AutismKB 2.0

Annotation Detail for PRELP


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Basic Information Top
Gene Symbol:PRELP ( MGC45323,MST161,MSTP161,SLRR2A )
Gene Full Name: proline/arginine-rich end leucine-rich repeat protein
Band: 1q32.1
Quick LinksEntrez ID:5549; OMIM: 601914; Uniprot ID:PRELP_HUMAN; ENSEMBL ID: ENSG00000188783; HGNC ID: 9357
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus36 / 56401263
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult226 / 1939121116
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor8 / 12794625
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma28 / 82823338
colorectal tumor0 / 1142460 
esophageal tumor1 / 1729057
gastrointestinal tumor2 / 11936916
germ cell tumor1 / 2638453
glioma4 / 10688337
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor1 / 1031279
lymphoma0 / 717550 
non-neoplasia131 / 972501347
normal210 / 336030762
ovarian tumor2 / 7668226
pancreatic tumor10 / 10461695
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer2 / 10268019
retinoblastoma0 / 463560 
skin tumor2 / 12494916
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland8 / 33197240
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone11 / 71655153
bone marrow0 / 488010 
brain33 / 110098929
cervix0 / 481710 
connective tissue171 / 1492551145
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus1 / 2020949
eye40 / 211054189
heart6 / 8962666
intestine3 / 23447212
kidney5 / 21177723
larynx0 / 241450 
liver2 / 2077439
lung13 / 33697438
lymph0 / 442700 
lymph node0 / 916100 
mammary gland8 / 15327152
mouth0 / 670520 
muscle5 / 10771546
nerve0 / 157680 
ovary5 / 10205148
pancreas17 / 21481279
parathyroid1 / 2053948
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta7 / 28082524
prostate15 / 18934579
salivary gland0 / 201550 
skin11 / 21057452
spleen5 / 5395292
stomach3 / 9661931
testis4 / 33044212
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus8 / 23287834
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 204223_at
Cell line Expression level Expression bar
721_B_lymphoblasts8.05
Adipocyte56.5
AdrenalCortex22.25
Adrenalgland28.35
Amygdala17.45
Appendix100.65
AtrioventricularNode82
BDCA4+_DentriticCells9.2
Bonemarrow15.3
BronchialEpithelialCells12.2
CD105+_Endothelial9.9
CD14+_Monocytes6.55
CD19+_BCells(neg._sel.)9.1
CD33+_Myeloid13.2
CD34+9.95
CD4+_Tcells7.65
CD56+_NKCells8.4
CD71+_EarlyErythroid10.8
CD8+_Tcells6.65
CardiacMyocytes17.95
Caudatenucleus20.95
Cerebellum13
CerebellumPeduncles16.35
CiliaryGanglion73.25
CingulateCortex16.75
Colorectaladenocarcinoma11.75
DorsalRootGanglion61.95
FetalThyroid16
Fetalbrain12.5
Fetalliver11.9
Fetallung14.1
GlobusPallidus9.9
Heart113.2
Hypothalamus18.45
Kidney23.35
Leukemia_chronicMyelogenousK-56212.3
Leukemia_promyelocytic-HL-6012
Leukemialymphoblastic(MOLT-4)9.6
Liver29.75
Lung461
Lymphnode19.9
Lymphoma_burkitts(Daudi)17.1
Lymphoma_burkitts(Raji)20.7
MedullaOblongata13.55
OccipitalLobe11.2
OlfactoryBulb137.75
Ovary94.35
Pancreas14.05
PancreaticIslet18.8
ParietalLobe16.3
Pituitary33.9
Placenta29
Pons18.8
PrefrontalCortex21.6
Prostate58.45
Salivarygland30.75
SkeletalMuscle20.45
Skin12.85
SmoothMuscle14.2
Spinalcord46.6
SubthalamicNucleus11.25
SuperiorCervicalGanglion72.9
TemporalLobe13.7
Testis21.2
TestisGermCell26.3
TestisIntersitial12.4
TestisLeydigCell15.35
TestisSeminiferousTubule11.75
Thalamus15.05
Thymus15.3
Thyroid41.1
Tongue50
Tonsil15.25
Trachea144.75
TrigeminalGanglion87.05
Uterus173.25
UterusCorpus72.75
WholeBlood12.75
Wholebrain14.15
colon27.65
pineal_day16.26
pineal_night17.32
retina195.575
small_intestine23.45
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P51499
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.62 ± 0.36
Basal Forebrain4.35 ± 0.36
Basal Part of Pons4.24 ± 0.47
Cerebellar Cortex4.05 ± 0.39
Cerebellar Nuclei5.19 ± 0.44
Claustrum3.82 ± 0.61
Epithalamus4.56 ± 0.73
Frontal Lobe4.53 ± 0.64
Globus Pallidus4.84 ± 0.39
Hypothalamus3.76 ± 0.48
Insula4.47 ± 0.41
Limbic Lobe4.41 ± 0.64
Mesencephalon4.42 ± 0.66
Myelencephalon4.52 ± 0.63
Occipital Lobe4.37 ± 0.59
Parietal Lobe4.32 ± 0.56
Pontine Tegmentum4.66 ± 0.62
Striatum5.5 ± 0.4
Subthalamus4.91 ± 0.25
Temporal Lobe4.46 ± 0.53
Thalamus4.66 ± 0.6
White Matter3.55 ± 1.04
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
PrelpCBCerebellum33.73
51.68
PrelpCTXCerebral cortex42.49
33.72
PrelpHIPHippocampal region22.51
24.46
PrelpHPFHippocampal formation29.7
28.81
PrelpHYHypothalamus21.67
20.2
PrelpLSXLateral septal complex29.89
42.62
PrelpMBMidbrain18.69
22.67
PrelpMYMedulla48.75
58.89
PrelpOLFOlfactory bulb53.95
46.23
PrelpPPons33.59
43.27
PrelpPALPallidum14.32
13.99
PrelpRHPRetrohippocampal region46.22
37.13
PrelpsAMYStriatum-like amygdalar nuclei15.67
13.27
PrelpSTRStriatum17.94
16.22
PrelpSTRdStriatum dorsal region17.04
14.83
PrelpSTRvStriatum ventral region16.86
11.76
PrelpTHThalamus25.9
28.7
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00377100 17 76 92 ECYCPPDFPSALYCDSR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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