Annotation Detail for PI4K2A
Basic Information Top
| Gene Symbol: | PI4K2A ( DKFZp761G1923,PI4KII,PIK42A,RP11-548K23.6 ) |
|---|---|
| Gene Full Name: | phosphatidylinositol 4-kinase type 2 alpha |
| Band: | 10q24.2 |
| Quick Links | Entrez ID:55361; OMIM: 609763; Uniprot ID:P4K2A_HUMAN; ENSEMBL ID: ENSG00000155252,ENSG00000249967; HGNC ID: 30031 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.25300
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 3 / 70761 | 42 |  |
| blastocyst | 6 / 62319 | 96 |  |
| fetus | 20 / 564012 | 35 | |
| neonate | 1 / 31097 | 32 | |
| infant | 0 / 23620 | 0 | |
| juvenile | 0 / 55556 | 0 | |
| adult | 74 / 1939121 | 38 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 0 / 17475 | 0 | |
| breast (mammary gland) tumor | 0 / 94178 | 0 | |
| cervical tumor | 3 / 34366 | 87 | |
| chondrosarcoma | 8 / 82823 | 96 | |
| colorectal tumor | 1 / 114246 | 8 |  |
| esophageal tumor | 1 / 17290 | 57 | |
| gastrointestinal tumor | 4 / 119369 | 33 | |
| germ cell tumor | 11 / 263845 | 41 | |
| glioma | 5 / 106883 | 46 | |
| head and neck tumor | 5 / 136302 | 36 | |
| kidney tumor | 2 / 68959 | 29 | |
| leukemia | 1 / 95842 | 10 | |
| liver tumor | 1 / 96359 | 10 | |
| lung tumor | 6 / 103127 | 58 | |
| lymphoma | 1 / 71755 | 13 | |
| non-neoplasia | 2 / 97250 | 20 | |
| normal | 123 / 3360307 | 36 | |
| ovarian tumor | 4 / 76682 | 52 | |
| pancreatic tumor | 5 / 104616 | 47 | |
| primitive neuroectodermal tumor of the CNS | 12 / 125680 | 95 | |
| prostate cancer | 2 / 102680 | 19 | |
| retinoblastoma | 1 / 46356 | 21 | |
| skin tumor | 9 / 124949 | 72 | |
| soft tissue/muscle tissue tumor | 2 / 125191 | 15 | |
| uterine tumor | 3 / 90257 | 33 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 0 / 13106 | 0 | |
| adrenal gland | 0 / 33197 | 0 | |
| ascites | 0 / 40015 | 0 | |
| bladder | 2 / 29757 | 67 | |
| blood | 0 / 123478 | 0 | |
| bone | 4 / 71655 | 55 | |
| bone marrow | 0 / 48801 | 0 | |
| brain | 34 / 1100989 | 30 | |
| cervix | 3 / 48171 | 62 | |
| connective tissue | 7 / 149255 | 46 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 10 / 215722 | 46 | |
| esophagus | 1 / 20209 | 49 | |
| eye | 9 / 211054 | 42 | |
| heart | 2 / 89626 | 22 | |
| intestine | 4 / 234472 | 17 | |
| kidney | 5 / 211777 | 23 | |
| larynx | 0 / 24145 | 0 | |
| liver | 2 / 207743 | 9 | |
| lung | 19 / 336974 | 56 | |
| lymph | 0 / 44270 | 0 | |
| lymph node | 1 / 91610 | 10 | |
| mammary gland | 3 / 153271 | 19 | |
| mouth | 1 / 67052 | 14 | |
| muscle | 1 / 107715 | 9 | |
| nerve | 0 / 15768 | 0 | |
| ovary | 5 / 102051 | 48 | |
| pancreas | 5 / 214812 | 23 | |
| parathyroid | 0 / 20539 | 0 | |
| pharynx | 0 / 41328 | 0 | |
| pituitary gland | 1 / 16585 | 60 | |
| placenta | 9 / 280825 | 32 | |
| prostate | 10 / 189345 | 52 | |
| salivary gland | 0 / 20155 | 0 | |
| skin | 11 / 210574 | 52 | |
| spleen | 1 / 53952 | 18 | |
| stomach | 3 / 96619 | 31 | |
| testis | 20 / 330442 | 60 | |
| thymus | 0 / 81131 | 0 | |
| thyroid | 3 / 47473 | 63 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 0 / 52413 | 0 | |
| umbilical cord | 1 / 13680 | 73 | |
| uterus | 13 / 232878 | 55 | |
| vascular | 3 / 51780 | 57 | |
- Microarray Platform: GeneAtlas U133A, gcrma
- Affymatrix Probe ID: 209346_s_at
| Cell line | Expression level | Expression bar |
|---|---|---|
| ||
| 721_B_lymphoblasts | 5.15 | |
| Adipocyte | 4.15 | |
| AdrenalCortex | 4.3 | |
| Adrenalgland | 3.55 | |
| Amygdala | 4.3 | |
| Appendix | 4.25 | |
| AtrioventricularNode | 3.15 | |
| BDCA4+_DentriticCells | 4.7 | |
| Bonemarrow | 4.1 | |
| BronchialEpithelialCells | 4.1 | |
| CD105+_Endothelial | 4.25 | |
| CD14+_Monocytes | 4.35 | |
| CD19+_BCells(neg._sel.) | 4.5 | |
| CD33+_Myeloid | 5.4 | |
| CD34+ | 5.05 | |
| CD4+_Tcells | 4.6 | |
| CD56+_NKCells | 5.6 | |
| CD71+_EarlyErythroid | 5.7 | |
| CD8+_Tcells | 4.05 | |
| CardiacMyocytes | 5.05 | |
| Caudatenucleus | 3.8 | |
| Cerebellum | 3.4 | |
| CerebellumPeduncles | 4.75 | |
| CiliaryGanglion | 2.9 | |
| CingulateCortex | 4.35 | |
| Colorectaladenocarcinoma | 4.15 | |
| DorsalRootGanglion | 3.55 | |
| FetalThyroid | 4.05 | |
| Fetalbrain | 4.2 | |
| Fetalliver | 3.6 | |
| Fetallung | 3.5 | |
| GlobusPallidus | 3.15 | |
| Heart | 5.1 | |
| Hypothalamus | 4.55 | |
| Kidney | 3.45 | |
| Leukemia_chronicMyelogenousK-562 | 3.8 | |
| Leukemia_promyelocytic-HL-60 | 3.7 | |
| Leukemialymphoblastic(MOLT-4) | 3.35 | |
| Liver | 5.45 | |
| Lung | 4.65 | |
| Lymphnode | 3.65 | |
| Lymphoma_burkitts(Daudi) | 5.3 | |
| Lymphoma_burkitts(Raji) | 5.65 | |
| MedullaOblongata | 3.95 | |
| OccipitalLobe | 3.8 | |
| OlfactoryBulb | 3.35 | |
| Ovary | 2.75 | |
| Pancreas | 3.35 | |
| PancreaticIslet | 4.45 | |
| ParietalLobe | 4.45 | |
| Pituitary | 4.9 | |
| Placenta | 4.4 | |
| Pons | 6.3 | |
| PrefrontalCortex | 5.3 | |
| Prostate | 4.85 | |
| Salivarygland | 3.3 | |
| SkeletalMuscle | 4.65 | |
| Skin | 3.2 | |
| SmoothMuscle | 4.7 | |
| Spinalcord | 4.45 | |
| SubthalamicNucleus | 3.85 | |
| SuperiorCervicalGanglion | 4.7 | |
| TemporalLobe | 4.4 | |
| Testis | 3.6 | |
| TestisGermCell | 3.5 | |
| TestisIntersitial | 3.5 | |
| TestisLeydigCell | 4.1 | |
| TestisSeminiferousTubule | 3.6 | |
| Thalamus | 4.25 | |
| Thymus | 3.15 | |
| Thyroid | 5.25 | |
| Tongue | 4.05 | |
| Tonsil | 4.1 | |
| Trachea | 3.5 | |
| TrigeminalGanglion | 4.1 | |
| Uterus | 3.4 | |
| UterusCorpus | 3.55 | |
| WholeBlood | 4.35 | |
| Wholebrain | 3.55 | |
| colon | 4.2 | |
| pineal_day | 5.18 | |
| pineal_night | 5.04 | |
| retina | 5.15 | |
| small_intestine | 4.05 | |
- Probe name: A_23_P127339
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 8.81 ± 0.3 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 9 ± 0.24 | |
| Basal Part of Pons | 9.33 ± 0.2 | |
| Cerebellar Cortex | 9.22 ± 0.28 | |
| Cerebellar Nuclei | 9.26 ± 0.4 | |
| Claustrum | 9.13 ± 0.49 | |
| Epithalamus | 8.33 ± 0.35 | |
| Frontal Lobe | 8.9 ± 0.34 | |
| Globus Pallidus | 9.13 ± 0.34 | |
| Hypothalamus | 8.74 ± 0.34 | |
| Insula | 8.75 ± 0.4 | |
| Limbic Lobe | 9.07 ± 0.45 | |
| Mesencephalon | 9.06 ± 0.41 | |
| Myelencephalon | 8.99 ± 0.37 | |
| Occipital Lobe | 9.38 ± 0.36 | |
| Parietal Lobe | 9.06 ± 0.3 | |
| Pontine Tegmentum | 8.93 ± 0.29 | |
| Striatum | 9.03 ± 0.34 | |
| Subthalamus | 9.07 ± 0.15 | |
| Temporal Lobe | 8.88 ± 0.29 | |
| Thalamus | 9.06 ± 0.28 | |
| White Matter | 8.3 ± 0.12 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Pi4k2a | CB | Cerebellum | 22.55 | |
| 62.23 | | |||
| Pi4k2a | CTX | Cerebral cortex | 77.86 | |
| 54.97 | | |||
| Pi4k2a | HIP | Hippocampal region | 44.7 | |
| 71.93 | | |||
| Pi4k2a | HPF | Hippocampal formation | 51.96 | |
| 59.53 | | |||
| Pi4k2a | HY | Hypothalamus | 31.37 | |
| 21.13 | | |||
| Pi4k2a | LSX | Lateral septal complex | 13.91 | |
| 8.74 | | |||
| Pi4k2a | MB | Midbrain | 42.24 | |
| 37.58 | | |||
| Pi4k2a | MY | Medulla | 45.34 | |
| 53.28 | | |||
| Pi4k2a | OLF | Olfactory bulb | 67.29 | |
| 53.02 | | |||
| Pi4k2a | P | Pons | 53.82 | |
| 57.64 | | |||
| Pi4k2a | PAL | Pallidum | 38.88 | |
| 32.39 | | |||
| Pi4k2a | RHP | Retrohippocampal region | 65.84 | |
| 48.2 | | |||
| Pi4k2a | sAMY | Striatum-like amygdalar nuclei | 40.29 | |
| 21.6 | | |||
| Pi4k2a | STR | Striatum | 32.44 | |
| 17.68 | | |||
| Pi4k2a | STRd | Striatum dorsal region | 22.57 | |
| 12.14 | | |||
| Pi4k2a | STRv | Striatum ventral region | 31.03 | |
| 17.21 | | |||
| Pi4k2a | TH | Thalamus | 60.59 | |
| 51.38 | |
| Peptide Name | Peptide Lengh | Peptide Start | Peptide End | Peptide Sequence | Source |
|---|---|---|---|---|---|
| PAp00132613 | 19 | 38 | 56 | VAAAAGSGPSPPGSPGHDR | Peptide Atlas |