AutismKB 2.0

Annotation Detail for TCP11L1


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Basic Information Top
Gene Symbol:TCP11L1 ( FLJ11336,FLJ11386,dJ85M6.3 )
Gene Full Name: t-complex 11 (mouse)-like 1
Band: 11p13
Quick LinksEntrez ID:55346; OMIM: NA; Uniprot ID:T11L1_HUMAN; ENSEMBL ID: ENSG00000176148; HGNC ID: 25655
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst0 / 623190 
fetus13 / 56401223
neonate2 / 3109764
infant0 / 236200 
juvenile2 / 5555635
adult40 / 193912120
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor2 / 11424617
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor4 / 26384515
glioma2 / 10688318
head and neck tumor2 / 13630214
kidney tumor0 / 689590 
leukemia1 / 9584210
liver tumor0 / 963590 
lung tumor1 / 1031279
lymphoma0 / 717550 
non-neoplasia1 / 9725010
normal88 / 336030726
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS2 / 12568015
prostate cancer0 / 1026800 
retinoblastoma2 / 4635643
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor4 / 12519131
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland1 / 3319730
ascites0 / 400150 
bladder0 / 297570 
blood2 / 12347816
bone0 / 716550 
bone marrow1 / 4880120
brain38 / 110098934
cervix0 / 481710 
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue4 / 21572218
esophagus0 / 202090 
eye6 / 21105428
heart2 / 8962622
intestine5 / 23447221
kidney2 / 2117779
larynx0 / 241450 
liver3 / 20774314
lung3 / 3369748
lymph0 / 442700 
lymph node0 / 916100 
mammary gland3 / 15327119
mouth1 / 6705214
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas1 / 2148124
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta6 / 28082521
prostate2 / 18934510
salivary gland0 / 201550 
skin7 / 21057433
spleen1 / 5395218
stomach1 / 9661910
testis5 / 33044215
thymus1 / 8113112
thyroid1 / 4747321
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus3 / 23287812
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 205797_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts8.05
Adipocyte8.25
AdrenalCortex10.1
Adrenalgland7.15
Amygdala9.15
Appendix9.25
AtrioventricularNode7.25
BDCA4+_DentriticCells9.1
Bonemarrow8.75
BronchialEpithelialCells8.5
CD105+_Endothelial7.7
CD14+_Monocytes9
CD19+_BCells(neg._sel.)8.65
CD33+_Myeloid10.2
CD34+9.5
CD4+_Tcells8.15
CD56+_NKCells9.4
CD71+_EarlyErythroid8
CD8+_Tcells6.85
CardiacMyocytes13.5
Caudatenucleus7.5
Cerebellum7
CerebellumPeduncles11.2
CiliaryGanglion6.4
CingulateCortex8.8
Colorectaladenocarcinoma8.65
DorsalRootGanglion6.75
FetalThyroid8.35
Fetalbrain8.65
Fetalliver8.7
Fetallung7.5
GlobusPallidus6.2
Heart13.1
Hypothalamus9.45
Kidney6.8
Leukemia_chronicMyelogenousK-5627.75
Leukemia_promyelocytic-HL-607.55
Leukemialymphoblastic(MOLT-4)8.75
Liver13.6
Lung9.6
Lymphnode9.05
Lymphoma_burkitts(Daudi)11.3
Lymphoma_burkitts(Raji)12.15
MedullaOblongata7.65
OccipitalLobe7.3
OlfactoryBulb6.75
Ovary6.45
Pancreas7.1
PancreaticIslet9.15
ParietalLobe9.35
Pituitary10.4
Placenta8.65
Pons8.1
PrefrontalCortex9.65
Prostate10.2
Salivarygland6.8
SkeletalMuscle14
Skin6.4
SmoothMuscle9.8
Spinalcord9.2
SubthalamicNucleus8
SuperiorCervicalGanglion11.7
TemporalLobe7.8
Testis9.2
TestisGermCell7.25
TestisIntersitial7.2
TestisLeydigCell8.7
TestisSeminiferousTubule7.35
Thalamus8.2
Thymus7.65
Thyroid10.9
Tongue10.4
Tonsil8.7
Trachea8.45
TrigeminalGanglion10.15
Uterus6.95
UterusCorpus9.8
WholeBlood9.25
Wholebrain7.05
colon8.15
pineal_day9.2
pineal_night9.04
retina10.175
small_intestine7.85
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_12127_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.06 ± 0.3
Basal Forebrain6.91 ± 0.31
Basal Part of Pons7.26 ± 0.28
Cerebellar Cortex6.82 ± 0.26
Cerebellar Nuclei7.09 ± 0.26
Claustrum7.57 ± 0.47
Epithalamus6.24 ± 0.61
Frontal Lobe6.92 ± 0.39
Globus Pallidus6.85 ± 0.3
Hypothalamus7.01 ± 0.37
Insula6.96 ± 0.36
Limbic Lobe7.14 ± 0.36
Mesencephalon7.08 ± 0.37
Myelencephalon6.94 ± 0.41
Occipital Lobe7.18 ± 0.34
Parietal Lobe7.08 ± 0.35
Pontine Tegmentum6.9 ± 0.37
Striatum6.44 ± 0.38
Subthalamus6.97 ± 0.23
Temporal Lobe7.03 ± 0.33
Thalamus6.96 ± 0.32
White Matter7.26 ± 0.52
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Tcp11l1CBCerebellum25.04
34.2
Tcp11l1CTXCerebral cortex29.51
21.32
Tcp11l1HIPHippocampal region22.3
22.91
Tcp11l1HPFHippocampal formation30.79
28.19
Tcp11l1HYHypothalamus11.83
9.06
Tcp11l1LSXLateral septal complex7.06
5.07
Tcp11l1MBMidbrain15.35
15.21
Tcp11l1MYMedulla35.14
43.41
Tcp11l1OLFOlfactory bulb33.2
26.43
Tcp11l1PPons28.54
32.35
Tcp11l1PALPallidum15.42
14.79
Tcp11l1RHPRetrohippocampal region48.06
38.04
Tcp11l1sAMYStriatum-like amygdalar nuclei9.8
7.09
Tcp11l1STRStriatum7.88
6.28
Tcp11l1STRdStriatum dorsal region8.22
6.91
Tcp11l1STRvStriatum ventral region5.76
3.98
Tcp11l1THThalamus15.89
12.42
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00095330 22 111 132 AFWDCLSVQLSEDPPAYDHAIK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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