AutismKB 2.0

Annotation Detail for PLCXD1


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Basic Information Top
Gene Symbol:PLCXD1 ( FLJ11323 )
Gene Full Name: phosphatidylinositol-specific phospholipase C, X domain containing 1
Band: Xp22.33 and Yp11.32
Quick LinksEntrez ID:55344; OMIM: NA; Uniprot ID:PLCX1_HUMAN; ENSEMBL ID: ENSG00000182378,ENSG00000240120; HGNC ID: 23148
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body3 / 7076142
blastocyst3 / 6231948
fetus15 / 56401226
neonate0 / 310970 
infant4 / 23620169
juvenile0 / 555560 
adult47 / 193912124
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor2 / 9417821
cervical tumor1 / 3436629
chondrosarcoma0 / 828230 
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor9 / 26384534
glioma7 / 10688365
head and neck tumor3 / 13630222
kidney tumor1 / 6895914
leukemia6 / 9584262
liver tumor2 / 9635920
lung tumor5 / 10312748
lymphoma2 / 7175527
non-neoplasia0 / 972500 
normal77 / 336030722
ovarian tumor2 / 7668226
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS4 / 12568031
prostate cancer0 / 1026800 
retinoblastoma1 / 4635621
skin tumor4 / 12494932
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor5 / 9025755
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder1 / 2975733
blood2 / 12347816
bone1 / 7165513
bone marrow2 / 4880140
brain25 / 110098922
cervix2 / 4817141
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue8 / 21572237
esophagus0 / 202090 
eye2 / 2110549
heart4 / 8962644
intestine5 / 23447221
kidney4 / 21177718
larynx0 / 241450 
liver2 / 2077439
lung11 / 33697432
lymph2 / 4427045
lymph node8 / 9161087
mammary gland3 / 15327119
mouth0 / 670520 
muscle3 / 10771527
nerve0 / 157680 
ovary4 / 10205139
pancreas1 / 2148124
parathyroid0 / 205390 
pharynx3 / 4132872
pituitary gland0 / 165850 
placenta9 / 28082532
prostate3 / 18934515
salivary gland0 / 201550 
skin4 / 21057418
spleen1 / 5395218
stomach2 / 9661920
testis6 / 33044218
thymus1 / 8113112
thyroid1 / 4747321
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus7 / 23287830
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 218951_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts883.75
Adipocyte35.9
AdrenalCortex34.55
Adrenalgland28.65
Amygdala39.65
Appendix28.55
AtrioventricularNode25.1
BDCA4+_DentriticCells35.75
Bonemarrow55.8
BronchialEpithelialCells33
CD105+_Endothelial89.05
CD14+_Monocytes33.7
CD19+_BCells(neg._sel.)43.5
CD33+_Myeloid44.4
CD34+282.8
CD4+_Tcells81
CD56+_NKCells44.55
CD71+_EarlyErythroid40.05
CD8+_Tcells118.05
CardiacMyocytes36.3
Caudatenucleus41.8
Cerebellum38.3
CerebellumPeduncles60.05
CiliaryGanglion24.4
CingulateCortex35.3
Colorectaladenocarcinoma36.55
DorsalRootGanglion26
FetalThyroid31.65
Fetalbrain57.3
Fetalliver30.35
Fetallung46.75
GlobusPallidus24.9
Heart35.05
Hypothalamus42.1
Kidney32
Leukemia_chronicMyelogenousK-56292.8
Leukemia_promyelocytic-HL-60161.9
Leukemialymphoblastic(MOLT-4)72.4
Liver44.4
Lung53.25
Lymphnode50
Lymphoma_burkitts(Daudi)68.55
Lymphoma_burkitts(Raji)139.2
MedullaOblongata41.65
OccipitalLobe33.3
OlfactoryBulb25.35
Ovary22.35
Pancreas32.4
PancreaticIslet35.85
ParietalLobe49.35
Pituitary39.1
Placenta39.65
Pons47.85
PrefrontalCortex44.7
Prostate39.55
Salivarygland27.15
SkeletalMuscle37.8
Skin25.45
SmoothMuscle31.15
Spinalcord39.55
SubthalamicNucleus34.55
SuperiorCervicalGanglion39.85
TemporalLobe38.8
Testis30.15
TestisGermCell29
TestisIntersitial28.05
TestisLeydigCell37.85
TestisSeminiferousTubule30.55
Thalamus36.55
Thymus44.85
Thyroid35.2
Tongue32.35
Tonsil36.4
Trachea28
TrigeminalGanglion35.4
Uterus22.05
UterusCorpus31.3
WholeBlood33.55
Wholebrain45.35
colon27.8
pineal_day42.06
pineal_night41.66
retina40.85
small_intestine23.05
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_8298_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.64 ± 0.47
Basal Forebrain6.8 ± 0.31
Basal Part of Pons6.79 ± 0.4
Cerebellar Cortex7.02 ± 0.39
Cerebellar Nuclei6.58 ± 0.46
Claustrum6.17 ± 0.65
Epithalamus6.45 ± 0.47
Frontal Lobe6.74 ± 0.44
Globus Pallidus6.8 ± 0.21
Hypothalamus6.59 ± 0.36
Insula6.83 ± 0.26
Limbic Lobe6.87 ± 0.39
Mesencephalon6.64 ± 0.41
Myelencephalon6.75 ± 0.44
Occipital Lobe6.82 ± 0.36
Parietal Lobe6.73 ± 0.38
Pontine Tegmentum6.61 ± 0.43
Striatum6.57 ± 0.35
Subthalamus6.31 ± 0.37
Temporal Lobe6.87 ± 0.35
Thalamus6.6 ± 0.43
White Matter8.3 ± 0.24
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Plcxd1CBCerebellum48.94
68.11
Plcxd1CTXCerebral cortex93.66
79.03
Plcxd1HIPHippocampal region57.99
86.93
Plcxd1HPFHippocampal formation67.1
78.63
Plcxd1HYHypothalamus81.32
77.51
Plcxd1LSXLateral septal complex84.49
71.54
Plcxd1MBMidbrain80.22
81.67
Plcxd1MYMedulla87.63
100
Plcxd1OLFOlfactory bulb83.77
73.15
Plcxd1PPons76.5
85.25
Plcxd1PALPallidum74.92
74.36
Plcxd1RHPRetrohippocampal region83.57
70.18
Plcxd1sAMYStriatum-like amygdalar nuclei100
85.88
Plcxd1STRStriatum70.64
55.65
Plcxd1STRdStriatum dorsal region67
53.11
Plcxd1STRvStriatum ventral region65.96
47.1
Plcxd1THThalamus62.93
56.16
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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