AutismKB 2.0

Annotation Detail for NOP10


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Basic Information Top
Gene Symbol:NOP10 ( MGC70651,NOLA3,NOP10P )
Gene Full Name: NOP10 ribonucleoprotein homolog (yeast)
Band: 15q14
Quick LinksEntrez ID:55505; OMIM: 606471; Uniprot ID:NOP10_HUMAN; ENSEMBL ID: ENSG00000182117; HGNC ID: 14378
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body3 / 7076142
blastocyst6 / 6231996
fetus69 / 564012122
neonate3 / 3109796
infant1 / 2362042
juvenile1 / 5555617
adult89 / 193912145
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor6 / 12794468
bladder carcinoma3 / 17475171
breast (mammary gland) tumor4 / 9417842
cervical tumor0 / 343660 
chondrosarcoma4 / 8282348
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor9 / 11936975
germ cell tumor4 / 26384515
glioma21 / 106883196
head and neck tumor2 / 13630214
kidney tumor6 / 6895987
leukemia8 / 9584283
liver tumor2 / 9635920
lung tumor6 / 10312758
lymphoma1 / 7175513
non-neoplasia2 / 9725020
normal240 / 336030771
ovarian tumor2 / 7668226
pancreatic tumor9 / 10461686
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer11 / 102680107
retinoblastoma0 / 463560 
skin tumor10 / 12494980
soft tissue/muscle tissue tumor6 / 12519147
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland8 / 33197240
ascites1 / 4001524
bladder3 / 29757100
blood22 / 123478178
bone2 / 7165527
bone marrow13 / 48801266
brain40 / 110098936
cervix0 / 481710 
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue10 / 21572246
esophagus0 / 202090 
eye6 / 21105428
heart24 / 89626267
intestine6 / 23447225
kidney11 / 21177751
larynx1 / 2414541
liver4 / 20774319
lung17 / 33697450
lymph0 / 442700 
lymph node10 / 91610109
mammary gland5 / 15327132
mouth2 / 6705229
muscle5 / 10771546
nerve0 / 157680 
ovary2 / 10205119
pancreas10 / 21481246
parathyroid3 / 20539146
pharynx1 / 4132824
pituitary gland2 / 16585120
placenta6 / 28082521
prostate16 / 18934584
salivary gland1 / 2015549
skin26 / 210574123
spleen1 / 5395218
stomach8 / 9661982
testis9 / 33044227
thymus0 / 811310 
thyroid1 / 4747321
tonsil1 / 1699958
trachea0 / 524130 
umbilical cord3 / 13680219
uterus19 / 23287881
vascular4 / 5178077
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 217962_at
Cell line Expression level Expression bar
721_B_lymphoblasts1586.7
Adipocyte555.2
AdrenalCortex148.5
Adrenalgland374.4
Amygdala144.95
Appendix133.35
AtrioventricularNode42.75
BDCA4+_DentriticCells876.85
Bonemarrow615.75
BronchialEpithelialCells1751.45
CD105+_Endothelial1244.35
CD14+_Monocytes1097.05
CD19+_BCells(neg._sel.)632.3
CD33+_Myeloid845.05
CD34+866.35
CD4+_Tcells490.6
CD56+_NKCells606
CD71+_EarlyErythroid523.55
CD8+_Tcells411.4
CardiacMyocytes606.65
Caudatenucleus139.7
Cerebellum177.35
CerebellumPeduncles249.75
CiliaryGanglion75.05
CingulateCortex109.55
Colorectaladenocarcinoma113.45
DorsalRootGanglion94.3
FetalThyroid379.3
Fetalbrain275.85
Fetalliver349.75
Fetallung433.9
GlobusPallidus71.95
Heart633.9
Hypothalamus202.3
Kidney302.15
Leukemia_chronicMyelogenousK-562566.95
Leukemia_promyelocytic-HL-60878.4
Leukemialymphoblastic(MOLT-4)544.75
Liver357.25
Lung588.25
Lymphnode329.15
Lymphoma_burkitts(Daudi)595.15
Lymphoma_burkitts(Raji)438.7
MedullaOblongata106.5
OccipitalLobe193.55
OlfactoryBulb196.15
Ovary67.55
Pancreas162.65
PancreaticIslet337.8
ParietalLobe137.6
Pituitary311.65
Placenta381.4
Pons94.95
PrefrontalCortex185.45
Prostate311.7
Salivarygland194.4
SkeletalMuscle198.2
Skin95.85
SmoothMuscle1240
Spinalcord197.95
SubthalamicNucleus91.2
SuperiorCervicalGanglion64.6
TemporalLobe130.85
Testis199.9
TestisGermCell212.55
TestisIntersitial109.55
TestisLeydigCell89.75
TestisSeminiferousTubule95.8
Thalamus202.45
Thymus621.5
Thyroid259.9
Tongue242.1
Tonsil441.05
Trachea218.95
TrigeminalGanglion97.8
Uterus201.6
UterusCorpus434.4
WholeBlood1676.05
Wholebrain329.3
colon454.6
pineal_day255.2
pineal_night261.24
retina282.25
small_intestine493.6
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_11978_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.35 ± 0.38
Basal Forebrain7.38 ± 0.31
Basal Part of Pons7.8 ± 0.31
Cerebellar Cortex7.63 ± 0.35
Cerebellar Nuclei7.72 ± 0.37
Claustrum7.29 ± 0.51
Epithalamus7.52 ± 0.42
Frontal Lobe7.75 ± 0.33
Globus Pallidus7.11 ± 0.27
Hypothalamus7.9 ± 0.23
Insula7.78 ± 0.3
Limbic Lobe7.38 ± 0.53
Mesencephalon7.38 ± 0.46
Myelencephalon7.45 ± 0.51
Occipital Lobe7 ± 0.47
Parietal Lobe7.5 ± 0.38
Pontine Tegmentum7.55 ± 0.42
Striatum7.17 ± 0.43
Subthalamus7.61 ± 0.4
Temporal Lobe7.7 ± 0.42
Thalamus7.43 ± 0.36
White Matter6.76 ± 0.28
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Nola3CBCerebellum3.22
3.81
Nola3CTXCerebral cortex1.45
1.12
Nola3HIPHippocampal region2.43
2.43
Nola3HPFHippocampal formation1.63
1.49
Nola3HYHypothalamus0.93
0.94
Nola3LSXLateral septal complex0.17
0.25
Nola3MBMidbrain1.27
1.33
Nola3MYMedulla6.64
7.1
Nola3OLFOlfactory bulb1.45
1.34
Nola3PPons3.65
3.48
Nola3PALPallidum1.21
0.95
Nola3RHPRetrohippocampal region0.46
0.32
Nola3sAMYStriatum-like amygdalar nuclei0.57
0.21
Nola3STRStriatum0.95
1.01
Nola3STRdStriatum dorsal region1.27
1.34
Nola3STRvStriatum ventral region0.51
0.79
Nola3THThalamus0.64
0.54
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
NOP10_HUMAN_1 13 1 13 MFLQYYLNEQGDR PRIDE
PAp00004269 16 19 34 KFDPMGQQTCSAHPAR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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