AutismKB 2.0

Annotation Detail for IL17RB


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Basic Information Top
Gene Symbol:IL17RB ( CRL4,EVI27,IL17BR,IL17RH1,MGC5245 )
Gene Full Name: interleukin 17 receptor B
Band: 3p21.1
Quick LinksEntrez ID:55540; OMIM: 605458; Uniprot ID:I17RB_HUMAN; ENSEMBL ID: ENSG00000056736; HGNC ID: 18015
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst1 / 6231916
fetus20 / 56401235
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult26 / 193912113
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor3 / 3436687
chondrosarcoma0 / 828230 
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor5 / 26384518
glioma1 / 1068839
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor2 / 9635920
lung tumor0 / 1031270 
lymphoma1 / 7175513
non-neoplasia0 / 972500 
normal73 / 336030721
ovarian tumor1 / 7668213
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland2 / 3319760
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain27 / 110098924
cervix4 / 4817183
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue1 / 2157224
esophagus0 / 202090 
eye2 / 2110549
heart3 / 8962633
intestine5 / 23447221
kidney15 / 21177770
larynx0 / 241450 
liver4 / 20774319
lung4 / 33697411
lymph0 / 442700 
lymph node4 / 9161043
mammary gland4 / 15327126
mouth0 / 670520 
muscle1 / 1077159
nerve1 / 1576863
ovary2 / 10205119
pancreas4 / 21481218
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta2 / 2808257
prostate0 / 1893450 
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach0 / 966190 
testis1 / 3304423
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus1 / 2328784
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 219255_x_at
Cell line Expression level Expression bar
721_B_lymphoblasts31.75
Adipocyte5.35
AdrenalCortex6.05
Adrenalgland4.7
Amygdala8.8
Appendix5.7
AtrioventricularNode4.35
BDCA4+_DentriticCells5.3
Bonemarrow5.25
BronchialEpithelialCells5
CD105+_Endothelial4.9
CD14+_Monocytes4.9
CD19+_BCells(neg._sel.)5.5
CD33+_Myeloid6.1
CD34+6.45
CD4+_Tcells5.35
CD56+_NKCells5.6
CD71+_EarlyErythroid5.15
CD8+_Tcells4.75
CardiacMyocytes7.45
Caudatenucleus6.1
Cerebellum12.85
CerebellumPeduncles8.55
CiliaryGanglion4.05
CingulateCortex7.8
Colorectaladenocarcinoma5.7
DorsalRootGanglion4.6
FetalThyroid5.45
Fetalbrain5.35
Fetalliver5.9
Fetallung4.9
GlobusPallidus4.6
Heart7.35
Hypothalamus10.5
Kidney60.65
Leukemia_chronicMyelogenousK-5625.15
Leukemia_promyelocytic-HL-604.4
Leukemialymphoblastic(MOLT-4)4.2
Liver9.25
Lung6.05
Lymphnode4.6
Lymphoma_burkitts(Daudi)6.85
Lymphoma_burkitts(Raji)7.8
MedullaOblongata6.45
OccipitalLobe5.6
OlfactoryBulb5.65
Ovary3.75
Pancreas4.55
PancreaticIslet6.65
ParietalLobe6.05
Pituitary6.6
Placenta5.05
Pons6.85
PrefrontalCortex38.35
Prostate6.85
Salivarygland4.5
SkeletalMuscle6.55
Skin4.35
SmoothMuscle5.85
Spinalcord9.65
SubthalamicNucleus5.05
SuperiorCervicalGanglion8.8
TemporalLobe5.2
Testis4.8
TestisGermCell5.4
TestisIntersitial4.75
TestisLeydigCell5.55
TestisSeminiferousTubule6.65
Thalamus6.15
Thymus4.45
Thyroid7
Tongue5.6
Tonsil5.45
Trachea4.7
TrigeminalGanglion5.55
Uterus4.65
UterusCorpus4.7
WholeBlood5.8
Wholebrain7.8
colon7.45
pineal_day7.4
pineal_night6.54
retina20.925
small_intestine5.55
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_10957_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.6 ± 0.53
Basal Forebrain4.95 ± 0.4
Basal Part of Pons4.02 ± 0.5
Cerebellar Cortex4.71 ± 0.3
Cerebellar Nuclei4.22 ± 0.69
Claustrum4.15 ± 0.6
Epithalamus4.81 ± 0.62
Frontal Lobe4.22 ± 0.58
Globus Pallidus5.52 ± 0.67
Hypothalamus4.59 ± 0.23
Insula4.28 ± 0.71
Limbic Lobe4.32 ± 0.64
Mesencephalon4.41 ± 0.62
Myelencephalon4.36 ± 0.65
Occipital Lobe4.53 ± 0.59
Parietal Lobe4.22 ± 0.68
Pontine Tegmentum4.43 ± 0.58
Striatum4.38 ± 0.6
Subthalamus3.9 ± 0.25
Temporal Lobe4.2 ± 0.53
Thalamus4.63 ± 0.51
White Matter5.1 ± 0.43
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Il17rbCBCerebellum6.5
4.86
Il17rbCTXCerebral cortex1.29
0.84
Il17rbHIPHippocampal region2.51
1.5
Il17rbHPFHippocampal formation3.38
2.1
Il17rbHYHypothalamus2.32
1.53
Il17rbLSXLateral septal complex0.38
0.28
Il17rbMBMidbrain2.93
1.76
Il17rbMYMedulla4.5
3.36
Il17rbOLFOlfactory bulb7.88
4.22
Il17rbPPons5.16
3.79
Il17rbPALPallidum0.69
0.47
Il17rbRHPRetrohippocampal region4.45
2.67
Il17rbsAMYStriatum-like amygdalar nuclei2.11
1.53
Il17rbSTRStriatum0.54
0.38
Il17rbSTRdStriatum dorsal region0.19
0.19
Il17rbSTRvStriatum ventral region1.04
0.49
Il17rbTHThalamus2.53
1.41
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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