Annotation Detail for LAPTM4B
Basic Information Top
| Gene Symbol: | LAPTM4B ( LAPTM4beta,LC27 ) |
|---|---|
| Gene Full Name: | lysosomal protein transmembrane 4 beta |
| Band: | 8q22.1 |
| Quick Links | Entrez ID:55353; OMIM: 613296; Uniprot ID:LAP4B_HUMAN; ENSEMBL ID: ENSG00000104341; HGNC ID: 13646 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.492314
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
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| embryoid body | 29 / 70761 | 409 | |
| blastocyst | 22 / 62319 | 353 | |
| fetus | 85 / 564012 | 150 | |
| neonate | 5 / 31097 | 160 | |
| infant | 5 / 23620 | 211 | |
| juvenile | 16 / 55556 | 287 | |
| adult | 369 / 1939121 | 190 |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
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| adrenal tumor | 6 / 12794 | 468 | |
| bladder carcinoma | 1 / 17475 | 57 | |
| breast (mammary gland) tumor | 11 / 94178 | 116 | |
| cervical tumor | 12 / 34366 | 349 | |
| chondrosarcoma | 17 / 82823 | 205 | |
| colorectal tumor | 15 / 114246 | 131 | |
| esophageal tumor | 2 / 17290 | 115 | |
| gastrointestinal tumor | 61 / 119369 | 511 | |
| germ cell tumor | 88 / 263845 | 333 | |
| glioma | 24 / 106883 | 224 | |
| head and neck tumor | 14 / 136302 | 102 | |
| kidney tumor | 27 / 68959 | 391 | |
| leukemia | 5 / 95842 | 52 | |
| liver tumor | 17 / 96359 | 176 | |
| lung tumor | 25 / 103127 | 242 | |
| lymphoma | 1 / 71755 | 13 | |
| non-neoplasia | 7 / 97250 | 71 | |
| normal | 498 / 3360307 | 148 | |
| ovarian tumor | 39 / 76682 | 508 | |
| pancreatic tumor | 28 / 104616 | 267 | |
| primitive neuroectodermal tumor of the CNS | 54 / 125680 | 429 | |
| prostate cancer | 12 / 102680 | 116 | |
| retinoblastoma | 18 / 46356 | 388 | |
| skin tumor | 37 / 124949 | 296 | |
| soft tissue/muscle tissue tumor | 54 / 125191 | 431 | |
| uterine tumor | 58 / 90257 | 642 |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
![]() | |||
| adipose tissue | 0 / 13106 | 0 | |
| adrenal gland | 8 / 33197 | 240 | |
| ascites | 16 / 40015 | 399 | |
| bladder | 6 / 29757 | 201 | |
| blood | 4 / 123478 | 32 | |
| bone | 22 / 71655 | 307 | |
| bone marrow | 2 / 48801 | 40 | |
| brain | 154 / 1100989 | 139 | |
| cervix | 16 / 48171 | 332 | |
| connective tissue | 49 / 149255 | 328 | |
| ear | 4 / 16212 | 246 | |
| embryonic tissue | 92 / 215722 | 426 | |
| esophagus | 2 / 20209 | 98 | |
| eye | 80 / 211054 | 379 | |
| heart | 41 / 89626 | 457 | |
| intestine | 36 / 234472 | 153 | |
| kidney | 48 / 211777 | 226 | |
| larynx | 5 / 24145 | 207 | |
| liver | 29 / 207743 | 139 | |
| lung | 62 / 336974 | 183 | |
| lymph | 0 / 44270 | 0 | |
| lymph node | 6 / 91610 | 65 | |
| mammary gland | 13 / 153271 | 84 | |
| mouth | 7 / 67052 | 104 | |
| muscle | 18 / 107715 | 167 | |
| nerve | 2 / 15768 | 126 | |
| ovary | 46 / 102051 | 450 | |
| pancreas | 40 / 214812 | 186 | |
| parathyroid | 11 / 20539 | 535 | |
| pharynx | 3 / 41328 | 72 | |
| pituitary gland | 1 / 16585 | 60 | |
| placenta | 22 / 280825 | 78 | |
| prostate | 16 / 189345 | 84 | |
| salivary gland | 2 / 20155 | 99 | |
| skin | 56 / 210574 | 265 | |
| spleen | 4 / 53952 | 74 | |
| stomach | 32 / 96619 | 331 | |
| testis | 85 / 330442 | 257 | |
| thymus | 2 / 81131 | 24 | |
| thyroid | 7 / 47473 | 147 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 0 / 52413 | 0 | |
| umbilical cord | 4 / 13680 | 292 | |
| uterus | 72 / 232878 | 309 | |
| vascular | 3 / 51780 | 57 |
- Microarray Platform: GeneAtlas U133A, gcrma
- Affymatrix Probe ID: 208767_s_at
| Cell line | Expression level | Expression bar |
|---|---|---|
![]() | ||
| 721_B_lymphoblasts | 8.6 | |
| Adipocyte | 73.8 | |
| AdrenalCortex | 55.95 | |
| Adrenalgland | 113.4 | |
| Amygdala | 117.15 | |
| Appendix | 18.7 | |
| AtrioventricularNode | 29.25 | |
| BDCA4+_DentriticCells | 6.35 | |
| Bonemarrow | 46.1 | |
| BronchialEpithelialCells | 301.5 | |
| CD105+_Endothelial | 7.2 | |
| CD14+_Monocytes | 12.65 | |
| CD19+_BCells(neg._sel.) | 6.85 | |
| CD33+_Myeloid | 9.35 | |
| CD34+ | 159.3 | |
| CD4+_Tcells | 8.9 | |
| CD56+_NKCells | 7.9 | |
| CD71+_EarlyErythroid | 7.6 | |
| CD8+_Tcells | 7.05 | |
| CardiacMyocytes | 161.65 | |
| Caudatenucleus | 48.15 | |
| Cerebellum | 59.65 | |
| CerebellumPeduncles | 72.75 | |
| CiliaryGanglion | 13.5 | |
| CingulateCortex | 49.1 | |
| Colorectaladenocarcinoma | 181.7 | |
| DorsalRootGanglion | 24.6 | |
| FetalThyroid | 41.35 | |
| Fetalbrain | 34.65 | |
| Fetalliver | 142.5 | |
| Fetallung | 101.6 | |
| GlobusPallidus | 25.8 | |
| Heart | 240.2 | |
| Hypothalamus | 145.35 | |
| Kidney | 106.8 | |
| Leukemia_chronicMyelogenousK-562 | 954.65 | |
| Leukemia_promyelocytic-HL-60 | 7.05 | |
| Leukemialymphoblastic(MOLT-4) | 54.6 | |
| Liver | 89.65 | |
| Lung | 216.05 | |
| Lymphnode | 42.7 | |
| Lymphoma_burkitts(Daudi) | 14.25 | |
| Lymphoma_burkitts(Raji) | 21.85 | |
| MedullaOblongata | 54.15 | |
| OccipitalLobe | 59.95 | |
| OlfactoryBulb | 43.15 | |
| Ovary | 86.35 | |
| Pancreas | 158.4 | |
| PancreaticIslet | 333.35 | |
| ParietalLobe | 66.05 | |
| Pituitary | 100.95 | |
| Placenta | 68.3 | |
| Pons | 45.1 | |
| PrefrontalCortex | 74.35 | |
| Prostate | 77.05 | |
| Salivarygland | 93 | |
| SkeletalMuscle | 26.55 | |
| Skin | 39.2 | |
| SmoothMuscle | 156.65 | |
| Spinalcord | 131.1 | |
| SubthalamicNucleus | 20 | |
| SuperiorCervicalGanglion | 76.5 | |
| TemporalLobe | 52.9 | |
| Testis | 206.6 | |
| TestisGermCell | 315.85 | |
| TestisIntersitial | 71.3 | |
| TestisLeydigCell | 104.9 | |
| TestisSeminiferousTubule | 85.3 | |
| Thalamus | 103.1 | |
| Thymus | 23 | |
| Thyroid | 272.2 | |
| Tongue | 18.25 | |
| Tonsil | 25.05 | |
| Trachea | 110.6 | |
| TrigeminalGanglion | 43.75 | |
| Uterus | 85.8 | |
| UterusCorpus | 123.9 | |
| WholeBlood | 16.3 | |
| Wholebrain | 200.15 | |
| colon | 173.25 | |
| pineal_day | 1464.38 | |
| pineal_night | 990.6 | |
| retina | 818.3 | |
| small_intestine | 382.85 |
- Probe name: A_24_P414999
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 5.49 ± 0.91 | |
| Basal Forebrain | 5.85 ± 0.41 | |
| Basal Part of Pons | 6.08 ± 0.42 | |
| Cerebellar Cortex | 5.99 ± 0.54 | |
| Cerebellar Nuclei | 6.37 ± 0.67 | |
| Claustrum | 5.02 ± 1.01 | |
| Epithalamus | 6.51 ± 0.73 | |
| Frontal Lobe | 6.18 ± 0.57 | |
| Globus Pallidus | 6.67 ± 0.33 | |
| Hypothalamus | 6.35 ± 0.93 | |
| Insula | 5.93 ± 0.43 | |
| Limbic Lobe | 5.32 ± 0.64 | |
| Mesencephalon | 6.16 ± 0.67 | |
| Myelencephalon | 5.96 ± 0.69 | |
| Occipital Lobe | 5.97 ± 0.56 | |
| Parietal Lobe | 6.21 ± 0.74 | |
| Pontine Tegmentum | 6.17 ± 0.58 | |
| Striatum | 5.32 ± 0.54 | |
| Subthalamus | 6.25 ± 0.54 | |
| Temporal Lobe | 5.9 ± 0.58 | |
| Thalamus | 6.39 ± 0.54 | |
| White Matter | 6.47 ± 0.17 |
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Laptm4b | CB | Cerebellum | 33.06 | |
| 99.8 | ||||
| Laptm4b | CTX | Cerebral cortex | 63.22 | |
| 59.27 | ||||
| Laptm4b | HIP | Hippocampal region | 32.74 | |
| 58.91 | ||||
| Laptm4b | HPF | Hippocampal formation | 39.63 | |
| 50.79 | ||||
| Laptm4b | HY | Hypothalamus | 27.93 | |
| 18.18 | ||||
| Laptm4b | LSX | Lateral septal complex | 62.48 | |
| 55.45 | ||||
| Laptm4b | MB | Midbrain | 44.32 | |
| 43.31 | ||||
| Laptm4b | MY | Medulla | 50.98 | |
| 64.69 | ||||
| Laptm4b | OLF | Olfactory bulb | 66.22 | |
| 64.35 | ||||
| Laptm4b | P | Pons | 45.31 | |
| 52.25 | ||||
| Laptm4b | PAL | Pallidum | 33.24 | |
| 30.27 | ||||
| Laptm4b | RHP | Retrohippocampal region | 47.58 | |
| 40.85 | ||||
| Laptm4b | sAMY | Striatum-like amygdalar nuclei | 30.22 | |
| 19.49 | ||||
| Laptm4b | STR | Striatum | 18.49 | |
| 14.35 | ||||
| Laptm4b | STRd | Striatum dorsal region | 12.67 | |
| 10.11 | ||||
| Laptm4b | STRv | Striatum ventral region | 14.98 | |
| 10.82 | ||||
| Laptm4b | TH | Thalamus | 37.09 | |
| 32.29 |




Peptide