AutismKB 2.0

Annotation Detail for H2AFY2


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:H2AFY2 ( macroH2A2 )
Gene Full Name: H2A histone family, member Y2
Band: 10q22.1
Quick LinksEntrez ID:55506; OMIM: NA; Uniprot ID:H2AW_HUMAN; ENSEMBL ID: ENSG00000099284; HGNC ID: 14453
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body8 / 70761113
blastocyst10 / 62319160
fetus55 / 56401297
neonate0 / 310970 
infant2 / 2362084
juvenile3 / 5555653
adult77 / 193912139
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor4 / 9417842
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor9 / 11424678
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor17 / 26384564
glioma11 / 106883102
head and neck tumor2 / 13630214
kidney tumor4 / 6895958
leukemia0 / 958420 
liver tumor9 / 9635993
lung tumor4 / 10312738
lymphoma0 / 717550 
non-neoplasia4 / 9725041
normal177 / 336030752
ovarian tumor16 / 76682208
pancreatic tumor4 / 10461638
primitive neuroectodermal tumor of the CNS22 / 125680175
prostate cancer2 / 10268019
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor10 / 12519179
uterine tumor3 / 9025733
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland2 / 3319760
ascites0 / 400150 
bladder2 / 2975767
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain54 / 110098949
cervix0 / 481710 
connective tissue3 / 14925520
ear0 / 162120 
embryonic tissue35 / 215722162
esophagus0 / 202090 
eye19 / 21105490
heart4 / 8962644
intestine13 / 23447255
kidney16 / 21177775
larynx0 / 241450 
liver10 / 20774348
lung20 / 33697459
lymph0 / 442700 
lymph node0 / 916100 
mammary gland6 / 15327139
mouth2 / 6705229
muscle2 / 10771518
nerve1 / 1576863
ovary16 / 102051156
pancreas9 / 21481241
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta3 / 28082510
prostate12 / 18934563
salivary gland0 / 201550 
skin1 / 2105744
spleen0 / 539520 
stomach2 / 9661920
testis11 / 33044233
thymus0 / 811310 
thyroid1 / 4747321
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus11 / 23287847
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 218445_at
Cell line Expression level Expression bar
721_B_lymphoblasts16.95
Adipocyte18.1
AdrenalCortex19.8
Adrenalgland16.45
Amygdala19.45
Appendix20.5
AtrioventricularNode16.6
BDCA4+_DentriticCells12.3
Bonemarrow22.4
BronchialEpithelialCells21.9
CD105+_Endothelial18.55
CD14+_Monocytes12.6
CD19+_BCells(neg._sel.)15.65
CD33+_Myeloid22.75
CD34+23
CD4+_Tcells22.4
CD56+_NKCells18.55
CD71+_EarlyErythroid17.9
CD8+_Tcells18.45
CardiacMyocytes26.35
Caudatenucleus17.5
Cerebellum17.1
CerebellumPeduncles23.35
CiliaryGanglion19.95
CingulateCortex20.4
Colorectaladenocarcinoma21.25
DorsalRootGanglion21.15
FetalThyroid18.6
Fetalbrain25.6
Fetalliver18.6
Fetallung17.4
GlobusPallidus14.5
Heart28.6
Hypothalamus20.05
Kidney15.75
Leukemia_chronicMyelogenousK-56217.05
Leukemia_promyelocytic-HL-6016.6
Leukemialymphoblastic(MOLT-4)12.4
Liver21.75
Lung21.25
Lymphnode25
Lymphoma_burkitts(Daudi)23.75
Lymphoma_burkitts(Raji)23.85
MedullaOblongata17.95
OccipitalLobe16.95
OlfactoryBulb15.4
Ovary13.45
Pancreas15.3
PancreaticIslet21.7
ParietalLobe20.15
Pituitary28.6
Placenta16.85
Pons21.35
PrefrontalCortex23.15
Prostate26.7
Salivarygland17.8
SkeletalMuscle22.4
Skin16.9
SmoothMuscle22.75
Spinalcord23.25
SubthalamicNucleus17.3
SuperiorCervicalGanglion23.7
TemporalLobe17.65
Testis30.75
TestisGermCell18.55
TestisIntersitial17.8
TestisLeydigCell19.25
TestisSeminiferousTubule19.25
Thalamus20.2
Thymus15.3
Thyroid27.7
Tongue19.65
Tonsil21.45
Trachea18.35
TrigeminalGanglion21.1
Uterus16.15
UterusCorpus19.75
WholeBlood15.45
Wholebrain16.15
colon22.4
pineal_day26.06
pineal_night27.12
retina22.925
small_intestine28.2
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_2301_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.9 ± 0.88
Basal Forebrain3.92 ± 0.5
Basal Part of Pons3.46 ± 0.6
Cerebellar Cortex4.04 ± 0.26
Cerebellar Nuclei3.69 ± 0.53
Claustrum3.77 ± 0.6
Epithalamus3.83 ± 0.74
Frontal Lobe3.39 ± 0.63
Globus Pallidus3.09 ± 0.55
Hypothalamus3.58 ± 0.67
Insula3.45 ± 0.48
Limbic Lobe3.37 ± 0.64
Mesencephalon3.51 ± 0.55
Myelencephalon3.53 ± 0.61
Occipital Lobe3.59 ± 0.72
Parietal Lobe3.6 ± 0.62
Pontine Tegmentum3.47 ± 0.72
Striatum3.21 ± 0.74
Subthalamus3.54 ± 0.06
Temporal Lobe3.54 ± 0.66
Thalamus3.64 ± 0.59
White Matter4.39 ± 0.62
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
H2afy2CBCerebellum34.54
37.62
H2afy2CTXCerebral cortex73.32
57.21
H2afy2HIPHippocampal region31.53
32.19
H2afy2HPFHippocampal formation43.76
40.27
H2afy2HYHypothalamus63.27
51.83
H2afy2LSXLateral septal complex35.64
31.09
H2afy2MBMidbrain45.09
40.87
H2afy2MYMedulla55.98
61.24
H2afy2OLFOlfactory bulb96.15
87.53
H2afy2PPons58.39
63.38
H2afy2PALPallidum51.59
45.37
H2afy2RHPRetrohippocampal region68.83
55.06
H2afy2sAMYStriatum-like amygdalar nuclei60.56
45.32
H2afy2STRStriatum53.51
40.69
H2afy2STRdStriatum dorsal region45.92
34.22
H2afy2STRvStriatum ventral region79.22
58.54
H2afy2THThalamus59.52
50.02
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00069466 17 80 96 HILLAVANDEELNQLLK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved