroid27.8
Fetalbrain19.75
Fetalliver24.4
Fetallung26.4
GlobusPallidus23.65
Heart40.05
Hypothalamus50.7
Kidney26.35
Leukemia_chronicMyelogenousK-56221.8
Leukemia_promyelocytic-HL-6023.65
Leukemialymphoblastic(MOLT-4)33.25
Liver205.75
Lung62.55
Lymphnode84.95
Lymphoma_burkitts(Daudi)56.35
Lymphoma_burkitts(Raji)39.75
MedullaOblongata32.85
OccipitalLobe24.25
OlfactoryBulb28.85
Ovary20.9
Pancreas14.1
PancreaticIslet26.65
ParietalLobe30.25
Pituitary31.4
Placenta13.4
Pons27.55
PrefrontalCortex54.25
Prostate29.9
Salivarygland26
SkeletalMuscle40.05
Skin27.4
SmoothMuscle30.6
Spinalcord32.8
SubthalamicNucleus33.05
SuperiorCervicalGanglion42.6
TemporalLobe37.3
Testis16.75
TestisGermCell13.1
TestisIntersitial15.6
TestisLeydigCell23.4
TestisSeminiferousTubule21.1
Thalamus27.95
Thymus41.5
Thyroid43.6
Tongue30.4
Tonsil34.25
Trachea17.5
TrigeminalGanglion29.55
Uterus38.9
UterusCorpus23.45
WholeBlood54.25
Wholebrain42.3
colon20.15
pineal_day67.5
pineal_night85.78
retina42.975
small_intestine35.65
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P236949
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.35 ± 0.48
Basal Forebrain3.9 ± 0.54
Basal Part of Pons4.23 ± 0.37
Cerebellar Cortex3.94 ± 0.48
Cerebellar Nuclei3.85 ± 0.37
Claustrum4.15 ± 0.67
Epithalamus4.13 ± 0.77
Frontal Lobe4.39 ± 0.54
Globus Pallidus3.58 ± 0.8
Hypothalamus4.32 ± 0.53
Insula4.28 ± 0.46
Limbic Lobe4.19 ± 0.64
Mesencephalon4.2 ± 0.62
Myelencephalon4.2 ± 0.62
Occipital Lobe3.92 ± 0.54
Parietal Lobe4.23 ± 0.69
Pontine Tegmentum4.24 ± 0.67
Striatum4.1 ± 0.62
Subthalamus3.66 ± 0.59
Temporal Lobe4.3 ± 0.55
Thalamus4.03 ± 0.63
White Matter3.02 ± 0.37
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
A230050P20RikCBCerebellum89.62
100
A230050P20RikCTXCerebral cortex100
100
A230050P20RikHIPHippocampal region100
100
A230050P20RikHPFHippocampal formation100
100
A230050P20RikHYHypothalamus100
100
A230050P20RikLSXLateral septal complex100
100
A230050P20RikMBMidbrain100
100
A230050P20RikMYMedulla100
100
A230050P20RikOLFOlfactory bulb100
100
A230050P20RikPPons100
100
A230050P20RikPALPallidum87.14
84.14
A230050P20RikRHPRetrohippocampal region100
100
A230050P20RiksAMYStriatum-like amygdalar nuclei100
100
A230050P20RikSTRStriatum99.25
81.79
A230050P20RikSTRdStriatum dorsal region95.7
76.83
A230050P20RikSTRvStriatum ventral region91.2
76.12
A230050P20RikTHThalamus100
100
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00042691 15 199 213 STHTHSCSAADCYNR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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