AutismKB 2.0

Annotation Detail for PRCP


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Basic Information Top
Gene Symbol:PRCP ( HUMPCP,MGC2202,PCP )
Gene Full Name: prolylcarboxypeptidase (angiotensinase C)
Band: 11q14
Quick LinksEntrez ID:5547; OMIM: 176785; Uniprot ID:PCP_HUMAN; ENSEMBL ID: ENSG00000137509; HGNC ID: 9344
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body6 / 7076184
blastocyst8 / 62319128
fetus54 / 56401295
neonate6 / 31097192
infant0 / 236200 
juvenile8 / 55556143
adult241 / 1939121124
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor4 / 12794312
bladder carcinoma0 / 174750 
breast (mammary gland) tumor8 / 9417884
cervical tumor4 / 34366116
chondrosarcoma9 / 82823108
colorectal tumor5 / 11424643
esophageal tumor5 / 17290289
gastrointestinal tumor17 / 119369142
germ cell tumor11 / 26384541
glioma12 / 106883112
head and neck tumor16 / 136302117
kidney tumor5 / 6895972
leukemia12 / 95842125
liver tumor7 / 9635972
lung tumor5 / 10312748
lymphoma9 / 71755125
non-neoplasia7 / 9725071
normal393 / 3360307116
ovarian tumor5 / 7668265
pancreatic tumor7 / 10461666
primitive neuroectodermal tumor of the CNS13 / 125680103
prostate cancer14 / 102680136
retinoblastoma2 / 4635643
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor5 / 12519139
uterine tumor15 / 90257166
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland6 / 33197180
ascites8 / 40015199
bladder0 / 297570 
blood8 / 12347864
bone7 / 7165597
bone marrow3 / 4880161
brain63 / 110098957
cervix4 / 4817183
connective tissue9 / 14925560
ear3 / 16212185
embryonic tissue26 / 215722120
esophagus6 / 20209296
eye10 / 21105447
heart26 / 89626290
intestine10 / 23447242
kidney22 / 211777103
larynx0 / 241450 
liver32 / 207743154
lung27 / 33697480
lymph1 / 4427022
lymph node7 / 9161076
mammary gland12 / 15327178
mouth6 / 6705289
muscle3 / 10771527
nerve0 / 157680 
ovary10 / 10205197
pancreas12 / 21481255
parathyroid3 / 20539146
pharynx11 / 41328266
pituitary gland1 / 1658560
placenta82 / 280825291
prostate21 / 189345110
salivary gland1 / 2015549
skin4 / 21057418
spleen2 / 5395237
stomach10 / 96619103
testis45 / 330442136
thymus7 / 8113186
thyroid8 / 47473168
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord6 / 13680438
uterus35 / 232878150
vascular12 / 51780231
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 201494_at
Cell line Expression level Expression bar
721_B_lymphoblasts222.5
Adipocyte292.5
AdrenalCortex233.15
Adrenalgland216.55
Amygdala209.05
Appendix156.5
AtrioventricularNode130
BDCA4+_DentriticCells658.2
Bonemarrow177.25
BronchialEpithelialCells178.9
CD105+_Endothelial157.5
CD14+_Monocytes830.85
CD19+_BCells(neg._sel.)488.75
CD33+_Myeloid862.25
CD34+206.05
CD4+_Tcells142.05
CD56+_NKCells303.75
CD71+_EarlyErythroid91.55
CD8+_Tcells114.15
CardiacMyocytes335.15
Caudatenucleus127.95
Cerebellum139.1
CerebellumPeduncles166.55
CiliaryGanglion136.35
CingulateCortex140.75
Colorectaladenocarcinoma176.15
DorsalRootGanglion180.6
FetalThyroid344.1
Fetalbrain107.1
Fetalliver177
Fetallung444.45
GlobusPallidus110.9
Heart141.55
Hypothalamus349.4
Kidney275
Leukemia_chronicMyelogenousK-562167.3
Leukemia_promyelocytic-HL-60159.55
Leukemialymphoblastic(MOLT-4)58.3
Liver243.65
Lung320.45
Lymphnode474.6
Lymphoma_burkitts(Daudi)193.8
Lymphoma_burkitts(Raji)305.8
MedullaOblongata118.05
OccipitalLobe105.3
OlfactoryBulb337.5
Ovary108.05
Pancreas81.45
PancreaticIslet217.7
ParietalLobe66.9
Pituitary274.1
Placenta564.75
Pons145.85
PrefrontalCortex228.15
Prostate253.15
Salivarygland233.85
SkeletalMuscle95.7
Skin119.45
SmoothMuscle305.05
Spinalcord374.25
SubthalamicNucleus121.1
SuperiorCervicalGanglion179.1
TemporalLobe91.4
Testis176.95
TestisGermCell237.15
TestisIntersitial345.75
TestisLeydigCell214.9
TestisSeminiferousTubule159.2
Thalamus226.95
Thymus125.85
Thyroid393.45
Tongue132.4
Tonsil248.1
Trachea167.8
TrigeminalGanglion126.85
Uterus264.7
UterusCorpus186.95
WholeBlood571.05
Wholebrain170.95
colon136.9
pineal_day276.38
pineal_night228.82
retina523.275
small_intestine221.3
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_7781_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.8 ± 0.37
Basal Forebrain4.55 ± 0.24
Basal Part of Pons4.89 ± 0.56
Cerebellar Cortex5.18 ± 0.32
Cerebellar Nuclei4.97 ± 0.57
Claustrum4.33 ± 0.71
Epithalamus6.06 ± 0.44
Frontal Lobe5 ± 0.55
Globus Pallidus5.54 ± 0.44
Hypothalamus5.14 ± 0.57
Insula4.81 ± 0.4
Limbic Lobe4.66 ± 0.51
Mesencephalon5.02 ± 0.36
Myelencephalon4.91 ± 0.56
Occipital Lobe4.95 ± 0.4
Parietal Lobe5.01 ± 0.44
Pontine Tegmentum4.93 ± 0.62
Striatum4.5 ± 0.55
Subthalamus5.12 ± 0.18
Temporal Lobe4.85 ± 0.43
Thalamus5.08 ± 0.45
White Matter3.69 ± 1.21
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
PrcpCBCerebellum1.5
3.19
PrcpCTXCerebral cortex4.38
3.93
PrcpHIPHippocampal region3.99
5.02
PrcpHPFHippocampal formation3.94
4.41
PrcpHYHypothalamus1.17
1.07
PrcpLSXLateral septal complex0.12
0.08
PrcpMBMidbrain1.25
1.75
PrcpMYMedulla4.24
5.49
PrcpOLFOlfactory bulb4.3
3.13
PrcpPPons6.91
9.5
PrcpPALPallidum0.29
0.37
PrcpRHPRetrohippocampal region3.98
3.74
PrcpsAMYStriatum-like amygdalar nuclei1
1.19
PrcpSTRStriatum0.36
0.44
PrcpSTRdStriatum dorsal region0.17
0.32
PrcpSTRvStriatum ventral region0.79
0.65
PrcpTHThalamus1.22
1.21
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00011449 11 229 239 SGPHCSESIHR Peptide Atlas
PCP_HUMAN_0 0 0 0 DITDTLVAVTISEGAHHLDLR PRIDE
PCP_HUMAN_115 9 115 123 AMLVFAEHR PRIDE
PCP_HUMAN_140 19 140 158 HLNFLTSEQALADFAELIK PRIDE
PCP_HUMAN_439 21 439 459 DITDTLVAVTISEGAHHLDLR PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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