AutismKB 2.0

Annotation Detail for STYK1


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Basic Information Top
Gene Symbol:STYK1 ( DKFZp761P1010,NOK,SuRTK106 )
Gene Full Name: serine/threonine/tyrosine kinase 1
Band: 12p13.2
Quick LinksEntrez ID:55359; OMIM: 611433; Uniprot ID:STYK1_HUMAN; ENSEMBL ID: ENSG00000060140; HGNC ID: 18889
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst0 / 623190 
fetus0 / 5640120 
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult18 / 19391219
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor0 / 2638450 
glioma0 / 1068830 
head and neck tumor6 / 13630244
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal29 / 33603078
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer3 / 10268029
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood1 / 1234788
bone0 / 716550 
bone marrow0 / 488010 
brain16 / 110098914
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue1 / 2157224
esophagus0 / 202090 
eye0 / 2110540 
heart0 / 896260 
intestine3 / 23447212
kidney0 / 2117770 
larynx0 / 241450 
liver0 / 2077430 
lung1 / 3369742
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth7 / 67052104
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland1 / 1658560
placenta0 / 2808250 
prostate4 / 18934521
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach0 / 966190 
testis0 / 3304420 
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus1 / 2328784
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 221696_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts7.65
Adipocyte9.3
AdrenalCortex11.7
Adrenalgland8.95
Amygdala10.9
Appendix16
AtrioventricularNode12.65
BDCA4+_DentriticCells6.4
Bonemarrow11.7
BronchialEpithelialCells7.85
CD105+_Endothelial9.45
CD14+_Monocytes10.05
CD19+_BCells(neg._sel.)9.45
CD33+_Myeloid10.75
CD34+10.5
CD4+_Tcells8.15
CD56+_NKCells10.2
CD71+_EarlyErythroid9.15
CD8+_Tcells7
CardiacMyocytes15.55
Caudatenucleus8.6
Cerebellum7.9
CerebellumPeduncles15.45
CiliaryGanglion8.25
CingulateCortex10.1
Colorectaladenocarcinoma9.4
DorsalRootGanglion8.35
FetalThyroid12.5
Fetalbrain9.1
Fetalliver8.8
Fetallung6.5
GlobusPallidus7.6
Heart19.55
Hypothalamus9.65
Kidney9.75
Leukemia_chronicMyelogenousK-5628.55
Leukemia_promyelocytic-HL-608.45
Leukemialymphoblastic(MOLT-4)6.8
Liver14.4
Lung10.2
Lymphnode7.8
Lymphoma_burkitts(Daudi)12.55
Lymphoma_burkitts(Raji)14.55
MedullaOblongata12.75
OccipitalLobe8.5
OlfactoryBulb7.5
Ovary7.4
Pancreas10
PancreaticIslet10.15
ParietalLobe11.3
Pituitary14.35
Placenta9.15
Pons16.6
PrefrontalCortex10.75
Prostate11.5
Salivarygland8.7
SkeletalMuscle13.1
Skin8.55
SmoothMuscle10.65
Spinalcord10.25
SubthalamicNucleus9.25
SuperiorCervicalGanglion13.45
TemporalLobe10.45
Testis8.15
TestisGermCell7.35
TestisIntersitial8.5
TestisLeydigCell10.6
TestisSeminiferousTubule8.2
Thalamus9.95
Thymus6.7
Thyroid11.25
Tongue13.7
Tonsil9.5
Trachea8.95
TrigeminalGanglion12.8
Uterus7.5
UterusCorpus12.8
WholeBlood8.6
Wholebrain7.3
colon12.45
pineal_day9.88
pineal_night9.82
retina11.475
small_intestine9.2
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_10118_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.09 ± 0.91
Basal Forebrain3.42 ± 0.28
Basal Part of Pons4.07 ± 0.61
Cerebellar Cortex3.24 ± 0.45
Cerebellar Nuclei3.89 ± 0.61
Claustrum4.23 ± 0.89
Epithalamus3.35 ± 0.97
Frontal Lobe4.26 ± 0.59
Globus Pallidus2.84 ± 1.36
Hypothalamus3.94 ± 0.78
Insula4.41 ± 0.23
Limbic Lobe4.16 ± 0.7
Mesencephalon4.15 ± 0.83
Myelencephalon4.02 ± 0.7
Occipital Lobe3.23 ± 1.06
Parietal Lobe4.01 ± 0.71
Pontine Tegmentum3.88 ± 0.78
Striatum3.74 ± 1.19
Subthalamus3.77 ± 0.83
Temporal Lobe4.44 ± 0.66
Thalamus3.71 ± 0.76
White Matter2.21 ± 0.94
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Styk1CBCerebellum2.8
3.61
Styk1CTXCerebral cortex1.56
1.65
Styk1HIPHippocampal region1.57
1.66
Styk1HPFHippocampal formation1.52
1.6
Styk1HYHypothalamus0.15
0.16
Styk1LSXLateral septal complex2.76
1.92
Styk1MBMidbrain0.4
0.51
Styk1MYMedulla0.72
0.92
Styk1OLFOlfactory bulb1.65
1.52
Styk1PPons0.57
1.01
Styk1PALPallidum0.34
0.31
Styk1RHPRetrohippocampal region1.36
1.04
Styk1sAMYStriatum-like amygdalar nuclei0.36
0.49
Styk1STRStriatum0.55
0.43
Styk1STRdStriatum dorsal region0.43
0.35
Styk1STRvStriatum ventral region0.26
0.22
Styk1THThalamus0.41
0.38
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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