Annotation Detail for PLXNA3
Basic Information Top
| Gene Symbol: | PLXNA3 ( 6.3,HSSEXGENE,PLEXIN-A3,PLXN3,PLXN4,SEX,XAP-6 ) |
|---|---|
| Gene Full Name: | plexin A3 |
| Band: | Xq28 |
| Quick Links | Entrez ID:55558; OMIM: 300022; Uniprot ID:PLXA3_HUMAN; ENSEMBL ID: ENSG00000130827; HGNC ID: 9101 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.632839
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 9 / 70761 | 127 |  |
| blastocyst | 1 / 62319 | 16 |  |
| fetus | 8 / 564012 | 14 | |
| neonate | 0 / 31097 | 0 | |
| infant | 0 / 23620 | 0 | |
| juvenile | 4 / 55556 | 71 | |
| adult | 69 / 1939121 | 35 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 2 / 17475 | 114 | |
| breast (mammary gland) tumor | 8 / 94178 | 84 | |
| cervical tumor | 0 / 34366 | 0 | |
| chondrosarcoma | 3 / 82823 | 36 | |
| colorectal tumor | 11 / 114246 | 96 | |
| esophageal tumor | 0 / 17290 | 0 | |
| gastrointestinal tumor | 1 / 119369 | 8 |  |
| germ cell tumor | 3 / 263845 | 11 | |
| glioma | 9 / 106883 | 84 | |
| head and neck tumor | 2 / 136302 | 14 | |
| kidney tumor | 4 / 68959 | 58 | |
| leukemia | 1 / 95842 | 10 | |
| liver tumor | 0 / 96359 | 0 | |
| lung tumor | 10 / 103127 | 96 | |
| lymphoma | 0 / 71755 | 0 | |
| non-neoplasia | 1 / 97250 | 10 | |
| normal | 67 / 3360307 | 19 | |
| ovarian tumor | 3 / 76682 | 39 | |
| pancreatic tumor | 3 / 104616 | 28 | |
| primitive neuroectodermal tumor of the CNS | 1 / 125680 | 7 | |
| prostate cancer | 1 / 102680 | 9 | |
| retinoblastoma | 0 / 46356 | 0 | |
| skin tumor | 2 / 124949 | 16 | |
| soft tissue/muscle tissue tumor | 1 / 125191 | 7 | |
| uterine tumor | 6 / 90257 | 66 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 0 / 13106 | 0 | |
| adrenal gland | 1 / 33197 | 30 | |
| ascites | 0 / 40015 | 0 | |
| bladder | 0 / 29757 | 0 | |
| blood | 3 / 123478 | 24 | |
| bone | 4 / 71655 | 55 | |
| bone marrow | 1 / 48801 | 20 | |
| brain | 20 / 1100989 | 18 | |
| cervix | 0 / 48171 | 0 | |
| connective tissue | 2 / 149255 | 13 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 11 / 215722 | 50 | |
| esophagus | 0 / 20209 | 0 | |
| eye | 2 / 211054 | 9 | |
| heart | 2 / 89626 | 22 | |
| intestine | 17 / 234472 | 72 | |
| kidney | 5 / 211777 | 23 | |
| larynx | 2 / 24145 | 82 | |
| liver | 0 / 207743 | 0 | |
| lung | 18 / 336974 | 53 | |
| lymph | 0 / 44270 | 0 | |
| lymph node | 2 / 91610 | 21 | |
| mammary gland | 9 / 153271 | 58 | |
| mouth | 0 / 67052 | 0 | |
| muscle | 0 / 107715 | 0 | |
| nerve | 4 / 15768 | 253 |  |
| ovary | 5 / 102051 | 48 | |
| pancreas | 3 / 214812 | 13 | |
| parathyroid | 0 / 20539 | 0 | |
| pharynx | 0 / 41328 | 0 | |
| pituitary gland | 0 / 16585 | 0 | |
| placenta | 1 / 280825 | 3 | |
| prostate | 3 / 189345 | 15 | |
| salivary gland | 0 / 20155 | 0 | |
| skin | 3 / 210574 | 14 | |
| spleen | 2 / 53952 | 37 | |
| stomach | 0 / 96619 | 0 | |
| testis | 4 / 330442 | 12 | |
| thymus | 1 / 81131 | 12 | |
| thyroid | 1 / 47473 | 21 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 0 / 52413 | 0 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 7 / 232878 | 30 | |
| vascular | 2 / 51780 | 38 | |
- Microarray Platform: GeneAtlas U133A, gcrma
- Affymatrix Probe ID: 203623_at
| Cell line | Expression level | Expression bar |
|---|---|---|
| ||
| 721_B_lymphoblasts | 6.25 | |
| Adipocyte | 5.3 | |
| AdrenalCortex | 5.6 | |
| Adrenalgland | 4.5 | |
| Amygdala | 5.8 | |
| Appendix | 5.55 | |
| AtrioventricularNode | 4.6 | |
| BDCA4+_DentriticCells | 5.7 | |
| Bonemarrow | 5.2 | |
| BronchialEpithelialCells | 5.3 | |
| CD105+_Endothelial | 5.45 | |
| CD14+_Monocytes | 5.6 | |
| CD19+_BCells(neg._sel.) | 5.8 | |
| CD33+_Myeloid | 6.45 | |
| CD34+ | 6.9 | |
| CD4+_Tcells | 6.3 | |
| CD56+_NKCells | 6.1 | |
| CD71+_EarlyErythroid | 4.95 | |
| CD8+_Tcells | 5.35 | |
| CardiacMyocytes | 7.4 | |
| Caudatenucleus | 4.8 | |
| Cerebellum | 4.4 | |
| CerebellumPeduncles | 6.2 | |
| CiliaryGanglion | 3.75 | |
| CingulateCortex | 5.45 | |
| Colorectaladenocarcinoma | 5.5 | |
| DorsalRootGanglion | 4.4 | |
| FetalThyroid | 5.2 | |
| Fetalbrain | 16.05 | |
| Fetalliver | 4.7 | |
| Fetallung | 4.5 | |
| GlobusPallidus | 3.9 | |
| Heart | 6.65 | |
| Hypothalamus | 5.85 | |
| Kidney | 4.25 | |
| Leukemia_chronicMyelogenousK-562 | 4.9 | |
| Leukemia_promyelocytic-HL-60 | 4.7 | |
| Leukemialymphoblastic(MOLT-4) | 4.35 | |
| Liver | 7.15 | |
| Lung | 6 | |
| Lymphnode | 4.65 | |
| Lymphoma_burkitts(Daudi) | 6.85 | |
| Lymphoma_burkitts(Raji) | 7.75 | |
| MedullaOblongata | 4.95 | |
| OccipitalLobe | 4.8 | |
| OlfactoryBulb | 11.5 | |
| Ovary | 3.6 | |
| Pancreas | 4.35 | |
| PancreaticIslet | 5.8 | |
| ParietalLobe | 5.8 | |
| Pituitary | 6.65 | |
| Placenta | 5.65 | |
| Pons | 5.1 | |
| PrefrontalCortex | 6.75 | |
| Prostate | 7.1 | |
| Salivarygland | 4.35 | |
| SkeletalMuscle | 6.2 | |
| Skin | 4.15 | |
| SmoothMuscle | 6.15 | |
| Spinalcord | 5.8 | |
| SubthalamicNucleus | 4.95 | |
| SuperiorCervicalGanglion | 6.35 | |
| TemporalLobe | 4.9 | |
| Testis | 4.7 | |
| TestisGermCell | 4.5 | |
| TestisIntersitial | 4.5 | |
| TestisLeydigCell | 5.35 | |
| TestisSeminiferousTubule | 4.6 | |
| Thalamus | 5.45 | |
| Thymus | 4.2 | |
| Thyroid | 6.85 | |
| Tongue | 5.4 | |
| Tonsil | 5.55 | |
| Trachea | 4.55 | |
| TrigeminalGanglion | 5.8 | |
| Uterus | 4.25 | |
| UterusCorpus | 4.95 | |
| WholeBlood | 5.85 | |
| Wholebrain | 4.55 | |
| colon | 5.35 | |
| pineal_day | 8.86 | |
| pineal_night | 6.64 | |
| retina | 6.525 | |
| small_intestine | 5.15 | |
- Probe name: CUST_8616_PI416261804
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 5.25 ± 0.62 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 6.07 ± 0.59 | |
| Basal Part of Pons | 3.94 ± 0.74 | |
| Cerebellar Cortex | 5.03 ± 0.53 | |
| Cerebellar Nuclei | 4.12 ± 0.68 | |
| Claustrum | 6.29 ± 1.03 | |
| Epithalamus | 4.79 ± 0.66 | |
| Frontal Lobe | 4.59 ± 0.88 | |
| Globus Pallidus | 5.69 ± 0.58 | |
| Hypothalamus | 5.79 ± 0.42 | |
| Insula | 4.64 ± 0.63 | |
| Limbic Lobe | 5.34 ± 0.99 | |
| Mesencephalon | 5.42 ± 0.88 | |
| Myelencephalon | 5.14 ± 0.85 | |
| Occipital Lobe | 5.27 ± 0.9 | |
| Parietal Lobe | 4.91 ± 1.03 | |
| Pontine Tegmentum | 4.89 ± 0.72 | |
| Striatum | 5.67 ± 0.88 | |
| Subthalamus | 4.63 ± 0.9 | |
| Temporal Lobe | 4.66 ± 0.83 | |
| Thalamus | 4.76 ± 0.74 | |
| White Matter | 6.48 ± 0.88 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Plxna3 | CB | Cerebellum | 0.66 | |
| 1.32 | | |||
| Plxna3 | CTX | Cerebral cortex | 0.36 | |
| 0.42 | | |||
| Plxna3 | HIP | Hippocampal region | 0.83 | |
| 0.48 | | |||
| Plxna3 | HPF | Hippocampal formation | 0.72 | |
| 0.55 | | |||
| Plxna3 | HY | Hypothalamus | 0.52 | |
| 0.28 | | |||
| Plxna3 | LSX | Lateral septal complex | 0.22 | |
| 0.17 | | |||
| Plxna3 | MB | Midbrain | 0.31 | |
| 0.25 | | |||
| Plxna3 | MY | Medulla | 0.99 | |
| 0.78 | | |||
| Plxna3 | OLF | Olfactory bulb | 4.52 | |
| 3.57 | | |||
| Plxna3 | P | Pons | 0.61 | |
| 0.71 | | |||
| Plxna3 | PAL | Pallidum | 0.11 | |
| 0.08 | | |||
| Plxna3 | RHP | Retrohippocampal region | 0.55 | |
| 0.51 | | |||
| Plxna3 | sAMY | Striatum-like amygdalar nuclei | 0.22 | |
| 0.17 | | |||
| Plxna3 | STR | Striatum | 0.14 | |
| 0.13 | | |||
| Plxna3 | STRd | Striatum dorsal region | 0.1 | |
| 0.13 | | |||
| Plxna3 | STRv | Striatum ventral region | 0.22 | |
| 0.13 | | |||
| Plxna3 | TH | Thalamus | 0.2 | |
| 0.15 | |
| Peptide Name | Peptide Lengh | Peptide Start | Peptide End | Peptide Sequence | Source |
|---|---|---|---|---|---|
| PLXA3_HUMAN_1322 | 10 | 1322 | 1331 | TPPNVEKALR | PRIDE |